Vanadium-mediated suppression of diethylnitrosamine-induced chromosomal aberrations in rat hepatocytes and its correlation with induction of hepatic glutathione and glutathione S-transferase

International Journal of Oncology

Volumn 10, Issue 2, 1997, Pages 413-423

  Bishayee, Anupam ^a   Banik, Sarmistha ^a   Mandal, Animesh ^a   Marimuthu, P ^a   Chatterjee, Malay ^a  

^a JADAVPUR UNIVERSITY   (India)

Author keywords

anticlastogenic effect; chromosomal abberations; diethylnitrosamine; glutathione; glutathione S transferase; micronucleus test; mitotic index; vanadium

Indexed keywords

GLUTATHIONE; GLUTATHIONE TRANSFERASE; VANADIUM;

ANIMAL EXPERIMENT; ARTICLE; CARCINOGENESIS; CELL PROTECTION; CHROMOSOME ABERRATION; ENZYME INDUCTION; ERYTHROCYTE; LIVER CELL; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0031055984     PISSN: 10196439     EISSN: None     Source Type: Journal    
DOI: 10.3892/ijo.10.2.413     Document Type: Article

References (48)

1. French RJ and Jones PJ: Role of vanadium in nutrition: metabolism, essentiality and dietary consideration. Life Sci 52: 339-346, 1993.
2. Crans DC, Bunch RJ and Theisen LA: Interaction of trace levels of vanadium (IV) and vanadium (V) in biological systems. J Am Chem Soc 111: 7597-7607, 1989.
3. Köpf-Maier P: Cytostatic non-platinum metal complexes: new perspective for the treatment of cancer? Naturwissenschaften 74: 374-382, 1987.
4. Kingsnorth AN, Lamuraglia GM, Ross JS and Malt RA: Vanadate supplements and 1,2-dimethylhydrazine induced colon cancer in mice: increased thymidine incorporation without enhanced carcinogenesis. BrJ Cancer 53: 683-686, 1986.
5. Djordjevic C and Wampler GL: Antitumor activity and toxicity of peroxo heteroligand vanadates (V) in relation to biochemistry of vanadium. J Inorg Biochem 25: 51-55, 1985.
6. Köpf-Maier P and Köpf H: Transition and main-group metal cyclopentadienyl complexes: preclinical studies on a series of antitumor agents of different structural type. Struct Bound 70: 103-185, 1988.
7. Murthy MS, Rao LN, Kuo LY, Toney JH and Marks TJ: Antitumor and toxicologic properties of the organometallic anticancer agent vanadocene dichloride. Inorg Chim Acta 152: 117-124, 1988.
8. Thompson HJ, Chasteen ND and Meeker LD: Dietary vanadyl (IV) sulfate inhibits chemically-induced mammary carcinogenesis. Carcinogensis 5: 849-851, 1984.
9. Hanauske U, Hanauske AR, Marshall MH, Muggia VA and Von Hoff DD: Diphasic effect of vanadium salts on in vitro tumor colony growth. Int J Cell Cloning 5: 170-178, 1987.
10. Köpf-Maier P: Complexes of metals other than platinum and antitumour agents. Eur J Clin Pharmacol 47: 1-16, 1994.
11. Iwai K, Kimura S, Ido T and Iwata R: Tumor uptake of [48V] vanadyl-chlorione e6Na as a tumor-imaging agent in tumor-bearing mice. Int J Radiat Appl Instrum 17: 775-780, 1990.
12. Kachinskas DJ, Phillips MA, Qin Q, Stokes JD and Rice RH: Arsenate perturbation of human keratinocyte differenatiation. Cell Growth Differ 5: 1235-1241, 1994.
13. Sakurai H, Tamura H and Okatani K: Mechanism for a new antitumor vanadium complex: hydroxyl radical dependent DNA cleavage by 1,10-phenanthroline-vanadyl complex in the presence of hydrogen peroxide. Biochem Biophys Res Commun 206: 133-137, 1995.
14. Sardar S, Ghosh R, Mondai A and Chatterjee M: Protective role of vanadium in the survival of hosts during the growth of a transplantable murine lymphoma and its profound effects on the rates and patterns of biotransformation. Neoplasma 40: 27-30, 1993.
15. Sardar S and Chatterjee M: Vanadium: a possible role in the protection of host cells bearing transplantable murine lymphoma. Tumor Res 18: 51-61, 1993.
16. Chakraborty A and Chatterjee M: Enhanced erythropoietin and suppression of γ-glutamyl transpeptidase (GGT) activity in murine lymphoma following administration of vanadium. Neoplasma 41: 291-296, 1994.
17. Bishayee A and Chatterjee M: Inhibition of altered liver cell foci and persistent nodule growth by vanadium during diethylnitrosamine-induced hepatocarcinogenesis in rats. Anticancer Res 15: 455-462, 1995.
18. Bishayee A and Chatterjee M: Inhibitory effect of vanadium on rat liver carcinogenesis initiated with diethylnitrosamine and promoted by phenobarbital. Br J Cancer 71: 1214-1220, 1995.
19. Bishayee A, Karmakar R, Mandai A and Chatterjee M: Vanadium-mediated chemoprotection aganist chemical rat hepatocarcinogenesis: reflection in haematological and histological characteristics. Eur J Cancer Prev (In press).
20. Grover S and Fisher P: Cytogenetic studies in Sprague-Dawley rats during the administration of a carcinogenic nitroso compound-diethylnitrosamine. Eur J Cancer 7: 77-82, 1971.
21. Bishayee A and Chatterjee M: Time course effect of vanadium supplement on cytosolic reduced glutathione level and glutathione S-transferase activity. Biol Tr Elem Res 48: 275-285, 1995.
22. Horiuchi T, Ito K, Suzuki M and Umeda M: Sensitive induction of chromosome aberrations in the in vivo liver cells of 41 rats by N-nitrosodiethylamine. Mutat Res 140: 181-185, 1984.
23. Sarkar A, Mukherjee B, Rana M and Chatterjee M: Comperative patterns of hepatic drug metabolizing enzymes and their possible correlation with chromosomal aberrations in transplantable murine lymphoma: a time course study. Cancer Invest 12: 477-483, 1994.
24. Tates AD, Neuteboon I, Hofler M and den Engeise L: A micronucleus technique for detecting clastogenic effects of mutagens/ carcinogens (DEN, DMN) in hepatocytes of rat liver in vivo. Mutat Res 74: 11-20, 1980.
25. Schmid W: The micronucleus test for carcinogenetic analysis. In: Chemical Mutagens: Principles and Methods for their Detection. Hollaender A (ed). Plenum Press, New York, pp31-53, 1976.
26. MacGregor J, Heddle J, Hite M, Margolin B, Ramel C, Salamone M, Tice R and Wild D: Guidelines for the conduct of micronucleus assay in mammalian bone marrow erythrocytes. Mutat Res 189: 103-112, 1987.
27. . Ellman GL: Tissue sulfhydryl groups. Arch Biochem Biophys 82: 70-77, 1959.
28. Habig WH, Pabst MJ and Jakoby WB: Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. J Biol Chem 249: 7130-7139, 1974.
29. Lowry OH, Rosebrough NJ, Farr AL and Randall RJ: Protein measurement with Folin phenol reagent. J Biol Chem 193: 265-275, 1951.
30. Chasseaud LF: The role of glutathione and glutathione S-transferase in the metabolism of chemical carcinogens and other electrophilic agents. Adv Cancer Res 29: 175-274, 1979.
31. Chatterjee A and Jacob-Raman M: Modifying effect of reduced glutathione on X-ray induced chromosome aberration and cell cycle delay in muntjac lymphocytes in vitro. Mutat Res 175: 73-82, 1986.
32. Nyandieka HS, Wakhisi J and Kilonzo M: Microsomal enzyme activity by dietary constituents. East Afr Med J 66: 796-803, 1989.
33. Shklar G, Schwartz J, Trickler D and Cheverie SR: The effectiveness of mixture of β-carotene, α-tocopherol, glutathione and ascorbic acid for cancer prevention. Nutr Cancer 20: 145-151, 1993.
34. Gopalan-Kriczky P, Hiruma S and Lotlikar PD: Effect of glutathione levels on aflatoxin B1-DNA binding in livers and kidneys of male rats and hamsters pretreated with buthionine sulfoximine and diethylmaleate. Cancer Lett 76: 25-30, 1994.
35. 1-glutathione conjugation in isolated hepatocytes from rats. Cancer Res 49: 1357-1360, 1989.
36. Abu-Zeid A, Staiano N, Yamazoe Y and Kato R: Enhancement by cysteinyl thiols of acetyltransferase-mediated, but not of sulfotransferase-mediated, binding of a pyrolysate-derived N-hydroxyl-amine, 2-hydroxy-amino-6-methyldipyridol[1,2-a:3′,2′-d] imidazole, to DNA. Jpn J Cancer Res 81: 653-659, 1990.
37. Sabbioni E, Pozzi G, Pintar A, Casella L and Garattini S: Cellular retention, cytotoxicity and morphological transformation by vanadium (IV) and vanadium (V) in BALB/3T3 cell lines. Carcinogenesis 12: 47-52, 1991.
38. Sabbioni E, Pozzi G, Devos S, Pintat A, Casella L and Fischbach M: The intensity of vanadium (V)-induced cytotoxicity and morphological transformation in BALB/3T3 cells is dependent on glutathione-dependent bioreduction to vanadium (IV). Carcinogenesis 14: 2565-2568, 1993.
39. . Atkin WB: Nonrandom chromosomal changes in human neoplasia. In: Eukaryotic Chromosome. Structural and Functional Aspects. Socete RC and Obe G (eds). Narosa Publishing House, New Delhi, pp102-129, 1991.
40. Dave BJ, Hsu TC, Hong WK and Pathak S: Nonrandom distribution of mutagen-induced chromosome breaks in lymphocytes of patients with different malignancies. Int J Oncol 5: 733-740, 1994.
41. Wagner ED and Plewa MJ: Induction of somatic mutations in tradescantia clone 4430 by three phenylenediamine isomers and the antimutagenic mechanisms of diethyldithiocarbamate and ammnium meta-vanadate. Mutat Res 306: 165-172, 1994.
42. Mavournin KH, Blakey DH, Cimino MC, Salamone MF and Heddle JA: The in vivo micronucleus assay in mammalian bone marrow and periferal blood. A report of the US Environmental Protection Agency genetox program. Mutat Res 239: 29-80, 1990.
43. Wattenberg LW: Inhibition of carcinogenesis by minor dietary constituents. Cancer Res 52: 2085-2091, 1992.
44. Nijhoff WA, Groen GM and Peters WHM: Induction of rat hepatic and intestinal glutathione S-transferases and glutathione by dietary naturally occurring anticarcinogens. Int J Oncol 3: 1131-1139, 1993.
45. Benson AM, Cha YN, Bueding E, Heine HS and Talalay P: Elevation of extrahepatic glutathione S-transferase activities and epoxide hydratase activities by 2-(3)-tert-butyl-4-hydroxyanisole. Cancer Res 39: 2971-2977, 1979.
46. Sparnins VL, Venegas PL and Wattenberg LW: Glutathione S-tranferase activity enhancement by compounds inhibiting chemical carcinogenesis and by dietary constituents. J Natl Cancer Inst 68: 493-496, 1982.
47. Friedberg EC, Ehmann UK and Williams JI: Human diseases associated with defective DNA repair. Adv Radiat Biol 8: 85-174, 1979.
48. Kihlman BA, Hansson K and Andersson HC: The effects of post-treatments with caffeine during S and Gon the frequencies of chromosomal aberrations induced by thiotepa in root tips of Vicia fava. Environ Exp Bot 20: 271-286, 1982.