Radiation therapy and chemotherapy in the conservative treatment of carcinoma of the anal canal: Survival and late morbidity in a series of 25 patients

Anticancer Research

Volumn 17, Issue 1 B, 1997, Pages 653-656

  Gabriele, Anna Maria ^a   Rovea, Paolo ^a   Sola, Barbara ^a   Trotti, Alessandro Boidi ^a   Comandone, Alessandro ^a  

^a MOLINETTE HOSPITAL   (Italy)

Author keywords

Anal cancer; Chemotherapy; Late effects; Radiotherapy; Survival

Indexed keywords

CARBOPLATIN; FLUOROURACIL; MITOMYCIN C;

ADULT; AGED; ANGINA PECTORIS; ANUS CARCINOMA; ARTICLE; CANCER CONTROL; CANCER REGRESSION; CANCER SURVIVAL; CLINICAL ARTICLE; CONSERVATIVE TREATMENT; DIARRHEA; FEMALE; HUMAN; HUMAN TISSUE; INCIDENCE; INTRAVENOUS DRUG ADMINISTRATION; LEUKOPENIA; MALE; MORBIDITY; PRIORITY JOURNAL; REMISSION; SURVIVAL RATE; SYMPTOM;

AGED; AGED, 80 AND OVER; ANTINEOPLASTIC AGENTS; ANUS NEOPLASMS; CARCINOMA, BASAL CELL; CARCINOMA, MUCOEPIDERMOID; CARCINOMA, SQUAMOUS CELL; COMBINED MODALITY THERAPY; DISEASE-FREE SURVIVAL; FEASIBILITY STUDIES; FEMALE; HUMANS; MALE; MIDDLE AGED; RADIOTHERAPY;

EID: 0031055965     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Boman BM, Moertel CG, O'Connell MJ et al: Carcinoma of the anal canal: a clinical and pathological study of 188 cases. Cancer 54: 114-125, 1984.
2. Brown DK, Oglesby AB, Scott DH et al: Squamous cell carcinoma of the anus: a twenty-five years retrospective. Am Surg 54: 337-342, 1988.
3. Budach V: Therapy of the anal cancer. In: Second International Conference on Biology, Prevention and Treatment of Gastrointestinal Malignancies, Kohln, Germany, 9-12 January, 1995, p 28.
4. Cummings BJ: The place of radiation therapy in the treatment of carcinoma of the anal canal. Cancer Treat Rev 9: 125-147, 1982.
5. Cummings BJ, Keane TJ, O'Sullivan B et al: Epidermoid anal cancer: treatment by radiation alone or by radiation and 5-Fluorouracil with and without Mitomicin C. Int J Radiat Oncol Biol Phis 21: 1115-1125, 1991.
6. Cummings BJ, Keane TJ, Thomas GM et al: results and toxicity of the treatment of the anal carcinoma by radiotherapy or radiation therapy and chemotherapy: Cancer 54: 2062-2068, 1984.
7. Doci R, Zucali R, Bombelli L et al: Combined chemotherapy for anal cancer: report of 56 cases. An Surg 215: 150-156, 1992.
8. Doggett SW, Green JP, Cantril ST: Efficacy of radiation therapy alone for limited squamous cell carcinoma of the anal canal. Int J Radiat Oncol Biol Phys 15: 1069-1072, 1988.
9. Gordon PH: Squamous-cell carcinoma of the anal canal. Surg Clin North Am 68: 1391-1399, 1988.
10. Hermanek P, Sobin LH-Union Internationale Contre le Cancer: TNM classification of malignant tumors. Fourth edition, Springer Verlag, Berlin, 50-52, 1987.
11. Martenson JA, Gundreson LL: External radiation therapy without chemotherapy in the management of the anal cancer. Cancer 5: 1736-1740, 1943.
12. Meeker WR, Sickle-Santanelllo BJ, Phitpott G et al: Combined chemotherapy, radiation and surgery for epithelial cancer of the anal canal. Cancer 57: 354-356, 1974.
13. Nigro ND, Vaitkrvicius YK, Considine B jr: Combined therapy for cancer of the anal canal: a preliminary repor. Dis Colon Rectum 17: 354-356, 1974.
14. Papillon J, Mont barbon JF: Epidermoid Carcinoma of the anal canal, A series of 276 cases. Dis Colon Rectum 30: 324-333, 1987.
15. Salmon RJ, Fenton J, Asselain B et al: Treatment of the epidermoid anal canal cancer. Am J Surg 147: 43-48, 1984.
16. Secco GB, Sertoli MR, Scarpati D et al: Preoperative chemotherapy and radiotherapy in the management of epidermoid carcinoma of the anal canal. Tumori 73: 151-155, 1987.
17. Shank B: Treatment of the anal carcinoma. Cancer 55: 2156-2162, 1985.
18. Sischy B, Remington JH, Hinson EJ et al: Definitive treatment of the anal canal carcinoma by means of radiation therapy and chemotherapy. Dis Colon Rectum 25: 685-688, 1982.
19. Tanum G, Tveit K, Karlsen KO et al: Chemotherapy and radiation for anal carcinoma. Cancer 67: 2462-2466, 1991.
20. Touboul E, Schlienger M, Buffat L et al: Epidermoid carcinoma of the anal canal. Results of curative intent radiation therapy in a series of 270 patients. Cancer 73: 1569-1579, 1994.
21. Wagner JP, Mahe MA, Romestaing P et al: Radiation therapy in the conservative treatment of carcinoma of the anal canal. Int J Radiat Oncol Biol Phys 29: 17-23, 1994.
22. Welch JP, Malr RA: Appraisal of the treatment of the anus and canal. Surg Ginecol Obstet 45: 837-841, 1977.
23. Zelnick RS, Haas PA, Ajlouni M et al: Results of abdominoperineal resections for failures after combination chemotherapy and radiation therapy for the anal canal cancers. Dis Colon Rectum 35: 574-578, 1992.
24. Zucali R, Doci R, Bombelli L: Combined chemotherapy-radiotherapy for the anal cancer. Int J Radiat Oncol Biol Phys 19: 1221-1223, 1990.
25. Zucali R, Doci R, Montaldo F et al: Combined chemoradiation for anal cancer. Atti del XV corso AIOM, Editori Beretta et al, Milano 26-29 giugno 1994. pp 183-194.