Serum carcinoembryonic antigen concentration doubling time correlates with tumor biology and life expectancy in patients with recurrent gastrointestinal carcinoma

Archives of Surgery

Volumn 132, Issue 2, 1997, Pages 188-194

  Korenaga, Daisuke ^a,c   Saeki, Hiroshi ^a   Mawatari, Kyotaro ^a   Orita, Hiroyuki ^a   Maekawa, Soichiro ^a   Ikeda, Toshihiko ^a   Sugimachi, Keizo ^b  

^a Fukuoka City Hospital   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c FUKUOKA DENTAL COLLEGE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOEMBRYONIC ANTIGEN;

ADULT; AGED; ARTICLE; BLOOD LEVEL; CANCER GROWTH; CANCER RECURRENCE; CANCER SURVIVAL; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE COURSE; FEMALE; GASTROINTESTINAL CARCINOMA; HUMAN; LIFE EXPECTANCY; MALE; POSTOPERATIVE PERIOD; PRIORITY JOURNAL; PROGNOSIS;

EID: 0031053763     PISSN: 00040010     EISSN: None     Source Type: Journal    
DOI: 10.1001/archsurg.1997.01430260086019     Document Type: Article

References (28)

1. Fletcher RH. Carcinoembryonic antigen. Ann Intern Med. 1986;104:66-73.
2. Martin EW, James KK, Hurtubise PE, et al. The use of CEA as an early indicator for gastrointestinal recurrence and second-look procedures. Cancer. 1977;39:440-446.
3. Wanebo HJ, Stearns M, Schwarz MK. Use of CEA as an indicator of early recurrence and as a guide to a selected second-look procedure in patients with colorectal cancer. Ann Surg. 1978;188:481-493.
4. Tamada R, Hiramoto Y, Tsujitani S, et al. Serum CEA levels facilitate detection of recurrences of cancer in patients after gastrectomy. Jpn J Surg. 1985;15:23-29.
5. Staab HJ, Anderer FA, Stumpf E, et al. Slope analysis of the postoperative CEA time course and its possible application as an aid in diagnosis of disease progression in gastrointestinal cancer. Am J Surg. 1978;136:322-327.
6. Maehara Y, Sugimachi K, Akagi M, et al. Serum carcinoembryonic antigen level increases correlate with tumor progression in patients with differentiated gastric carcinoma following noncurative resection. Cancer Res. 1990;50:3952-3955.
7. Collins VP, Loeffer RK, Tivey H. Observations on growth rates of human tumors. AJR Am J Roentogenol. 1956;76:988-1000.
8. Staab HJ, Anderer FA, Hornung A, et al. Doubling time of circulating CEA and its relation to survival of patients with recurrent colorectal cancer. Br J Cancer. 1982;46:773-781.
9. Havelaar IJ, Sugarbaker PH, Vermess M, et al. Role of growth of intraabdominal metastases from colorectal cancer. Cancer. 1984;54:163-171.
10. Maehara Y, Emi Y, Moriguchi S, et al. Postoperative chemotherapy for patients with advanced gastric cancer. Am J Surg. 1992;163:577-580.
11. Takenaka K, Yoshida K, Nishizaki T, et al. Postoperative prophylactic lipiodolization reduces the intrahepatic recurrence of hepatocellular carcinoma. Am J Surg. 1995;169:400-405.
12. Hermanek P, Sobin LH. TNM Classification of Malignant Tumors. 4th ed. Geneva, Switzerland: Union Internationale Contre le Cancer (UICC); 1987:43-46.
13. Borrmann R. Geschwulste des Magens und Duodenums. In: Henke F, Lubarsch O, eds. Handbuch der speziellen pathologischen Anatomie und Histologie. Berlin, Germany: Springer-Verlag; 1926;4:865-1054.
14. Mori M, Adachi Y, Wakamura K, et al. Advanced gastric carcinoma simulating early gastric carcinoma. Cancer. 1990;65:1033-1040.
15. Hirai H. A collaborative clinical study of carcinoembryonic antigen in Japan. Cancer Res. 1977;37:2267-2274.
16. Miyauchi A, Onisni T, Morimoto S, et al. Relation of doubling time of plasma calcitonin levels to prognosis and recurrence of medullary thyroid carcinoma. Ann Surg. 1984;194:461-466.
17. Hedley DW, Friedlander ML, Taylor IW, et al. Method for analysis of cellular DNA content of paraffin-embedded pathological material using flow cytometry. J Histochem Cytochem. 1983;31:1333-1335.
18. Vindelov LL, Christensen U, Nissen NI. A detergent-trypsm method for the preparation of nuclei for flow cytometric DNA analysis. Cytometry. 1983;3:323-327.
19. Bloss RS, Miller TA, Copeland EM. Carcinoma of the stomach in the young adult. Surg Gynecol Obstet. 1980;150:883-886.
20. Maehara Y, Orita H, Moriguchi Y, et al. Lower survival rate for patients under 30 years of age and surgically treated for gastric carcinoma. Br J Cancer. 1991;63:1015-1017.
21. Tso PL, Bringaze WL, Dauterive AH, et al. Gastric carcinoma in the young. Cancer. 1987;59:1362-1365.
22. Umehara Y, Kimura T, Yoshida M, et al. Comparison of doubling times of serum carcinoembryonic antigen produced by various metastatic lesions in recurrent gastric and colorectal carcinomas. Cancer. 1993;71:4055-4059.
23. Esaki Y, Hirayama R, Hirokawa K. A comparison of patterns of metastasis in gastric cancer by histologic type and age. Cancer. 1990;65:2086-2090.
24. Maehara, Y, Moriguchi S, Kakeji Y, et al. Pertinent risk factors and gastric carcinoma with synchronous peritoneal dissemination or liver metastasis. Surgery. 1991;110:820-823.
25. Santeusanio G, Peronace L, Gastagna G, et al. Immunohistochemical study of carcinoembryonic antigen (CEA) in gastric tumors: correlation with preoperative serum levels, histologic type, and grade of anaplasia of the tumor. J Surg Oncol. 1988;37:13-19.
26. Denk H, Tappeiner G, Eckerstorfer R, et al. Carcinoembryonic antigen (CEA) in gastrointestinal and extragastrointestinal tumors and its relationship to tumor-cell differentiation. Int J Cancer. 1972;10:262-272.
27. Mai M, Takahashi Y. Prediction of recurrence of gastrointestinal cancer from standpoint of biological malignancies: tumor marker doubling time and its half-life period line. Hum Cell. 1993;6:82-87.
28. Wittekind C, Wachner R, Henke W, et al. Localization of CEA, HCG, lysozyme, alpha-1-antitrypsin and alpha-1-antichymotrypsin in gastric cancer and prognosis. Virchows Arch Pathol Anat. 1986;409:715-724.