메뉴 건너뛰기




Volumn 7, Issue 1, 1997, Pages 48-54

The genetics of visual system development in Drosophila: Specification, connectivity and asymmetry

Author keywords

[No Author keywords available]

Indexed keywords

CELL SPECIFICITY; COMPOUND EYE; DROSOPHILA; EYE DEVELOPMENT; GENE CONTROL; NERVE CELL DIFFERENTIATION; NERVE CELL NETWORK; NERVE FIBER; NONHUMAN; PHOTORECEPTOR; PRIORITY JOURNAL; RETINA DEVELOPMENT; REVIEW; VISUAL INFORMATION; VISUAL SYSTEM;

EID: 0031058341     PISSN: 09594388     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-4388(97)80119-5     Document Type: Article
Times cited : (21)

References (55)
  • 1
    • 0000258255 scopus 로고
    • Pattern formation in the Drosophila retina
    • M. Bate, Martinez-Arias A. Cold Spring Harbor: Cold Spring Harbor Laboratory Press
    • Wolff T, Ready DF. Pattern formation in the Drosophila retina. Bate M, Martinez-Arias A. The Development of Drosophila melanogaster. 1993;1277-1325 Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
    • (1993) The Development of Drosophila Melanogaster , pp. 1277-1325
    • Wolff, T.1    Ready, D.F.2
  • 2
    • 0000350127 scopus 로고
    • The development of the optic lobe
    • M. Bate, Martinez-Arias A. Cold Spring Harbor: Cold Spring Harbor Laboratory Press
    • Meinertzhagen IA, Hanson TE. The development of the optic lobe. Bate M, Martinez-Arias A. The Development of Drosophila melanogaster. 1993;1363-1492 Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
    • (1993) The Development of Drosophila Melanogaster , pp. 1363-1492
    • Meinertzhagen, I.A.1    Hanson, T.E.2
  • 4
    • 0029094930 scopus 로고
    • Early decisions in Drosophila eye morphogenesis
    • Bonini NM, Choi KW. Early decisions in Drosophila eye morphogenesis. Curr Opin Genet Dev. 5:1995;507-515.
    • (1995) Curr Opin Genet Dev , vol.5 , pp. 507-515
    • Bonini, N.M.1    Choi, K.W.2
  • 5
    • 0027965633 scopus 로고
    • Homology of the eyeless gene of Drosophila to the Small eye gene in mice and Aniridia in humans
    • Quiring R, Walldorf U, Kloter U, Gehring WJ. Homology of the eyeless gene of Drosophila to the Small eye gene in mice and Aniridia in humans. Science. 265:1994;785-789.
    • (1994) Science , vol.265 , pp. 785-789
    • Quiring, R.1    Walldorf, U.2    Kloter, U.3    Gehring, W.J.4
  • 6
    • 0028244770 scopus 로고
    • The Drosophila sine oculis locus encodes a homeodomain-containing protein required for development of the entire visual system
    • Cheyette BNR, Green PJ, Martin K, Garren H, Hartenstein V, Zipursky SL. The Drosophila sine oculis locus encodes a homeodomain-containing protein required for development of the entire visual system. Neuron. 12:1994;977-996.
    • (1994) Neuron , vol.12 , pp. 977-996
    • Cheyette, B.N.R.1    Green, P.J.2    Martin, K.3    Garren, H.4    Hartenstein, V.5    Zipursky, S.L.6
  • 7
    • 0028019609 scopus 로고
    • Sine oculis is a homeobox gene required for Drosophila visual system development
    • Serikaku MA, O'Tousa JE. sine oculis is a homeobox gene required for Drosophila visual system development. Genetics. 138:1994;1137-1150.
    • (1994) Genetics , vol.138 , pp. 1137-1150
    • Serikaku, M.A.1    O'Tousa, J.E.2
  • 8
    • 0028151047 scopus 로고
    • Dachshund encodes a nuclear protein required for normal eye and leg development in Drosophila
    • Mardon G, Solomon NM, Rubin GM. dachshund encodes a nuclear protein required for normal eye and leg development in Drosophila. Development. 120:1994;3473-3486.
    • (1994) Development , vol.120 , pp. 3473-3486
    • Mardon, G.1    Solomon, N.M.2    Rubin, G.M.3
  • 9
    • 0027510673 scopus 로고
    • The eyes absent gene: Genetic control of cell survival and differentiation in the developing Drosophila eye
    • Bonini NM, Leiserson WM, Benzer S. The eyes absent gene: genetic control of cell survival and differentiation in the developing Drosophila eye. Cell. 72:1993;379-395.
    • (1993) Cell , vol.72 , pp. 379-395
    • Bonini, N.M.1    Leiserson, W.M.2    Benzer, S.3
  • 10
    • 0028944665 scopus 로고
    • Induction of ectopic eyes by targeted expression of the eyeless gene in Drosophila
    • of outstanding interest. Ectopic expression of eyeless results in the formation of fully differentiated eyes on the legs, wings and antennae of Drosophila, demonstrating that eyeless, the Pax-6 homolog of flies, acts as a master control gene for eye morphogenesis.
    • Halder G, Callaerts P, Gehring WJ. Induction of ectopic eyes by targeted expression of the eyeless gene in Drosophila. of outstanding interest Science. 267:1995;1788-1792 Ectopic expression of eyeless results in the formation of fully differentiated eyes on the legs, wings and antennae of Drosophila, demonstrating that eyeless, the Pax-6 homolog of flies, acts as a master control gene for eye morphogenesis.
    • (1995) Science , vol.267 , pp. 1788-1792
    • Halder, G.1    Callaerts, P.2    Gehring, W.J.3
  • 11
    • 0031037843 scopus 로고    scopus 로고
    • Ectopic eye development in Drosophila induced by directed dachshund expression
    • of outstanding interest. Targeted expression of dachshund in Drosophila is sufficient to direct ectopic retinal development in head, thorax and legs, similar to the effects of ectopic eyeless expression [10]. The authors show further that dachshund and eyeless induced the expression of each other and that dachsund is required for eyeless-induced ectopic retinal development. These results suggest that the control of eye development requires, even at the highest regulatory level, the complex interaction of multiple genes.
    • Shen W, Mardon G. Ectopic eye development in Drosophila induced by directed dachshund expression. of outstanding interest Development. 124:1997;45-52 Targeted expression of dachshund in Drosophila is sufficient to direct ectopic retinal development in head, thorax and legs, similar to the effects of ectopic eyeless expression [10]. The authors show further that dachshund and eyeless induced the expression of each other and that dachsund is required for eyeless-induced ectopic retinal development. These results suggest that the control of eye development requires, even at the highest regulatory level, the complex interaction of multiple genes.
    • (1997) Development , vol.124 , pp. 45-52
    • Shen, W.1    Mardon, G.2
  • 14
    • 0029617682 scopus 로고
    • Six3, a murine homologue of the sine oculis gene, demarcates the most anterior border of the developing neural plate and is expressed during eye development
    • of special interest. Reports the isolation of Six3, a member of the Sixlso subclass of homeobox genes. Six3 is expressed in the anterior border of the developing neural plate and later on in eye development.
    • Oliver G, Mailhos A, Wehr R, Copeland NG, Jenkins NA, Gruss P. Six3, a murine homologue of the sine oculis gene, demarcates the most anterior border of the developing neural plate and is expressed during eye development. of special interest Development. 121:1995;4045-4055 Reports the isolation of Six3, a member of the Sixlso subclass of homeobox genes. Six3 is expressed in the anterior border of the developing neural plate and later on in eye development.
    • (1995) Development , vol.121 , pp. 4045-4055
    • Oliver, G.1    Mailhos, A.2    Wehr, R.3    Copeland, N.G.4    Jenkins, N.A.5    Gruss, P.6
  • 15
    • 0027993999 scopus 로고
    • On the evolution of eyes: Would you like it simple or compound?
    • Zuker CS. On the evolution of eyes: would you like it simple or compound? Science. 265:1994;742-743.
    • (1994) Science , vol.265 , pp. 742-743
    • Zuker, C.S.1
  • 16
    • 0029131888 scopus 로고
    • New perspectives on eye evolution
    • of special interest. In this review, the authors discuss the evolutionary implications of the finding that the vertebrate gene Pax-6 and the fly gene eyeless are molecularly and functionally conserved.
    • Halder G, Callaerts P, Gehring WJ. New perspectives on eye evolution. of special interest Curr Opin Genet Dev. 5:1995;602-609 In this review, the authors discuss the evolutionary implications of the finding that the vertebrate gene Pax-6 and the fly gene eyeless are molecularly and functionally conserved.
    • (1995) Curr Opin Genet Dev , vol.5 , pp. 602-609
    • Halder, G.1    Callaerts, P.2    Gehring, W.J.3
  • 17
    • 0027323503 scopus 로고
    • The embryonic development of the Drosophila visual system
    • Green P, Hartenstein AY, Hartenstein V. The embryonic development of the Drosophila visual system. Cell Tissue Res. 273:1993;583-598.
    • (1993) Cell Tissue Res , vol.273 , pp. 583-598
    • Green, P.1    Hartenstein, A.Y.2    Hartenstein, V.3
  • 18
    • 0028131581 scopus 로고
    • Pattern formation in the visual centers of the Drosophila brain: Wingless acts via decapentaplegic to specify the dorsovental axis
    • Kaphingst K, Kunes S. Pattern formation in the visual centers of the Drosophila brain: wingless acts via decapentaplegic to specify the dorsovental axis. Cell. 78:1994;437-448.
    • (1994) Cell , vol.78 , pp. 437-448
    • Kaphingst, K.1    Kunes, S.2
  • 19
    • 0028839101 scopus 로고
    • Mininbrain: A new protein kinase family involved in postembryonic neurogenesis in Drosophila
    • of special interest. The recently identified minibrain (mnb) gene encodes a serine/threonine kinase that shares sequence similarities with cyclin-dependent protein kinases. In mnb mutants, the size of the optic lobe is greatly reduced, which the authors attribute to the abnormal spacing of neuroblasts in the outer proliferation center.
    • Tejedor F, Zhu XR, Kaltenbach E, Ackermann A, Baumann A, Canal I, Heisenberg M, Fischbach KF, Pongs O. mininbrain: a new protein kinase family involved in postembryonic neurogenesis in Drosophila. of special interest Neuron. 14:1995;287-301 The recently identified minibrain (mnb) gene encodes a serine/threonine kinase that shares sequence similarities with cyclin-dependent protein kinases. In mnb mutants, the size of the optic lobe is greatly reduced, which the authors attribute to the abnormal spacing of neuroblasts in the outer proliferation center.
    • (1995) Neuron , vol.14 , pp. 287-301
    • Tejedor, F.1    Zhu, X.R.2    Kaltenbach, E.3    Ackermann, A.4    Baumann, A.5    Canal, I.6    Heisenberg, M.7    Fischbach, K.F.8    Pongs, O.9
  • 20
    • 0028880557 scopus 로고
    • The division abnormally delayed (dally) gene: A putative integral membrane proteoglycan required for cell division patterning during postembryonic development of the nervous system in Drosophila
    • of special interest. The dally gene, which encodes a putative integral membrane proteoglycan, is required for both divisions of the lamina precursor cells (LPCs) in the lamina anlage. In dally mutants, the first division is delayed, whereas the second, photoreceptor-triggered division does not take place at all. Interestingly, LPCs are still able to terminally differentiate as neurons.
    • Nakato H, Futch TA, Selleck SB. The division abnormally delayed (dally) gene: a putative integral membrane proteoglycan required for cell division patterning during postembryonic development of the nervous system in Drosophila. of special interest Development. 121:1995;3687-3702 The dally gene, which encodes a putative integral membrane proteoglycan, is required for both divisions of the lamina precursor cells (LPCs) in the lamina anlage. In dally mutants, the first division is delayed, whereas the second, photoreceptor-triggered division does not take place at all. Interestingly, LPCs are still able to terminally differentiate as neurons.
    • (1995) Development , vol.121 , pp. 3687-3702
    • Nakato, H.1    Futch, T.A.2    Selleck, S.B.3
  • 21
    • 0027788042 scopus 로고
    • The TGFβ homolog dpp and the segment polarity gene hedgehog are required for propagation of a morphogenetic wave in the Drosophila retina
    • Heberlein U, Wolff T, Rubin GM. The TGFβ homolog dpp and the segment polarity gene hedgehog are required for propagation of a morphogenetic wave in the Drosophila retina. Cell. 75:1993;913-926.
    • (1993) Cell , vol.75 , pp. 913-926
    • Heberlein, U.1    Wolff, T.2    Rubin, G.M.3
  • 22
    • 0027741258 scopus 로고
    • The segment polarity gene hedgehog is required for progression of the morphogenetic furrow in the developing Drosophila eye
    • Ma C, Zhou Y, Beachy PA, Moses K. The segment polarity gene hedgehog is required for progression of the morphogenetic furrow in the developing Drosophila eye. Cell. 75:1993;927-938.
    • (1993) Cell , vol.75 , pp. 927-938
    • Ma, C.1    Zhou, Y.2    Beachy, P.A.3    Moses, K.4
  • 23
    • 0026085328 scopus 로고
    • The influence of retinal innervation on neurogenesis in the first optic ganglion of Drosophila
    • Selleck SB, Steller H. The influence of retinal innervation on neurogenesis in the first optic ganglion of Drosophila. Neuron. 6:1991;83-99.
    • (1991) Neuron , vol.6 , pp. 83-99
    • Selleck, S.B.1    Steller, H.2
  • 24
    • 0026599349 scopus 로고
    • Regulation of the G1 - S transition in postembryonic neuronal precursors by axon ingrowth
    • Selleck SB, Gonzalez C, Glover DM, White K. Regulation of the G1 - S transition in postembryonic neuronal precursors by axon ingrowth. Nature. 355:1992;253-255.
    • (1992) Nature , vol.355 , pp. 253-255
    • Selleck, S.B.1    Gonzalez, C.2    Glover, D.M.3    White, K.4
  • 25
    • 0030576531 scopus 로고    scopus 로고
    • Hedgehog, transmitted along retinal axons, triggers neurogenesis in the developing visual centers of the Drosophila brain
    • of outstanding interest. Hedgehog, which is expressed in differentiating photoreceptors in the eye and is required for the induction of differentiation in precursor cells lying anteriorly, is transmitted along retinal axons and serves as an inductive signal in the brain. Hedgehog is required for the completion of the terminal cell cycle of lamina precursor cells, as well as for some aspects of their terminal differentiation.
    • Huang Z, Kunes S. Hedgehog, transmitted along retinal axons, triggers neurogenesis in the developing visual centers of the Drosophila brain. of outstanding interest Cell. 86:1996;411-422 Hedgehog, which is expressed in differentiating photoreceptors in the eye and is required for the induction of differentiation in precursor cells lying anteriorly, is transmitted along retinal axons and serves as an inductive signal in the brain. Hedgehog is required for the completion of the terminal cell cycle of lamina precursor cells, as well as for some aspects of their terminal differentiation.
    • (1996) Cell , vol.86 , pp. 411-422
    • Huang, Z.1    Kunes, S.2
  • 26
    • 0028872403 scopus 로고
    • Evidence that pioneer olfactory axons regulate telencephalon cell cycle kinetics to induce the formation of the olfactory bulb
    • Gong Q, Shipley MT. Evidence that pioneer olfactory axons regulate telencephalon cell cycle kinetics to induce the formation of the olfactory bulb. Neuron. 14:1995;91-101.
    • (1995) Neuron , vol.14 , pp. 91-101
    • Gong, Q.1    Shipley, M.T.2
  • 27
    • 0026453672 scopus 로고
    • Generation and early differentiation of glial cells in the first optic ganglion of Drosophila melanogaster
    • Winberg ML, Perez SE, Steller H. Generation and early differentiation of glial cells in the first optic ganglion of Drosophila melanogaster. Development. 115:1992;903-911.
    • (1992) Development , vol.115 , pp. 903-911
    • Winberg, M.L.1    Perez, S.E.2    Steller, H.3
  • 28
    • 0028346801 scopus 로고
    • Migration of glia along photoreceptor axons in the developing Drosophila eye
    • Choi K-W, Benzer S. Migration of glia along photoreceptor axons in the developing Drosophila eye. Neuron. 12:1994;423-431.
    • (1994) Neuron , vol.12 , pp. 423-431
    • Choi, K.-W.1    Benzer, S.2
  • 29
    • 0028916322 scopus 로고
    • Defective glia induce neuronal apoptosis in the repo visual system of Drosophila
    • of special interest. The reversed polarity (repo) gene is a pan-glial marker for the visual system. Mutations in repo cause abnormal terminal diffrentiation of the glia and lead to concomitant apoptosis of lamina neurons and glia, followed by retrograde degeneration of photoreceptors in the retina.
    • Xiong WC, Montell C. Defective glia induce neuronal apoptosis in the repo visual system of Drosophila. of special interest Neuron. 14:1995;581-590 The reversed polarity (repo) gene is a pan-glial marker for the visual system. Mutations in repo cause abnormal terminal diffrentiation of the glia and lead to concomitant apoptosis of lamina neurons and glia, followed by retrograde degeneration of photoreceptors in the retina.
    • (1995) Neuron , vol.14 , pp. 581-590
    • Xiong, W.C.1    Montell, C.2
  • 30
    • 0027510615 scopus 로고
    • Independent guidance of retinal axons in the developing visual system of Drosophila
    • Kunes S, Wilson C, Steller H. Independent guidance of retinal axons in the developing visual system of Drosophila. J Neurosci. 13:1993;752-767.
    • (1993) J Neurosci , vol.13 , pp. 752-767
    • Kunes, S.1    Wilson, C.2    Steller, H.3
  • 31
    • 0028229496 scopus 로고
    • Competition and position-dependent targeting in the development of the Drosophila R7 visual projections
    • Ashley JA, Katz FN. Competition and position-dependent targeting in the development of the Drosophila R7 visual projections. Development. 120:1994;1537-1547.
    • (1994) Development , vol.120 , pp. 1537-1547
    • Ashley, J.A.1    Katz, F.N.2
  • 33
    • 0029164630 scopus 로고
    • Eph receptor tyrosine kinases, axon repulsion, and the development of topographic maps
    • Tessier-Lavigne M. Eph receptor tyrosine kinases, axon repulsion, and the development of topographic maps. Cell. 82:1995;345-348.
    • (1995) Cell , vol.82 , pp. 345-348
    • Tessier-Lavigne, M.1
  • 34
    • 0029082312 scopus 로고
    • In vitro guidance of retinal ganglion cell axons by RAGS, a 25 kDa tectal protein related to ligands for Eph receptor tyrosine kinases
    • Drescher U, Kremoser C, Handwerker C, Löschinger J, Noda M, Bonhoeffer F. In vitro guidance of retinal ganglion cell axons by RAGS, a 25 kDa tectal protein related to ligands for Eph receptor tyrosine kinases. Cell. 82:1995;359-370.
    • (1995) Cell , vol.82 , pp. 359-370
    • Drescher, U.1    Kremoser, C.2    Handwerker, C.3    Löschinger, J.4    Noda, M.5    Bonhoeffer, F.6
  • 35
    • 0029086140 scopus 로고
    • Complementary gradients in expression and binding of ELF-1 and Mek4 in development of the topographic retinotectal projection map
    • Cheng HJ, Nakamoto M, Bergemann AD, Flanagan JG. Complementary gradients in expression and binding of ELF-1 and Mek4 in development of the topographic retinotectal projection map. Cell. 82:1995;371-381.
    • (1995) Cell , vol.82 , pp. 371-381
    • Cheng, H.J.1    Nakamoto, M.2    Bergemann, A.D.3    Flanagan, J.G.4
  • 36
    • 0028890451 scopus 로고
    • Mutations disrupting neuronal connectivity in the Drosophila visual system
    • of special interest. In an elegant histological screen, recessive mutations on the X and third chromosome that disrupt retinal connectivity were isolated. Genes were identified as candidates for playing direct roles in axonal outgrowth, target recognition and retinotopy.
    • Martin KA, Poeck B, Roth H, Ebens AJ, Ballard LC, Zipursky SL. Mutations disrupting neuronal connectivity in the Drosophila visual system. of special interest Neuron. 14:1995;229-240 In an elegant histological screen, recessive mutations on the X and third chromosome that disrupt retinal connectivity were isolated. Genes were identified as candidates for playing direct roles in axonal outgrowth, target recognition and retinotopy.
    • (1995) Neuron , vol.14 , pp. 229-240
    • Martin, K.A.1    Poeck, B.2    Roth, H.3    Ebens, A.J.4    Ballard, L.C.5    Zipursky, S.L.6
  • 37
    • 0029943447 scopus 로고    scopus 로고
    • Drosophila photoreceptor axon guidance and targeting requires the dreadlocks SH2/SH3 adapter protein
    • of outstanding interest. Molecular analysis of the dreadlocks (dock) gene, which was identified on the basis of its mutant phenotype and is characterized by defects in retinal axon guidance and targeting. The Dock protein is highly related to the human proto-oncogene Nck and is highly enriched in photoreceptor growth cones in the target region, suggesting that it is involved in signal transduction in the growth cone.
    • Garrity PA, Rao Y, Salecker I, McGlade J, Pawson T, Zipursky SL. Drosophila photoreceptor axon guidance and targeting requires the dreadlocks SH2/SH3 adapter protein. of outstanding interest Cell. 85:1996;639-650 Molecular analysis of the dreadlocks (dock) gene, which was identified on the basis of its mutant phenotype and is characterized by defects in retinal axon guidance and targeting. The Dock protein is highly related to the human proto-oncogene Nck and is highly enriched in photoreceptor growth cones in the target region, suggesting that it is involved in signal transduction in the growth cone.
    • (1996) Cell , vol.85 , pp. 639-650
    • Garrity, P.A.1    Rao, Y.2    Salecker, I.3    McGlade, J.4    Pawson, T.5    Zipursky, S.L.6
  • 38
    • 0027767583 scopus 로고
    • The irregular chiasm C-roughest locus of Drosophila, which affects axonal projectios and programmed cell death, encodes a novel immunoglobulin-like protein
    • Ramos RGP, Igloi GL, Lichte B, Baumann U, Maier D, Schneider T, Bradstätter JH, Fröhlich A, Fischbach KF. The irregular chiasm C-roughest locus of Drosophila, which affects axonal projectios and programmed cell death, encodes a novel immunoglobulin-like protein. Genes Dev. 7:1993;2533-2547.
    • (1993) Genes Dev , vol.7 , pp. 2533-2547
    • Ramos, R.G.P.1    Igloi, G.L.2    Lichte, B.3    Baumann, U.4    Maier, D.5    Schneider, T.6    Bradstätter, J.H.7    Fröhlich, A.8    Fischbach, K.F.9
  • 39
    • 0029166015 scopus 로고
    • Restricted expression of the irreC-rst protein is required for normal axonal projections of columnar visual neurons
    • of special interest. The irreC - rst protein is an immunoglobulin superfamily member that mediates homophilic adhesion in vitro. The protein is expressed in a highly dynamic pattern in subsets of young axons throughout the visual system. Ubiquitous expressions of the protein results in phenotypes similar to complete loss of protein, suggesting that spatial restriction of expression is essential for the function of the molecule.
    • Schneider T, Reiter C, Eule E, Bader B, Lichte B, Nie Z, Schimansky T, Ramos RGP, Fischbach KF. Restricted expression of the irreC-rst protein is required for normal axonal projections of columnar visual neurons. of special interest Neuron. 15:1995;259-271 The irreC - rst protein is an immunoglobulin superfamily member that mediates homophilic adhesion in vitro. The protein is expressed in a highly dynamic pattern in subsets of young axons throughout the visual system. Ubiquitous expressions of the protein results in phenotypes similar to complete loss of protein, suggesting that spatial restriction of expression is essential for the function of the molecule.
    • (1995) Neuron , vol.15 , pp. 259-271
    • Schneider, T.1    Reiter, C.2    Eule, E.3    Bader, B.4    Lichte, B.5    Nie, Z.6    Schimansky, T.7    Ramos, R.G.P.8    Fischbach, K.F.9
  • 40
    • 0029818996 scopus 로고    scopus 로고
    • Genetic analysis of Laminin A in Drosophila: Extracellular matrix containing laminin A is required for ocellar axon pathfinding
    • of special interest. Partial loss-of-function mutations in laminin A are examined for axon pathfinding defects in the sensory neurons of the fly head. Ocellar pioneer axons fail to project to their target in the brain, while neighboring mechanosensory axons project normally, suggesting that differential expression of laminin receptors by different sensory growth cones may regulate pathway choice.
    • Garcia-Alonso L, Fetter RD, Goodman CS. Genetic analysis of Laminin A in Drosophila: extracellular matrix containing laminin A is required for ocellar axon pathfinding. of special interest Development. 122:1996;2611-2622 Partial loss-of-function mutations in laminin A are examined for axon pathfinding defects in the sensory neurons of the fly head. Ocellar pioneer axons fail to project to their target in the brain, while neighboring mechanosensory axons project normally, suggesting that differential expression of laminin receptors by different sensory growth cones may regulate pathway choice.
    • (1996) Development , vol.122 , pp. 2611-2622
    • Garcia-Alonso, L.1    Fetter, R.D.2    Goodman, C.S.3
  • 41
    • 0002471103 scopus 로고
    • Neuroarchitecture of brain regions that subserve the compound eye of crustacea and insects
    • Autrum H. New York: Springer-Verlag
    • Strausfeld NJ, Nässel DR. Neuroarchitecture of brain regions that subserve the compound eye of crustacea and insects. Autrum H. Handbook of Sensory Physiology. VII/6B:1981;1-132 Springer-Verlag, New York.
    • (1981) Handbook of Sensory Physiology , vol.76 , pp. 1-132
    • Strausfeld, N.J.1    Nässel, D.R.2
  • 42
    • 0022272271 scopus 로고
    • The cellular dynamics of pattern formation in the eye of Drosophila
    • Tomlinson A. The cellular dynamics of pattern formation in the eye of Drosophila. J Embryol Exp Morphol. 89:1985;313-331.
    • (1985) J Embryol Exp Morphol , vol.89 , pp. 313-331
    • Tomlinson, A.1
  • 43
    • 0025759978 scopus 로고
    • Stereociliary bundles reorient during hair cell development and regeneration in the chick cochlea
    • Cotanche DA, Corwin JT. Stereociliary bundles reorient during hair cell development and regeneration in the chick cochlea. Hearing Res. 52:1991;379-402.
    • (1991) Hearing Res , vol.52 , pp. 379-402
    • Cotanche, D.A.1    Corwin, J.T.2
  • 44
    • 0029558479 scopus 로고
    • Ommatidial polarity in the Drosophila eye is determined by the direction of furrow progression and local interactions
    • of special interest. See annotation [47].
    • Strutt DI, Mlodzik M. Ommatidial polarity in the Drosophila eye is determined by the direction of furrow progression and local interactions. of special interest Development. 121:1995;4247-4256 See annotation [47].
    • (1995) Development , vol.121 , pp. 4247-4256
    • Strutt, D.I.1    Mlodzik, M.2
  • 45
    • 0029027102 scopus 로고
    • Epithelial planar polarity in the developing Drosophila eye
    • of special interest. See annotation [47].
    • Wehrli M, Tomlinson A. Epithelial planar polarity in the developing Drosophila eye. of special interest Development. 121:1995;2451-2459 See annotation [47].
    • (1995) Development , vol.121 , pp. 2451-2459
    • Wehrli, M.1    Tomlinson, A.2
  • 46
    • 0029022144 scopus 로고
    • Wingless and patched are negative regulators of the morphogenetic furrow and can affect tissue polarity in the developing Drosophila compound eye
    • of special interest. See annotation [47].
    • Ma C, Moses K. wingless and patched are negative regulators of the morphogenetic furrow and can affect tissue polarity in the developing Drosophila compound eye. of special interest Development. 121:1995;2279-2289 See annotation [47].
    • (1995) Development , vol.121 , pp. 2279-2289
    • Ma, C.1    Moses, K.2
  • 47
    • 0029559250 scopus 로고
    • Role of the morphogenetic furrow in establishing polarity in the Drosophila eye
    • of special interest. These four papers [44-47] present similar results, examining the influence of ectopic morphogenectic furrows on ommatidial polarity in Drosophila. By removing patched, wingless or pKA-C1 function in mosaic clones or by misexpressing Hedgehog, a second furrow that directly determines the anteroposterior axis of the ommatidia in its wake is initiated. Chanut and Heberlein [47] show further that genetic markers of dorsal and equatorial identity are induced in imaginal discs with ectopic furrows. Although the authors' interpretations of their findings are not in complete agreement, it appears that the center-outward front of the furrow acts as a point source to organize dorsoventral polarity.
    • Chanut F, Heberlein U. Role of the morphogenetic furrow in establishing polarity in the Drosophila eye. of special interest Development. 121:1995;4085-4094 These four papers [44-47] present similar results, examining the influence of ectopic morphogenectic furrows on ommatidial polarity in Drosophila. By removing patched, wingless or pKA-C1 function in mosaic clones or by misexpressing Hedgehog, a second furrow that directly determines the anteroposterior axis of the ommatidia in its wake is initiated. Chanut and Heberlein [47] show further that genetic markers of dorsal and equatorial identity are induced in imaginal discs with ectopic furrows. Although the authors' interpretations of their findings are not in complete agreement, it appears that the center-outward front of the furrow acts as a point source to organize dorsoventral polarity.
    • (1995) Development , vol.121 , pp. 4085-4094
    • Chanut, F.1    Heberlein, U.2
  • 48
    • 0024972122 scopus 로고
    • A Drosophila tissue polarity locus encodes a protein containing seven potential transmembrane domains
    • Vinson CR, Conover S, Adler PN. A Drosophila tissue polarity locus encodes a protein containing seven potential transmembrane domains. Nature. 338:1989;263-264.
    • (1989) Nature , vol.338 , pp. 263-264
    • Vinson, C.R.1    Conover, S.2    Adler, P.N.3
  • 49
    • 0029145518 scopus 로고
    • Frizzled regulates mirror-symmetric pattern formation in the Drosophila eye
    • of outstanding interest. A detailed developmental analysis of frizzled function leads to the conclusion that this gene responds to a graded signal emanating from the dorsoventral equator during eye development. Genetic mosaics demonstrate that the relative levels of frizzled influence the fate of the R3 and R4 photoreceptors, which will influence the direction of ommatidial rotation. The expression of nemo and second gene that marks the equator are both abolished in frizzled mutants.
    • Zheng L, Zhang J, Carthew RW. frizzled regulates mirror-symmetric pattern formation in the Drosophila eye. of outstanding interest Development. 121:1995;3045-3055 A detailed developmental analysis of frizzled function leads to the conclusion that this gene responds to a graded signal emanating from the dorsoventral equator during eye development. Genetic mosaics demonstrate that the relative levels of frizzled influence the fate of the R3 and R4 photoreceptors, which will influence the direction of ommatidial rotation. The expression of nemo and second gene that marks the equator are both abolished in frizzled mutants.
    • (1995) Development , vol.121 , pp. 3045-3055
    • Zheng, L.1    Zhang, J.2    Carthew, R.W.3
  • 50
    • 0029994517 scopus 로고    scopus 로고
    • A new member of the frizzled family from Drosophila functions as a wingless receptor
    • of outstanding interest. Identification of a second frizzled homolog (Dfz2) in Drosophila, coupled with biochemical analysis, supports the notion that Frizzled family members may represent the long-south-after receptors for Wnt/Wg signaling proteins. Cells transfected with Dfz2 exhibit an expected intracellular response (namely an increased in levels of Armadillo) to Wg protein and are able to bind Wg. The domain of Dfz2 responsible for binding has been localized to the amino-terminal extracellular region. A subset of mammalian frizzled homologs tested in the transfection assay are also able to confer Wg binding.
    • Bhanot P, Brink M, Samos CH, Hsieh JC, Wang Y, Macke JP, Andrew D, Nathans J, Nusse R. A new member of the frizzled family from Drosophila functions as a wingless receptor. of outstanding interest Nature. 382:1996;225-230 Identification of a second frizzled homolog (Dfz2) in Drosophila, coupled with biochemical analysis, supports the notion that Frizzled family members may represent the long-south-after receptors for Wnt/Wg signaling proteins. Cells transfected with Dfz2 exhibit an expected intracellular response (namely an increased in levels of Armadillo) to Wg protein and are able to bind Wg. The domain of Dfz2 responsible for binding has been localized to the amino-terminal extracellular region. A subset of mammalian frizzled homologs tested in the transfection assay are also able to confer Wg binding.
    • (1996) Nature , vol.382 , pp. 225-230
    • Bhanot, P.1    Brink, M.2    Samos, C.H.3    Hsieh, J.C.4    Wang, Y.5    Macke, J.P.6    Andrew, D.7    Nathans, J.8    Nusse, R.9
  • 51
    • 0029417002 scopus 로고
    • Dishevelled is a component of the frizzled signaling pathway in Drosophila
    • Krasnow RE, Wong L, Adler PN. dishevelled is a component of the frizzled signaling pathway in Drosophila. Development. 121:1995;4095-4102.
    • (1995) Development , vol.121 , pp. 4095-4102
    • Krasnow, R.E.1    Wong, L.2    Adler, P.N.3
  • 52
    • 0028178391 scopus 로고
    • Dishevelled is required during wingless signaling to establish-both cell polarity and cell identity
    • Theisen H, Purcell J, Bennett M, Kansagara D, Syed A, Marsh JL. dishevelled is required during wingless signaling to establish-both cell polarity and cell identity. Development. 120:1994;347-360.
    • (1994) Development , vol.120 , pp. 347-360
    • Theisen, H.1    Purcell, J.2    Bennett, M.3    Kansagara, D.4    Syed, A.5    Marsh, J.L.6
  • 53
    • 0028364608 scopus 로고
    • Rotation of photoreceptor clusters in the developing Drosophila eye requires the nemo gene
    • Choi KW, Benzer S. Rotation of photoreceptor clusters in the developing Drosophila eye requires the nemo gene. Cell. 78:1994;125-136.
    • (1994) Cell , vol.78 , pp. 125-136
    • Choi, K.W.1    Benzer, S.2
  • 54
    • 0030598904 scopus 로고    scopus 로고
    • The role of the genome project in determining gene function: Insights from model organisms
    • Miklos GLG, Rubin GM. The role of the genome project in determining gene function: insights from model organisms. Cell. 86:1996;521-529.
    • (1996) Cell , vol.86 , pp. 521-529
    • Miklos, G.L.G.1    Rubin, G.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.