-
2
-
-
0022539516
-
High yields of lethal mutations in somatic mammalian cells that survive ionizing radiation
-
C. B. Seymour, C. Mothersill and T. Alper, High yields of lethal mutations in somatic mammalian cells that survive ionizing radiation. Int. J. Radiat. Biol. 50, 167-179 (1986).
-
(1986)
Int. J. Radiat. Biol.
, vol.50
, pp. 167-179
-
-
Seymour, C.B.1
Mothersill, C.2
Alper, T.3
-
3
-
-
0026515714
-
Transmission of chromosomal instability after plutonium α-particle irradiation
-
M. A. Kadhim, D. A. Macdonald, D. T. Goodhead, S. A. Lorimore, S. J. Marsden and E. J. Wright, Transmission of chromosomal instability after plutonium α-particle irradiation. Nature 355, 738-740 (1992).
-
(1992)
Nature
, vol.355
, pp. 738-740
-
-
Kadhim, M.A.1
Macdonald, D.A.2
Goodhead, D.T.3
Lorimore, S.A.4
Marsden, S.J.5
Wright, E.J.6
-
4
-
-
0027402507
-
Recovery of the radiation survival-curve shoulder in CHO-K1, XRS-5 and revenant XRS-5 populations
-
C. Mothersill and C. B. Seymour. Recovery of the radiation survival-curve shoulder in CHO-K1, XRS-5 and revenant XRS-5 populations. Mutat. Res. 285, 259-266 (1993).
-
(1993)
Mutat. Res.
, vol.285
, pp. 259-266
-
-
Mothersill, C.1
Seymour, C.B.2
-
5
-
-
0027380346
-
Delayed chromosomal instability induced by DNA damage
-
B. A. Marder and W. F. Morgan, Delayed chromosomal instability induced by DNA damage. Mol. Cell. Biol. 13, 6667-6677 (1993).
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 6667-6677
-
-
Marder, B.A.1
Morgan, W.F.2
-
6
-
-
0026588513
-
All colonies of CHO-K1 cells surviving γ-radiation contain non-viable cells
-
C. B. Seymour and C. Mothersill, All colonies of CHO-K1 cells surviving γ-radiation contain non-viable cells. Mutat, Res. 267, 19-30 (1992).
-
(1992)
Mutat, Res.
, vol.267
, pp. 19-30
-
-
Seymour, C.B.1
Mothersill, C.2
-
7
-
-
0028920188
-
Radiation-induced genomic instability: Delayed cytogenetic aberrations and apoptosis in primary human bone marrow cells
-
M. A. Kadhim, S. A. Lorimore, K. M. S. Townsend, D. T. Goodhead, V. J. Buckle and E. J. Wright, Radiation-induced genomic instability: delayed cytogenetic aberrations and apoptosis in primary human bone marrow cells. Int. J. Radiat. Biol. 67, 287-293 (1995).
-
(1995)
Int. J. Radiat. Biol.
, vol.67
, pp. 287-293
-
-
Kadhim, M.A.1
Lorimore, S.A.2
Townsend, K.M.S.3
Goodhead, D.T.4
Buckle, V.J.5
Wright, E.J.6
-
8
-
-
0028929328
-
Mechanisms and genes of cellular suicide
-
H. Stellar, Mechanisms and genes of cellular suicide. Science 267. 1445-1449 (1995).
-
(1995)
Science
, vol.267
, pp. 1445-1449
-
-
Stellar, H.1
-
9
-
-
1842309354
-
Participation of the p53 protein in the response to DNA damage
-
M. B. Kasten, O. Onyekwere, D. Sidransky, B. Vogelstein and R. B. Craig. Participation of the p53 protein in the response to DNA damage. Cancer Res. 50, 7754-7759 (1991).
-
(1991)
Cancer Res.
, vol.50
, pp. 7754-7759
-
-
Kasten, M.B.1
Onyekwere, O.2
Sidransky, D.3
Vogelstein, B.4
Craig, R.B.5
-
10
-
-
0027235369
-
A death in the life of p53
-
[News]
-
D. P. Lane, A death in the life of p53. Nature 362, 786-787 (1993). [News]
-
(1993)
Nature
, vol.362
, pp. 786-787
-
-
Lane, D.P.1
-
11
-
-
0028059964
-
Mechanisms of apoptosis: Integration of genetic, biochemical and cellular indicators
-
B. W. Stewart, Mechanisms of apoptosis: integration of genetic, biochemical and cellular indicators. J. Natl. Cancer Inst. 86. 1286-1296 (1994).
-
(1994)
J. Natl. Cancer Inst.
, vol.86
, pp. 1286-1296
-
-
Stewart, B.W.1
-
12
-
-
0023779204
-
Alternative promoters and exons, somatic mutation and deregulation of the Bcl-2-Ig fusion gene in lymphoma
-
M. Seto, U. Jaeger, R. D. Hockett, W. Grainger, S. Bennett, P. Goldman and S. J. Korsmeyer, Alternative promoters and exons, somatic mutation and deregulation of the Bcl-2-Ig fusion gene in lymphoma. EMBO J. 7, 123-131 (1988).
-
(1988)
EMBO J.
, vol.7
, pp. 123-131
-
-
Seto, M.1
Jaeger, U.2
Hockett, R.D.3
Grainger, W.4
Bennett, S.5
Goldman, P.6
Korsmeyer, S.J.7
-
13
-
-
0026688162
-
Apoptotic death induced by Myc is inhibited by bcl-2
-
R. P. Bissonette, F. Echeverri, A. Mahboubi and D. R. Green, Apoptotic death induced by Myc is inhibited by bcl-2. Nature 359, 552-555 (1992).
-
(1992)
Nature
, vol.359
, pp. 552-555
-
-
Bissonette, R.P.1
Echeverri, F.2
Mahboubi, A.3
Green, D.R.4
-
14
-
-
0027282044
-
Bcl-x, a bcl-2 related gene that functions as a dominant regulator of apoptotic cell death
-
L. H. Boise, M. Gonzales-Garcia, C. E. Postema, L. Ding, T. Lindsten, L. A. Turka, X. Mao, G. Nunez and C. B. Thompson, Bcl-x, a bcl-2 related gene that functions as a dominant regulator of apoptotic cell death. Cell 74, 597-608 (1993).
-
(1993)
Cell
, vol.74
, pp. 597-608
-
-
Boise, L.H.1
Gonzales-Garcia, M.2
Postema, C.E.3
Ding, L.4
Lindsten, T.5
Turka, L.A.6
Mao, X.7
Nunez, G.8
Thompson, C.B.9
-
15
-
-
0028148353
-
Apoptosis and a re-investigation of the biologic basis for cancer therapy
-
A. V. D'Amico and W. G. McKenna, Apoptosis and a re-investigation of the biologic basis for cancer therapy. Radiother. Oncol. 33, 3-10 (1994).
-
(1994)
Radiother. Oncol.
, vol.33
, pp. 3-10
-
-
D'Amico, A.V.1
McKenna, W.G.2
-
16
-
-
0027513663
-
Myc-mediated apoptosis is blocked by ectopic expression of bcl-2
-
A. J. Wagner, M. B. Small and N. Hay, Myc-mediated apoptosis is blocked by ectopic expression of bcl-2. Mol. Cell. Biol. 13, 2432-2440 (1993).
-
(1993)
Mol. Cell. Biol.
, vol.13
, pp. 2432-2440
-
-
Wagner, A.J.1
Small, M.B.2
Hay, N.3
-
17
-
-
0026496885
-
A mammalian cell-cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia telangiectasia
-
M. B. Kasten, Q. Zhan, W. S. El-Deiry, F. Carrier, T. Jacks, B. S. Walsh, B. Plunkett, B. Vogelstein and A. J. Fornace, Jr., A mammalian cell-cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia telangiectasia. Cell 71, 587-597 (1992).
-
(1992)
Cell
, vol.71
, pp. 587-597
-
-
Kasten, M.B.1
Zhan, Q.2
El-Deiry, W.S.3
Carrier, F.4
Jacks, T.5
Walsh, B.S.6
Plunkett, B.7
Vogelstein, B.8
Fornace Jr., A.J.9
-
18
-
-
0027485461
-
Bcl-2 functions in an antioxidant pathway to prevent apoptosis
-
D. M. Hockenberry, Z. N. Oltvai, X. M. Yin, C. L. Milliman and S. J. Korsmeyer, Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 75, 241-251 (1993).
-
(1993)
Cell
, vol.75
, pp. 241-251
-
-
Hockenberry, D.M.1
Oltvai, Z.N.2
Yin, X.M.3
Milliman, C.L.4
Korsmeyer, S.J.5
-
19
-
-
0026655474
-
Bcl-2 initiates a new category of oncogenes: Regulators of cell death
-
S. J. Korsmeyer, Bcl-2 initiates a new category of oncogenes: regulators of cell death. Blood 80, 879-886 (1992).
-
(1992)
Blood
, vol.80
, pp. 879-886
-
-
Korsmeyer, S.J.1
-
20
-
-
0027166048
-
Bcl-2 heterodimerises in vivo with a conserved homolog, Bax, that accelerates programmed cell death
-
Z. N. Oltrvai, C. L. Milliman and S. J. Korsmeyer, Bcl-2 heterodimerises in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74, 609-619 (1993).
-
(1993)
Cell
, vol.74
, pp. 609-619
-
-
Oltrvai, Z.N.1
Milliman, C.L.2
Korsmeyer, S.J.3
-
21
-
-
0025841809
-
Induction of cmyc oncoprotein and of cellular proliferation by radiation in normal human urothelial cultures
-
C. Mothersill, C. B. Seymour and A. O'Brien, Induction of cmyc oncoprotein and of cellular proliferation by radiation in normal human urothelial cultures. Anticancer Res. II, 1609-1612 (1991).
-
(1991)
Anticancer Res.
, vol.2
, pp. 1609-1612
-
-
Mothersill, C.1
Seymour, C.B.2
O'Brien, A.3
-
22
-
-
0028274587
-
High levels of stable p53 protein and of c-myc in cultured human epithelial tissue after radiation
-
C. Mothersill, C. B. Seymour, J. Harney and T. P. Hennessy, High levels of stable p53 protein and of c-myc in cultured human epithelial tissue after radiation. Radiat. Res. 137, 317-322 (1994).
-
(1994)
Radiat. Res.
, vol.137
, pp. 317-322
-
-
Mothersill, C.1
Seymour, C.B.2
Harney, J.3
Hennessy, T.P.4
-
23
-
-
0028324254
-
Induction of stable p53 and of c-myc overexpression in cultured normal human uroepithelium by radiation and N-nitrosodiethanolamine
-
C. Mothersill, J. Harney and C. B. Seymour. Induction of stable p53 and of c-myc overexpression in cultured normal human uroepithelium by radiation and N-nitrosodiethanolamine. Radiat. Res. 138, 93-98 (1994).
-
(1994)
Radiat. Res.
, vol.138
, pp. 93-98
-
-
Mothersill, C.1
Harney, J.2
Seymour, C.B.3
-
24
-
-
0028960552
-
Primary explants of normal human uroepithelium show an unusual response to low doses of cobalt-60 gamma rays
-
C. Mothersill, J. Harney, F. Lyng, D. Cottell and C. B. Seymour. Primary explants of normal human uroepithelium show an unusual response to low doses of cobalt-60 gamma rays. Radiat. Res. 142, 177-183 (1995).
-
(1995)
Radiat. Res.
, vol.142
, pp. 177-183
-
-
Mothersill, C.1
Harney, J.2
Lyng, F.3
Cottell, D.4
Seymour, C.B.5
-
25
-
-
0003130940
-
In vitro transformation and tumour progression: A multistep model for skin carcinogenesis
-
M. Leigh, B. Lane and F. M. Watt, Eds. Cambridge University Press, Cambridge, UK
-
P. Boukamp, D. Breitkreutz, A. Hulsen, P. Tomakidi and N. E. Fusenig, In vitro transformation and tumour progression: a multistep model for skin carcinogenesis. In The Keratinocyte Handbook (M. Leigh, B. Lane and F. M. Watt, Eds.), pp. 485-499. Cambridge University Press, Cambridge, UK, 1994.
-
(1994)
The Keratinocyte Handbook
, pp. 485-499
-
-
Boukamp, P.1
Breitkreutz, D.2
Hulsen, A.3
Tomakidi, P.4
Fusenig, N.E.5
-
26
-
-
0026642195
-
Induction of apoptosis in fibroblasts by c-myc protein
-
G. I. Evan, A. H. Wyllie, C. S. Gilbert, T. D. Littlewood, H. Land, M. Brooks, C. M. Waters, L. Z. Penn and D. C. Hancock, Induction of apoptosis in fibroblasts by c-myc protein. Cell 69, 119-128 (1992).
-
(1992)
Cell
, vol.69
, pp. 119-128
-
-
Evan, G.I.1
Wyllie, A.H.2
Gilbert, C.S.3
Littlewood, T.D.4
Land, H.5
Brooks, M.6
Waters, C.M.7
Penn, L.Z.8
Hancock, D.C.9
-
27
-
-
0026667219
-
Role for cmyc in activation-induced apoptotic cell death in T cell lymphomas
-
Y. Shi, J. M. Glynn, L. J. Guilbert, T. G. Cotter, R. P. Bissonette and D. R. Green, Role for cmyc in activation-induced apoptotic cell death in T cell lymphomas. Science 257, 212-214 (1992).
-
(1992)
Science
, vol.257
, pp. 212-214
-
-
Shi, Y.1
Glynn, J.M.2
Guilbert, L.J.3
Cotter, T.G.4
Bissonette, R.P.5
Green, D.R.6
-
28
-
-
0027892521
-
Bcl-2 protein inhibits etoposide-induced apoptosis through its effects on events subsequent to topoisomerase II-induced DNA strand breaks and their repair
-
S. Kamasaki, H. Kamasaki, T. J. Jorgensen, A. Tanizawa, Y. Pommier and J. Cossman, Bcl-2 protein inhibits etoposide-induced apoptosis through its effects on events subsequent to topoisomerase II-induced DNA strand breaks and their repair. Cancer Res. 53, 4251-4256 (1993).
-
(1993)
Cancer Res.
, vol.53
, pp. 4251-4256
-
-
Kamasaki, S.1
Kamasaki, H.2
Jorgensen, T.J.3
Tanizawa, A.4
Pommier, Y.5
Cossman, J.6
-
29
-
-
1842268914
-
Evidence of delayed apoptosis in the distant progeny of two cell lines following ionizing radiation
-
in press
-
F. Lyng, S. O'Reilly, C. B. Seymour, D. Cottell and C. Mothersill, Evidence of delayed apoptosis in the distant progeny of two cell lines following ionizing radiation. Radiat. Environ. Biophys., in press.
-
Radiat. Environ. Biophys.
-
-
Lyng, F.1
O'Reilly, S.2
Seymour, C.B.3
Cottell, D.4
Mothersill, C.5
-
31
-
-
0029680195
-
Radiation-induced chromosomal instability in human mammary epithelial cells
-
M. Durante, G. F. Grossi and T. C. Yang. Radiation-induced chromosomal instability in human mammary epithelial cells. Adv. Space Res. 18, (1/2)99-(1/2)108 (1996).
-
(1996)
Adv. Space Res.
, vol.18
, pp. 1299-12108
-
-
Durante, M.1
Grossi, G.F.2
Yang, T.C.3
-
32
-
-
0027944957
-
Bcl-2 protein expression and long-term survival in breast cancer
-
H. Joensuu, L. Pylkkanen and S. Toikkanen, Bcl-2 protein expression and long-term survival in breast cancer. Am. J. Pathol. 145, 1191-1198 (1994).
-
(1994)
Am. J. Pathol.
, vol.145
, pp. 1191-1198
-
-
Joensuu, H.1
Pylkkanen, L.2
Toikkanen, S.3
-
33
-
-
0023786047
-
Bcl-2 gene promotes haemopoeitic cell survival and cooperates with c-myc to immortalise pre-B cells
-
D. L. Vaux, S. Cory and J. M. Adams, Bcl-2 gene promotes haemopoeitic cell survival and cooperates with c-myc to immortalise pre-B cells. Nature 335, 440-442 (1988).
-
(1988)
Nature
, vol.335
, pp. 440-442
-
-
Vaux, D.L.1
Cory, S.2
Adams, J.M.3
-
34
-
-
0027186201
-
Bcl-2 protein in non-small-cell lung cancer
-
F. Pezzella, H. Turley, I. Kuzu, M. F. Tungekar, A. Harris and D. F. Mason, Bcl-2 protein in non-small-cell lung cancer. N. Engl. J. Med. 329, 690-694 (1993).
-
(1993)
N. Engl. J. Med.
, vol.329
, pp. 690-694
-
-
Pezzella, F.1
Turley, H.2
Kuzu, I.3
Tungekar, M.F.4
Harris, A.5
Mason, D.F.6
-
35
-
-
0028933987
-
A predictive assay for individual patient response of esophageal carcinoma to chemoradiotherapy
-
M. Sheridan, I. Reid, C. Mothersill and C. B. Seymour, A predictive assay for individual patient response of esophageal carcinoma to chemoradiotherapy. J. Exp. Clin. Cancer Res. 14, 74-75 (1995).
-
(1995)
J. Exp. Clin. Cancer Res.
, vol.14
, pp. 74-75
-
-
Sheridan, M.1
Reid, I.2
Mothersill, C.3
Seymour, C.B.4
-
36
-
-
0027421045
-
Role of the p53 tumor suppressor gene in cell cycle arrest and radiosensitivity of Burkitt's lymphoma cell lines
-
P. M. O'Connor, J. Jackman and D. Jondle, Role of the p53 tumor suppressor gene in cell cycle arrest and radiosensitivity of Burkitt's lymphoma cell lines. Cancer Res. 53, 4776-4780 (1993).
-
(1993)
Cancer Res.
, vol.53
, pp. 4776-4780
-
-
O'Connor, P.M.1
Jackman, J.2
Jondle, D.3
-
37
-
-
0028891122
-
p53 expression in urothelium from normal and tumour bearing patients
-
J. Harney, D. Murphy, M. Jones and C. Mothersill, p53 expression in urothelium from normal and tumour bearing patients. Br. J. Cancer 71, 25-29 (1995).
-
(1995)
Br. J. Cancer
, vol.71
, pp. 25-29
-
-
Harney, J.1
Murphy, D.2
Jones, M.3
Mothersill, C.4
-
38
-
-
0025639158
-
The E6 oncoprotein encoded by human papilloma virus types 16 and 18 promotes the degradation of p53
-
M. Scheffner, B. A. Werness, J. M. Huibregtse, A. J. Levine and P. M. Howley, The E6 oncoprotein encoded by human papilloma virus types 16 and 18 promotes the degradation of p53. Cell 63, 1129-1136 (1990).
-
(1990)
Cell
, vol.63
, pp. 1129-1136
-
-
Scheffner, M.1
Werness, B.A.2
Huibregtse, J.M.3
Levine, A.J.4
Howley, P.M.5
-
39
-
-
0027109075
-
p53, guardian of the genome
-
[News]
-
D. P. Lane, p53, guardian of the genome. Nature 358, 15-16 (1992). [News]
-
(1992)
Nature
, vol.358
, pp. 15-16
-
-
Lane, D.P.1
-
40
-
-
0027717832
-
The bcl-2 oncogene: Apoptosis and neoplasia
-
T. J. McDonnell, M. C. Marin and B. Hsu, The bcl-2 oncogene: Apoptosis and neoplasia. Radiat. Res. 136, 307-312 (1993).
-
(1993)
Radiat. Res.
, vol.136
, pp. 307-312
-
-
McDonnell, T.J.1
Marin, M.C.2
Hsu, B.3
-
41
-
-
0027176479
-
p53 mutation does not correlate with radiosensitivity in 24 head and neck cancer cell lines
-
D. G. Brachman, M. Beckett, D. Graves, D. Haraf, E. Yokes and R. R. Weichselbaum, p53 mutation does not correlate with radiosensitivity in 24 head and neck cancer cell lines. Cancer Res. 53, 3667-3669 (1993).
-
(1993)
Cancer Res.
, vol.53
, pp. 3667-3669
-
-
Brachman, D.G.1
Beckett, M.2
Graves, D.3
Haraf, D.4
Yokes, E.5
Weichselbaum, R.R.6
-
42
-
-
1842273747
-
Induction of a high degree of clonal genetic instability in p53 at sites in cultures of normal human uroepithelium exposed to low-dose gamma radiation
-
[Abstract]
-
S. Colucci, C. Mothersill, J. Harney, S. Gamble, C. Seymour, K. Parsons and J. Arrand, Induction of a high degree of clonal genetic instability in p53 at sites in cultures of normal human uroepithelium exposed to low-dose gamma radiation. Br. J. Cancer 71 (Suppl. XXIV), 26 (1995). [Abstract]
-
(1995)
Br. J. Cancer
, vol.71
, Issue.SUPPL. XXIV
, pp. 26
-
-
Colucci, S.1
Mothersill, C.2
Harney, J.3
Gamble, S.4
Seymour, C.5
Parsons, K.6
Arrand, J.7
|