Paternal uniparental disomy for chromosome 6 causes transient neonatal diabetes

Journal of Medical Genetics

Volumn 34, Issue 2, 1997, Pages 167-168

  Whiteford, M L ^a   Narendra, A ^b   White, M P ^b   Cooke, A ^a   Wilkinson, A G ^c   Robertson, K J ^c   Tolmie, J L ^a  

^a NHS GREATER GLASGOW AND CLYDE   (United Kingdom)

^b SOUTHERN GENERAL HOSPITAL   (United Kingdom)

^c ROYAL HOSPITAL FOR SICK CHILDREN   (United Kingdom)

Author keywords

Chromosome 6; Paternal uniparental disomy; Transient neonatal diabetes

Indexed keywords

INSULIN;

ARTICLE; CASE REPORT; CHROMOSOME 6; DIABETES MELLITUS; HUMAN; INTRAUTERINE GROWTH RETARDATION; MALE; NEWBORN; PRIORITY JOURNAL; SUBCUTANEOUS DRUG ADMINISTRATION; UNIPARENTAL DISOMY;

EID: 0031057955     PISSN: 00222593     EISSN: None     Source Type: Journal    
DOI: 10.1136/jmg.34.2.167     Document Type: Article

References (9)

1. Temple IK, James RS, Crolla JA, et al. An imprinted gene(s) for diabetes? Nat Genet 1995;9:110-12.
2. Abramowicz MJ, Andrien M, Dupont E, et al. Isodisomy of chromosome 6 in a newborn with methylmalonic acidaemia and agenesis of the pancreatic beta cells causing diabetes mellitus. J Clin Invest 1994;94:418-21.
3. Gentz JCH, Cornblath M. Transient diabetes of the newborn. Adv Pediatr 1969;16:345-63.
4. Vanelli M, DeFanti A, Cantoni S, et al. Transient neonatal diabetes mellitus: a relapse after 10 years of complete remission. Acta Diabetol 1994;31:116-18.
5. Shield JPH, Baum JD. Is transient neonatal diabetes a risk factor for diabetes later in life? Lancet 1993;341:693.
6. Weimerskirch D, Klein DJ. Recurrence of insulin-dependent diabetes after transient neonatal diabetes: a report of two cases. J Pediatr 1993;122:558-60.
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8. Temple IK, Gardner RJ, Robinson DO, et al. Further evidence for an imprinted gene for neonatal diabetes localised to chromosome 6q22-q23. Hum Mol Genet 1996;5: 1117-21.
9. Pivnik EK, Qumsieyeh MB, Tharapel AT, et al. Partial duplication of the long arm of chromosome 6: a clinically recognisable syndrome. J Med Genet 1990;27:523-6.