Changes in tumor oxygenation during a combined treatment with fractionated irradiation and hyperthermia: An experimental study

International Journal of Radiation Oncology Biology Physics

Volumn 37, Issue 1, 1997, Pages 155-162

  Zywietz, Friedrich ^a   Reeker, Wolfram ^b   Kochs, Eberhard ^b  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Fractionated irradiation and hyperthermia; pO2 measurements; Rat rhabdomyosarcoma; Tumor oxygenation

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ARTIFICIAL VENTILATION; BLOOD GAS ANALYSIS; CONTROLLED STUDY; CYTOTOXICITY; HYPERTHERMIA; IRRADIATION; NONHUMAN; OXYGEN TENSION; PRIORITY JOURNAL; RADIATION DOSE FRACTIONATION; RADIOSENSITIZATION; RAT; RHABDOMYOSARCOMA; TUMOR BLOOD FLOW;

ANIMALS; COMBINED MODALITY THERAPY; HYPERTHERMIA, INDUCED; MALE; NEOPLASM TRANSPLANTATION; NEOPLASMS; OXYGEN; PARTIAL PRESSURE; RADIOTHERAPY DOSAGE; RATS; RHABDOMYOSARCOMA;

EID: 0031054056     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0360-3016(96)00465-8     Document Type: Article

References (39)

1. Arcangeli, G.; Giovinazzo, G.; Saracino, B.; Begnozzi, L. Prognostic parameters in combined hyperthermia and ra-diotherapy. In: Gerner, E. W.; Cetas, T. C., eds. Hyperthermic oncology 1992, Tucson: Arizona Board of Regents; 1993:339-343.
2. Badylak, S. F.: Babbs, C. F.; Skojac, T. M.; Voorhees, W. D.; Richardson, R. C. Hyperthermia-induced vascular injury in normal and neoplastic tissue. Cancer 56:991-1000; 1985.
3. Engin, K.; Tupchong, L.; Waterman, F. M.; Cater, J. R.; Koppel, A.; Dietz, D.; Hoh, L.; McFarlane, J. D.; Leeper. D. B. Thermoradiotherapy for superficial tumor deposits in the head and neck. Int. J. Hyperthermia 10:153-164: 1994.
4. ESHO 1994, Proceedings of the Joint Meeting of the European Societies for Radiation Biology ESRB and Hyperthermic Oncology, Amsterdam, The Netherlands, June 1-4, 1994.
5. Fajardo, L. F.; Prionas, S. D. Endothelial cells and hyperthermia. Int. J. Hyperthermia 10:347-353; 1994.
6. Fleckenstein, W.; Jungblut, J. R.; Suckfüll, M. Distribution of oxygen pressure in the periphery and centre of malignant head and neck tumors. In: Ehrly, A. M.; Fleckenstein, W.; Hauss, J.; Huch, R., eds. Clinical oxygen pressure measurement. II. Berlin: Blackwell Ueberreuter; 1990:81-90.
7. Gatenby, R. A.; Kessler, H. B.; Rosenblum, J. S.; Coia, L. R.; Moldofsky, P. J.; Hartz, W. H.; Broder, G. J. Oxygen distribution in squamous cell carcinoma metastases and its relationship to outcome of radiotherapy. Int. J. Radiat. Oncol. Biol. Phys. 14:831-838; 1988.
8. Jung, H.; Krüger, H. J.; Brammer, I.; Zywietz, F.; Beck-Bornholdt, H. P. Cell population kinetics of the rhabdomyosarcoma R1H of the rat after single doses of X-rays. Int. J. Radiat. Biol. 57:567-589; 1990.
9. Kapp, D. S. Thermoradiotherapy of local-regional recurrences of breast cancer: Treatment techniques, prognostic parameters, and future directions. In: Gerner, E. W.; Cetas, T. C., eds. Hyperthermic oncology 1992. Tucson: Arizona Board of Regents: 1993:321-324.
10. Kelleher, D. K.; Engel, T.; Vaupel, P. W. Changes in microregional perfusion, oxygenation, ATP and lactate distribution in SC rat tumors upon water-filtered IR-A-hyperthermia. Int. J. Hyperthermia 11:241-255; 1995.
11. Mäntylä, M.; Toivanen, J. T.; Pitkänen, M. A.; Rekonen, A. H. Radiation-induced changes in regional blood flow in human tumours. Int. J. Radiat. Oncol. Biol. Phys. 8:1711-1717; 1982.
12. Mooibroek, J.; Dikoiney, E.; Zywietz, F.; Jung, H. Therinotolerance kinetics and growth rate changes in the R1H tumour heated at 43°C. Int. J. Hyperthermia 4:677-686; 1988.
13. Onishi, T.; Machida, T.; Iizuka, N.; Nakauchi, K.; Shirakawa, H.; Masuda, F.; Mochizuki, S.; Tsukamoto, H.; Harada, N. Influence of differences in tumor vascularity upon the effects of hyperthermia. Urol. Res. 18:313-318; 1990.
14. Overgaard, J. The current and potential role of hyperthermia in radiotherapy. Int. J. Radiât. Oncol. Biol. Phys. 16:535-549; 1989.
15. Rappaport, D. S.; Song, C. W. Blood flow and intravascular volume of mammary adenocarcinoma 13726A and normal tissues of rat during and following hyperthermia. Int. J. Radiat. Oncol. Biol. Phys. 9:539-547; 1983.
16. 2) in a rat rhabdomyosarcoma: A methodical study. In: Vaupel, P.; Kelleher, D. K.; Günderoth, M., eds. Tumor oxygenation. Stuttgart: Fischer Verlag; 1995:59-72.
17. Reinhold, H. S.; Endrich, B. Tumor microcirculation as a target for hyperthermia. Int. J. Hyperthermia 2:111-137; 1986.
18. Reinhold, H. S.; Hopwell, J. W.; Calvo, W.; Keyeux, H.; Reyners, H. Vasculoconnective tissue. In: Scherer, E.; Streffer, C.; Trott, K. R., eds. Radiopathology of organs and tissues. Berlin: Springer Verlag; 1991:243-268.
19. Reinhold, H. S.; van den Berg-Block, A. E. Differences in the response of the microcirculation to hyperthermia in five different tumours. Eur. J. Cancer Clin. Oncol. 25:611-618; 1989.
20. Reinhold, H. S.; van den Berg-Block, A. E. Heat-induced microcirculatory stoppage strongly enhances tumour control by radiation. In: Overgaard, J., ed. Hyperthermic oncology 1984. London and Philadelphia: Taylor and Francis; 1984:149-152.
21. 2 in well oxygenated xenotransplanted human sarcoma. Int. J. Radiat. Oncol. Biol. Phys. 20:1273-1280; 1991.
22. Song, C. W. Effect of hyperthermia on the blood flow in tumors and normal tissues and vascular adaptation to repeated heatings. In: Gerner, E. W.; Cetas, T. C., eds. Hyperthermic oncology 1992, vol. 2. Tucson: Arizona Board of Regents; 1993:149-151.
23. Song, C. W. Tumor blood flow response to heat. In: Vaupel, P.; Jain, R. K., eds. Tumor blood supply and metabolic microenvironment. Stuttgart: Fischer Verlag; 1991:123-141.
24. Tanaka, Y.; Hasegawa, T.; Murata, T. Effect of irradiation and hyperthermia on vascular function in normal and tumor tissue. In: Overgaard, J., ed. Hyperthermic oncology 1984, vol. 1. London and Philadelphia: Taylor and Francis; 1984:145-148.
25. Tozer, G. M.; Myers, R.; Cunningham, V. J. Radiation-induced modification of blood flow distribution in a rat fibrosarcoma. Int. J. Radiat. Biol. 60:327-334; 1991.
26. Van der Zee, J.; Koper, P. C. M.; van den Berg, A. P. Results of hyperthermia and radiotherapy in recurrent breast cancer. In: Gerner, E. W.; Cetas, T. C., eds. Hyperthermic oncology 1992. Tucson: Arizona Board of Regents; 1993:317-319.
27. Vaupel, P. Effects of physiological parameters on tissue response to hyperthermia: New experimental facts and their relevance to clinical problems. In: Gerner, E. W.; Cetas, T. C., eds. Hyperthermic oncology 1992, vol. 2. Tucson: Arizona Board of Regents; 1993:17-23.
28. Vaupel, P. Pathophysiological mechanisms of hyperthermia in cancer therapy. In: Gautherie, M., ed. Biological basis of oncologic thermotherapy. Berlin: Springer Verlag; 1990:73-134.
29. Vaupel, P.; Kelleher, D. K.; Günderoth, M., eds. Tumor oxygenation. Stuttgart: Fischer Verlag; 1995:1-342.
30. 2 saturation in malignant tumors during normoxia and hyperoxia. Microvasc. Res. 17:181-191; 1979.
31. Vaupel, P. W.; Otte, J.; Manz, R. Oxygenation of malignant tumors after localized microwave hyperthermia. Radiat. Environ. Biophys. 20:289-300; 1982.
32. Wiedemann, G.; Roszinski, S.; Biersack, A.; Weiss, C.; Wagner, T. Local hyperthermia enhances cyclophosphamide, ifosfamide and cis-diamminedichloroplatinum cytotoxicity on human-derived breast carcinoma and sarcoma xenografts in nude mice. J. Cancer Res. Clin. Oncol. 118:129-135; 1992.
33. Zywietz, F. Vascular and cellular damage in a murine tumor during fractionated treatment with radiation and hyperthermia. Strahlenther. Onkol. 166:493-501; 1990.
34. Zywietz, F.; Hahn, L. S.; Lierse, W. Ultrastructural studies on tumor capillaries of a rat rhabdomyosarcoma during fractionated radiotherapy. Acta Anat. 150:80-85; 1994.
35. Zywietz, F.; Knöchel, R. Dielectric properties of Co-y-irradi-ated and microwave-heated rat tumor and skin measured in vivo between 0.2 and 2.4 GHz. Phys. Med. Biol. 31:1021-1029; 1986.
36. Zywietz, F.; Knöchel, R.; Kordts, J. Heating of a rhabdomyosarcoma of the rat by 2450 MHz microwaves: Technical aspects and temperature distributions. Rec. Results Cancer Res. 101:36-46; 1986.
37. Zywietz, F.; König, K.; Lierse, W.; Hahn, L. S. Tissue damage in a rat tumor during fractionated treatment with radiation and hyperthermia: A morphological study. In: Gerner, E. W., ed. Hyperthermic oncology 1992. Tucson: Arizona Board of Regents; 1992:200.
38. Zywietz, F.; Lierse, W. Changes in tumor vasculature under fractionated radiation-hyperthermia treatment. Rec. Results Cancer Res. 107:60-64; 1988.
39. Zywietz, F.; Reeker, W.; Kochs, E. Tumor oxygenation in a transplanted rat rhabdomyosarcoma during fractionated irradiation. Int. J. Radiat. Oncol. Biol. Phys. 32:1391-1400; 1995.