5-HT inhibits calcium current and synaptic transmission from sensory neurons in lamprey

Journal of Neuroscience

Volumn 17, Issue 5, 1997, Pages 1786-1794

  El Manira, Abdeljabbar ^a   Zhang, Weiqi ^a,b   Svensson, Erik ^a   Bussières, Nathalie ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

5 HT; calcium channels; locomotion; modulation; presynaptic inhibition; spinal cord; synaptic transmission

Indexed keywords

ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; CALCIUM CHANNEL; CALCIUM ION; DOPAMINE; SEROTONIN; SEROTONIN 1A RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALCIUM CURRENT; CONTROLLED STUDY; CYCLOSTOME; EXCITATORY POSTSYNAPTIC POTENTIAL; INTERNEURON; LOCOMOTION; NEUROMODULATION; NONHUMAN; PRESYNAPTIC INHIBITION; PRIORITY JOURNAL; SENSORIMOTOR FUNCTION; SEROTONINERGIC SYSTEM; SPINAL CORD; SPINAL GANGLION; SYNAPTIC TRANSMISSION;

EID: 0031053964     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.17-05-01786.1997     Document Type: Article

References (44)

1. Anwyl R (1990) Neurophysiological actions of 5-hydroxytryptamine in the vertebrate nervous system. Prog Neurobiol 35:451-468.
2. Barbeau H, Rossignol S (1990) The effects of serotonergic drugs on the locomotor pattern and on cutaneous reflexes of the adult chronic spinal cat. Brain Res 514:55-67.
3. Bongianni F, Christenson J, Hökfelt T, Grillner S (1990) Neuropeptide Y-immunoreactive spinal neurons make close appositions on axons of primary sensory afferents. Brain Res 523:337-341.
4. Brodin L, Christenson J, Grillner S (1987) Single sensory neurons activate excitatory amino acid receptors in the lamprey spinal cord. Neurosci Lett 75:75-79.
5. Brodin L, Buchanan JT, Hökfelt T, Grillner S, Rehfeld JF, Frey P, Verhofstad AA, Dockray GJ, Walsh JH (1988) Immunohistochemical studies of cholecystokinin-like peptides and their relation to 5-HT, CGRP, and bombesin immunoreactivities in the brainstem and spinal cord of lampreys. J Comp Neurol 271:1-18.
6. Buchanan JT, Grillner S (1991) 5-Hydroxytryptamine depresses reticulospinal excitatory postsynaptic potentials in motoneurons of the lamprey. Neurosci Lett 122:71-74.
7. B receptors in lamprey. J Neurophysiol 66:2141-2149.
8. Christenson J, Franck J, Grillner S (1989) Increase in endogenous 5-hydroxytryptamine levels modulates the central network underlying locomotion in the lamprey spinal cord. Neurosci Lett 100:188-192.
9. Christenson J, Cullheim S, Grillner S, Hökfelt T (1990) 5-Hydroxytryptamine immunoreactive varicosities in the lamprey spinal cord have no synaptic specializations - an ultrastructural study. Brain Res 512:201-209.
10. Christenson J, Bongianni F, Grillner S, Hökfelt T (1991) Putative GABAergic input to axons of spinal interneurons and primary sensory neurons in the lamprey spinal cord as shown by intracellular Lucifer yellow and GABA immunohistochemistry. Brain Res 538:313-318.
11. Christenson J, Shupliakov O, Cullheim S, Grillner S (1993) Possible morphological substrates for GABA-mediated presynaptic inhibition in the lamprey spinal cord. J Comp Neurol 328:463-472.
12. Dale N, Kandel ER (1990) Facilitatory and inhibitory transmitters modulate spontaneous transmitter release at cultured Aplysia sensorimotor synapses. J Physiol (Lond) 421:203-222.
13. 2+ current in excitable cells. Trends Neurosci 19:35-43.
14. 2+ influx in presynaptic facilitation. Nature 361:634-637.
15. Grillner S, Deliagina T, Ekeberg Ö, El Manira A, Hill RH, Lansner A, Orlovsky GN, Wallén P (1995) Neural networks that co-ordinate locomotion and body orientation in lamprey. Trends Neurosci 18:270-279.
16. Harris-Warrick RM, Cohen AH (1985) Serotonin modulates the central pattern generator for locomotion in the isolated lamprey spinal cord. J Exp Biol 116:27-46.
17. Harris-Warrick RM, Marder E (1991) Modulation of neural networks for behavior. Annu Rev Neurosci 14:39-57.
18. Harris-Warrick RM, McPhee JC, Filler JA (1985) Distribution of serotonergic neurons and processes in the lamprey spinal cord. Neuroscience 14:1127-1140.
19. Hille B (1994) Modulation of ion-channel function by G-protein-coupled receptors. Trends Neurosci 17:531-535.
20. Hori Y, Endo K, Takahashi T (1996) Long-lasting synaptic facilitation induced by serotonin in superficial dorsal horn neurones in the rat spinal cord. J Physiol (Lond) 492:867-876.
21. Hounsgaard J, Kiehn O (1989) Serotonin-induced bistability of turtle motoneurones caused by a nifedipine-sensitive calcium plateau potential. J Physiol (Lond) 414:265-282.
22. Jacobs BL, Fornal CA (1993) 5-HT and motor control: a hypothesis. Trends Neurosci 16:346-352.
23. B synaptic potential in rat dopamine neurons. J Neurosci 12:2000-2006.
24. 2. J Neurosci 15:6035-6045.
25. Katz PS, Frost WN (1996) Intrinsic neuromodulation - altering neuronal circuits from within. Trends Neurosci 19:54-61.
26. Katz PS, Getting PA, Frost WN (1994) Dynamic neuromodulation of synaptic strength intrinsic to a central pattern generator circuit. Nature 367:729-731.
27. Matsushima T, Grillner S (1992) Local serotonergic modulation of calcium-dependent potassium channels controls intersegmental coordination in the lamprey spinal cord. J Neurophysiol 67:1683-1690.
28. Mintz I, Korn H (1991) Serotonergic facilitation of quantal release at central inhibitory synapses. J Neurosci 11:3359-3370.
29. Rovainen CM (1967) Physiological and anatomical studies on large neurons of central nervous system of the sea lamprey (Petromyzon marinus). II. Dorsal cells and giant interneurons. J Neurophysiol 30:1024-1042.
30. Sah DWY (1990) Neurotransmitter modulation of calcium current in rat spinal cord neurons. J Neurosci 10:136-141.
31. Saudou F, Hen R (1994) 5-Hydroxytryptamine receptor subtypes in vertebrates and invertebrates. Neurochem Int 25:503-532.
32. Schotland J, Shupliakov O, Wikström M. Brodin L, Srinivasan M, You ZB, Herrera-Marschitz M, Zhang W, Hökfelt T, Grillner S (1995) Control of lamprey locomotor neurons by colocalized monoamine transmitters. Nature 374:266-268.
33. Schotland J, Shupliakov O, Grillner S, Brodin L (1996) Synaptic and nonsynaptic monoaminergic neuron systems in the lamprey spinal cord. J Comp Neurol 372:229-244.
34. Shupliakov O, Pieribone VA, Gad H, Brodin L (1995) Synaptic vesicle depletion in reticulospinal axons is reduced by 5-hydroxytryptamine -direct evidence for presynaptic modulation of glutamatergic transmission. Eur J Neurosci 7:1111-1116.
35. Sillar KT, Simmers AJ (1994a) 5-HT induces NMDA receptor-mediated intrinsic oscillations in embryonic amphibian spinal neurons. Proc R Soc Lond [Biol] 255:139-145.
36. Sillar KT, Simmers AJ (1994b) Presynaptic inhibition of primary afferent transmitter release by 5-hydroxytryptamine at a mechanosensory synapse in the vertebrate spinal cord. J Neurosci 14:2636-2647.
37. Sillar KT, Wedderburn JF, Simmers AJ (1992) Modulation of swimming rhythmicity by 5-hydroxytryptamine during post-embryonic development in Xenopus laevis. Proc R Soc Lond [Biol] 250:107-114.
38. Steinbusch HW, Verhofstad AAJ, Jootsten HWJ (1987) Localization of serotonin in the central nervous system by immunohistochemistry: description of a specific and sensitive technique and some applications. Neuroscience 3:811-819.
39. Umemiya M, Berger AJ (1995) Presynaptic inhibition by serotonin of glycinergic inhibitory synaptic currents in the rat brain stem. J Neurophysiol 73:1192-1200.
40. Van Dongen PA, Hökfelt T, Grillner S, Verhofstad AA, Steinbusch HW, Cuello AC, Terenius L (1985) Immunohistochemical demonstration of some putative neurotransmitters in the lamprey spinal cord and spinal ganglia: 5-hydroxytryptamine-, tachykinin-, and neuropeptide-Y-immunoreactive neurons and fibers. J Comp Neurol 234:501-522.
41. Wallén P, Buchanan JT, Grillner S, Hill RH, Christenson J, Hökfelt T (1989) Effects of 5-hydroxytryptamine on the afterhyperpolarization, spike frequency regulation, and oscillatory membrane properties in lamprey spinal cord neurons. J Neurophysiol 61:759-768.
42. Welsh JH, Moorhead M (1960) The quantitative distribution of 5-hydroxytryptamine in the invertebrates, especially in their nervous system. J Neurochem 6:146-169.
43. 1A-like receptors. Brain Res 678:191-199.
44. Zhang W, Pombal MA, El Manira A, Grillner S (1996) Rostrocaudal distribution of 5-HT innervation in the lamprey spinal cord and differential effects of 5-HT on fictive locomotion. J Comp Neurol 374:278-290.