Short-term effects of continuous subcutaneous insulin infusion treatment on insulin secretion in non-insulin-dependent overweight patients with poor glycaemic control despite maximal oral anti-diabetic treatment

Diabetes and Metabolism

Volumn 23, Issue 1, 1997, Pages 51-57

  Valensi, P ^a   Moura, I ^b   Le Magoarou, M ^b   Paries J ^b   Perret, G ^b   Attali, J R ^b  

^a HÔPITAL JEAN VERDIER   (France)

^b NONE

Author keywords

continuous subcutaneous insulin infusion; glucagon test; insulin secretion; insulin therapy; insulin requiring diabetes; non insulin dependent diabetes mellitus

Indexed keywords

C PEPTIDE; GLIBENCLAMIDE; GLUCAGON; INSULIN; METFORMIN; ORAL ANTIDIABETIC AGENT;

ADULT; AGED; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HUMAN; HYPERGLYCEMIA; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; ORAL DRUG ADMINISTRATION; SUBCUTANEOUS DRUG ADMINISTRATION;

ADMINISTRATION, CUTANEOUS; ADMINISTRATION, ORAL; ADULT; AGED; AGED, 80 AND OVER; BLOOD GLUCOSE; BODY WEIGHT; C-PEPTIDE; DIABETES MELLITUS; DIABETES MELLITUS, TYPE 2; FEMALE; HUMANS; INFUSIONS, PARENTERAL; INSULIN; MALE; MIDDLE AGED; OBESITY; SECRETORY RATE; TIME FACTORS;

EID: 0031053702     PISSN: 03381684     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Halimi S, Bachelot I, Assal JP, Jeanrenaud B. Acquisitions physiopathologiques récentes et perspectives thérapeutiques dans les diabètes de type II. « Journées de Diabétologie Hôtel-Dieu », Flammarion (Paris), 1987, 117-134.
2. Unger RH, Grundy S. Hyperglycemia as an inducer as well as a consequence of impaired islet cell function and insulin resistance. Diabetologia, 1985, 28, 119-121.
3. Augustin Pascalis I, Richard JL, Rodier M, Orsetti A, Mirouze J. Echec secondaire des antidiabétiques oraux. Intérêt des infusions insuliniques intraveineuses. Diabète Metab, 1986, 12, 1-5.
4. Leblanc H, Marre M, Billault B, Passa Ph. Intérêt de l'association infusion sous-cutanée d'insuline et metformine chez 10 diabétiques insulinonécessitants obèses. Diabète Metab, 1987, 13, 613-617.
5. Hidaka H, Nagulesparan M, Klimes I, et al. Improvement of insulin secretion but not insulin resistance after short-term control of plasma glucose in obese type II diabetics. J Clin Endocrinol Metab, 1982, 54, 217-222.
6. Andrews WJ, Vasquez B, Nagulesparan M, et al. Insulin therapy in obese, non-insulin- dependent diabetes induces improvements in insulin action and secretion that are maintained for two weeks after insulin withdrawal. Diabetes, 1984, 33, 634-642.
7. Leutenegger M, Gross A, Ostermann G, Gruiet H, Pasqual C, Dijoux B. Le diabète insulino- requérant. Diabète Metab, 1988, 14, 463-470.
8. Kerlo-Gillard V, Decaudaveine B, Fontaine P, et al. Insulinothérapie optimisée de 7 jours chez les DIN. Effets sur la glycémie et l'insulinosécrétion. Diabete Metab (Absstract), 1987,XVIII.
9. Leutenegger M, Grulet H, Gross A, Pasqual C. Evolution après séquence de normoglycémie sous pompe du diabète insulinorequérant : au sujet de 60 patients. Diabete Metab (Abstract), 1988, 14, X.
10. Gjessing HJ, Matzen LE, Faber OK, Froland A. Fasting plasma C peptide, glucagon stimulated plasma C peptide, and urinary C peptide in relation to clinical type of diabetes. Diabetologia, 1989, 32, 305-311.
11. Glaser B, Leibovich G, Nesher R, Hartling S, Binder C, Cerasi E. Improved beta-cell function after intensive insulin treatment in severe non-insulin-dependent diabetes. Acta Endocrinol, 1988, 118, 365-373.
12. Scarlett JA, Gray RS, Griffin J, Olefsky JM, Kolterman OG. Insulin treatment reverses the insulin resistance of type II diabetes mellitus. Diabetes Care, 1982, 5, 353-363.
13. Ginsberg H, Rayfield EJ. Effect of insulin therapy on insulin resistance in type II diabetic subjects. Diabetes, 1981, 30, 739-745.
14. Foley JE, Kashiwagi A, Verso MA, Reaven G, Andrews J. Improvement in in vitro insulin action after one month of insulin therapy in obese non-insulin-dependent diabetics. J Clin Invest, 1983, 72, 1901-1909.
15. Nankervis A, Proietto J, Aitken P, Harevood M, Alford F. Differential effects of insulin therapy on hepatic and peripheral insulin sensitivity in type II (non-insulin-dependent) diabetes. Diabetologia, 1985, 28, 427-431.
16. Schemltz R, Hermann J, Wendorf, Filld BJ. Effect of control of blood glucose on plasma insulin responses to various stimuli in secondary failures to oral hypoglycemic agents and in newly diagnosed, maturity onset, ketosis-resistant diabetics. J Clin Endocrinol Metab, 1978, 46, 519.
17. Garvey TW, Olefsky JM, Griffin J, Hammar RF, Kolterman OG. The effect of insulin treatment on insulin secretion and insulin action in type II diabetes mellitus. Diabetes, 1985, 34, 222-234.
18. United Kingdom Prospective Diabetes Study Group. UKPDS 13 : relative efficacy of randomly allocated diet, sulphonylurea, insulin, or metformin in patients with nearly diagnosed non-insulin-dependent diabetes followed for three years. Br Med J, 1995, 310, 83-88.
19. Scarlett JA, Kolterman OG, Giaraldi TP, Kao M. Olefsky JM. Insulin treatment reverses the post-receptor defects in adipocyte 3-O methylglucose transport in type II diabetes mellitus. J Clin Endocrinol Metab, 1983, 56, 1195-1201.
20. Rossetti L, Shulman GI, Zawalich W, De Fronzo RA. Effect of chronic hyperglycemia on in vivo insulin secretion in partially pancreatectomized rate. J Clin Invest, 1987, 80, 1037-1044.
21. Rhodes CJ, Alarcon C. What beta-cell defect could lead to hyperproinsulinemia in NIDDM ? Some clues from recent advances made in understanding the proinsulin-processing mechanism. Diabetes, 1994, 43, 511-517.
22. Temple RC, Carrington CA, Luzio SD, et al. Insulin deficiency in non-insulin-dependent diabetes. Lancet 1989, 1, 293-295.
23. Gin H, Messerchmitt C, Brottier E, Aubertin J. Metformin improves insulin resistance in type 1, insulin-dependent diabetic patients. Metabolism, 1985, 34, 923-925.
24. Augustin-Pascalis I, Richard JL, Parer-Richard C, et al. Réinduction de l'efficacité des ADO dans le DNID après échec secondaire des ADO. Etude des variations de l'insulino-sensibilité. Diabète Métab, 1987, 12, 491.
25. Gormley MJJ, Hadden DR, Woods R. One month's insulin treatment of type II diabetes : the early and medium-term effects following insulin withdrawal. Metabolism, 1986, 35, 1029-1036.