Vascular Angiotensin-Converting Enzyme Expression Regulates Local Angiotensin II

Hypertension

Volumn 29, Issue 1, 1997, Pages 98-104

  Muller, Dominik N ^a   Bohlender, Jurgen ^a   Hilgers, Karl F ^a   Dragun, Duska ^a   Costerousse, Olivier ^a   Menard, Joel ^a   Luft, Friedrich C ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN; DIPEPTIDYL CARBOXYPEPTIDASE; RENIN;

ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME KINETICS; ENZYME SUBSTRATE; GENE EXPRESSION REGULATION; HINDLIMB; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; RENOVASCULAR HYPERTENSION;

ANGIOTENSIN I; ANGIOTENSIN II; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; AORTA; CAPTOPRIL; GENE EXPRESSION; HINDLIMB; HYPERTENSION, RENAL; MALE; PEPTIDYL-DIPEPTIDASE A; PERFUSION; RATS; RATS, SPRAGUE-DAWLEY; RENIN; RNA, MESSENGER;

EID: 0031054639     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/01.HYP.29.1.98     Document Type: Article

References (48)

1. Erdos EG. Angiotensin I converting enzyme and the changes in our concepts through the years. Hypertension. 1990;16:363-370.
2. Johnston CI. Renin angiotensin system: a dual tissue and hormonal system for cardiovascular control. J Hypertens. 1992;10(suppl 7):S13-S20.
3. Vane GR. Sites of conversion of angiotensin I. In: Genest J, Koine N, eds. Hypertension. Berlin, FRG: Springer-Verlag; 1992:1387-1388.
4. Cadwell PR, Segal BC, Hsu KC, Das M, Soffer RL. Angiotensin converting enzyme: vascular endothelial localization. Science. 1976;191:1050-1051.
5. Arnal JF, Battle T, Rasetti C, Challah M, Costerousse O, Vicaut E, Michel JB, Alhenc-Gelas F. ACE in three tunicae of rat aorta: expression in smooth muscle and effect of renovascular hypertension. Am J Physiol. 1994;267:H1777-H1784.
6. Rogerson FM, Chai SY, Schlawe I, Murray WK, Marley PD, Mendelsohn FAO. Presence of angiotensin converting enzyme in the adventitia of large vessels. J Hypertens. 1992;7:615-620.
7. Hilgers KF, Kuczera M, Wilhelm MJ, Wiecek A, Ritz E, Ganten D, Mann JFE. Angiotensin formation in the isolated rat hindlimb. J Hypertens. 1989;7:789-798.
8. Admiraal PJJ, Danser AHL, Jong MS, Pieterman H, Derkx FHM, Schalekamp MADH. Regional angiotensin II production in essential hypertension and renal artery stenosis. Hypertension. 1993;21:173-184.
9. Aiken JW, Vane JR. Inhibition of angiotensin-converting enzyme of the renin-angiotensin system in kidneys and hindlegs of dogs. Circ Res. 1972;30:263-271.
10. Campbell DJ. The site of angiotensin production. J Hypertens. 1985;3:199-207.
11. Britton S, Di Salvo J. Effects of angiotensin I and II on hindlimb and coronary vascular resistance. Am J Physiol. 1973;225:1226-1231.
12. Campbell DJ, Ziogas J, Kladis A. Metabolism of tetradecapeptide, angiotensinogen and angiotensin I and II by isolated perfused rat hindlimbs. Clin Exp Pharmacol Physiol. 1990;17:335-350.
13. Kuczera M, Hilgers KF, Lisson C, Ganten D, Hilgenfeldt U, Ritz E, Mann JFE. Local angiotensin formation in hindlimbs of uremic hypertensive and renovascular hypertensive rats. J Hypertens. 1991;9:41-48.
14. Cambien F, Poirier O, Lecerf L, Evans A, Cambou JP, Arveiler D, Luc G, Bard J-M, Bara L, Ricard S, Tiret L, Amouyel P, Alhenc-Gelas F, Soubrier F. Deletion polymorphism in the gene for ACE is a potent risk factor for myocardial infarction. Nature. 1992;359:641-644.
15. Raynolds MV, Bristow MR, Bush EW, Abraham WT, Lowes BD, Zisman LS, Taft CS, Perryman MB. Angiotensin converting enzyme DD genotype in patients with ischaemic or idiopathic dilatated cardiomyopathy. Lancet. 1993;342:1085-1086.
16. Schunckert H, Hense HW, Holmer SR, Stender M, Perzs S, Keil U, Lorell BH, Rieger GA. Association between a deletion polymorphism of the angiotensin converting enzyme gene and left ventricular hypertrophy. N Engl J Med. 1994;330:1634-1638.
17. Alhenc-Gelas F, Richard J, Courbon D, Warnet JM, Corvol P. Distribution of plasma angiotensin converting enzyme levels in healthy men. J Lab Clin Med. 1991;117:33-39.
18. Niarchos AP, Resnick LM, Weinstein DL, Laragh JH. Angiotensin I converting enzyme activity in hypertension, relationship to blood pressure, renin sodium profiles and antihypertensive treatment. Am J Med. 1985;79:435-444.
19. Rigat B, Hubert C, Alhenc-Gelas F, Cambien F, Corvol P, Soubrier F. An I/D polymorphism in the angiotensin I converting enzyme gene accounting for half the variance of serum enzyme levels. J Clin Invest. 1990;86:1343-1346.
20. Costerousse O, Allegrini J, Lopez M, Alhenc-Gelas F. Angiotensin I converting enzyme in human circulating mononuclear cells: genetic polymorphism of expression in T-lymphocytes. Biochem J. 1993;290:33-40.
21. Ashton JH, Pitt BR, Gillis CN. Apparent kinetics of angiotensin converting enzyme: hydrolysis of [3H]benzoyl-phenylalanyl-alanyl-proline in the isolated perfused lung. J Pharmacol Exp Ther. 1985;232:602-607.
22. Hilbert P, Lindpaintner K, Beckmann JS, Serikawa T, Soubrier F, Dubay C, Cartwright P, Degouyon B, Julier C, Takahasi S, Vincent M, Ganten D, Georges M, Lathrop GM. Chromosomal mapping of two genetic loci associated with blood pressure regulation in hereditary hypertensive rats. Nature. 1991;353:521-529.
23. Hilgers KF, Veelken R, Mai M, Ganten U, Ganten D, Luft FC, Mann JFE. Vascular conversion of angiotensin I in stroke-prone spontaneously hypertensive and Wistar-Kyoto rats. J Hypertens. 1993;11:1053-1059.
24. Fernandez-Alfonso MS, Kreutz R, Zeh K, Liu Y, Ganten D, Paul M. Differential regulation of vascular angiotensin I-converting enzyme in hypertension. Hypertension. 1994;24:280-286.
25. Cushman DW, Cheung MS. Spectrophotometric assay and properties of the angiotensin converting enzyme of rabbit lung. Biochem Pharmacol. 1971;20:1637-1648.
26. Bradford MM. A rapid and sensitive method for the quantification of microgram quantities of protein utilising the principle-dye binding. Anal Biochem. 1976;72:248-254.
27. Menard J, Catt KJ. Measurement of renin activity, concentration and substrate in rat plasma by radioimmunoassay of angiotensin. J Endocrinol. 1972;90:422-430.
28. Auffray C, Rougeon F. Purification of mouse immunoglobulin heavy-chain messenger RNAs from total myeloma tumor RNA. Eur J Biochem. 1980;107:303-314.
29. Costerousse O, Allegrini J, Huang H, Bounhik J, Alhenc-Gelas F. Regulation of ACE gene expression and plasma levels during postnatal development. Am J Physiol. 1994;267:E745-E753.
30. Djavidani B, Sander M, Kreutz R, Zeh K, Bader M, Mellon SH, Vecsei P, Peters J, Ganten D. Chronic dexamethasone treatment suppresses hypertension development in the transgenic rat TGR (mREN2)27. J Hypertens. 1995;13:637-645.
31. Danser AH, Schalekamp MA, Bax WA, van den Brink AM, Saxena PR, Rieger GA, Schunkert H. Angiotensin-converting enzyme in the human heart: effect of the deletion/insertion polymorphism. Circulation. 1995;92:1387-1388.
32. Harden PN, Geddes C, Rowe PA, McIlroy HJ, Boulton-Jones M, Rodger RSC, Junor BJR, Briggs JD, Connell JMC, Jardine AG. Polymorphisms in angiotensin-converting-enzyme gene and progression of IgA nephropathy. Lancet. 1995;345:1540-1542.
33. Jeunemaitre X, Rigat B, Charru A, Houot AM, Soubrier F, Corvol P. Sib pair linkage analysis of renin gene haplotypes in human essential hypertension. Hum Genet. 1992;88:301-306.
34. Soubrier F, Jeunemaitre X, Rigat B, Houot AM, Cambien F, Corvol P. Similar frequencies of renin gene restriction fragment length polymorphisms in hypertensive and normotensive subjects. Hypertension. 1990;16:712-717.
35. Okunishi H, Oka Y, Shiota N, Kawamoto T, Song K, Miyazaki M. Marked species-difference in the vascular angiotensin II-forming pathways: humans versus rodents. Jpn J Pharmacol. 1993;62:207-210.
36. Schunkert H, Dzau VJ, Tang SS, Hirsch AT, Apstein CS, Lorell BH. Increased rat cardiac angiotensin converting enzyme activity and mRNA expression in pressure overload left ventricular hypertrophy: effects on coronary resistance, contractility and relaxation. J Clin Invest. 1990;86:1913-1920.
37. Rakugi H, Kim DK, Krieger JE, Wang DS, Dzau VJ, Pratt RE. Induction of angiotensin converting enzyme in the neointima after vascular injury: possible role in restenosis. J Clin Invest. 1994;93:339-346.
38. Okamura T, Miyazaki M, Inagami T, Toda N. Vascular renin angiotensin system in two kidney, one clip hypertensive rats. Hypertension. 1986;8:560-565.
39. Gasic S, Heinz G, Kleinbloesm C. Quantitative evidence of peripheral conversion of angiotensin within the human leg: effects of local angiotensin I administration and angiotensin converting enzyme inhibition on regional blood flow and angiotensin II balance across the leg. Naunyn Schmiedebergs Arch Pharmacol. 1990;342:436-440.
40. Campbell DJ. Circulating and tissue angiotensin systems. J Clin Invest. 1987;79:1-6.
41. Admiraal PJJ, Derkx FHM, Danser AHJ, Pieterman H, Schalekamp MADH. Metabolism and production of angiotensin I in different vascular beds in subjects with hypertension. Hypertension. 1990;15:44-55.
42. Schalekamp MADH. The renin-angiotensin system: new surprise ahead. J Hypertens. 1991;9(suppl 6):S10-S17.
43. Urata H, Healey B, Stewart RW, Bumpus FM, Husain A. Angiotensin II forming pathways in normal and failing human hearts. Circ Res. 1990;66:883-890.
44. Okunishi H, Miyazaki M, Toda N. Evidence for a putatively new angiotensin II generating enzyme in the vascular wall. J Hypertens. 1984;2:277-284.
45. Miura SI, Ideishi M, Sakai T, Motoyama M, Kinoshita A, Sasaguri M, Tanaka H, Shindo N, Arakawa K. Angiotensin II formation by alternative pathway during exercise in humans. J Hypertens. 1994;12:1177-1181.
46. Michel JB, Dussaule JC, Choudat L, Auzan C, Nochy D, Corvol P, Menard J. Effects of antihypertensive treatment in one clip, two kidney hypertension in rats. Kidney Int. 1985;29:1011-1020.
47. Kato H, Iwai N, Inui H, Kimoto K, Uchiyama Y, Inagami T. Regulation of vascular angiotensin release. Hypertension. 1993;21:446-454.
48. Morishita R, Higaki J, Tomita N, Aoki M, Moriguchi A, Tamura K, Murakami K, Kaneda Y, Ogihara T. Role of transcriptional cis-elements, angiotensinogen gene-activating elements, of angiotensinogen gene in blood pressure regulation. Hypertension. 1996;27[pt 2]:502-507.