The expression of endothelial tissue plasminogen activator in vivo: A function defined by vessel size and anatomic location

Journal of Cell Science

Volumn 110, Issue 2, 1997, Pages 139-148

  Levin, Eugene G ^a   Santell, Lydia ^a   Osborn, Kent G ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

Endothelial cell; Hyperoxia; Inflammation; Mouse lung; Tissue plasminogen activator

Indexed keywords

TISSUE PLASMINOGEN ACTIVATOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRONCHIAL ARTERY; ENDOTHELIUM CELL; HYPEROXIA; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LUNG; LUNG CIRCULATION; LUNG INJURY; MOUSE; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL;

ANIMALS; ANTIGENS; ENDOTHELIUM; LUNG; MICE; MICE, INBRED C57BL; OXYGEN; PLASMINOGEN ACTIVATORS; PRIMATES; RABBITS; RATS; RNA, MESSENGER;

ANIMALIA; PRIMATES;

EID: 0031053565     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (34)

1. Albelda, S. M., Muller, W. A., Buck, C. A. and Newman, P. J. (1991). Molecular and cellular properties of PECAM-1 (endoCAM/CD31): A novel vascular cell-cell adhesion molecule. J. Cell Biol. 114, 1059-1068.
2. Augustin, H. G., Kozian, D. H. and Johnson, R. C. (1994). Differentiation of endothelial cells: Analysis of the constitutive and activated endothelial cell phenotypes. BioEssays 16, 901-906.
3. Balentine, J. D. (1982). Principles of hyperoxic pathophysiology. In Pathology of Oxygen Toxicity, vol. 1 (ed. J. D. Balentine). pp. 31-81. Academic Press, New York.
4. Beckstead, J. H. (1994). A simple technique for preservation of fixation-sensitive antigens in paraffin-embedded tissues. J. Histochem. Cytochem. 42, 1127-1134.
5. Bienvenu, K., Hernandez, L. and Granger, D. N. (1992). Leukocyte adhesion and emigration in inflammation. Ann. NY Acad. Sci. 664, 388-399.
6. Carmeliet, P., Schoonjans, L., Stassen, J. M., Van Nuffelen, A., De Mol, M., Collen, D. and Mulligan, R. (1993). Gene inactivation of tissue-type plasminogen activator, urokinase-type plasminogen activator and plasminogen activator inhibitor-1 in mice. Thromb. Haemost. 69, 799 (abstract).
7. Carmeliet, P., Schoonjans, L., Kieckens, L., Ream, B., Degen, J., Bronson, R., De Vos, R., Van den Oord, J. J., Collen, D. and Mulligan, R. C. (1994). Physiological consequences of loss of plasminogen activator gene function in mice. Nature 368, 419-424.
8. Collen, D. (1980). On the regulation and control of fibrinolysis. Thromb. Haemost. 43, 77-89.
9. Goerdt, S. and Sorg, C. (1992). Endothelial heterogeneity and the acquired immunodeficiency syndrome: A paradigm for the pathogenesis of vascular disorders. Clin. Invest. 70, 89-98.
10. Granger, D. N. and Korthuis, R. J. (1995). Physiologic mechanisms of postischemic tissue injury (Review). Annu. Rev. Physiol. 57, 311-332.
11. Hanss, M. and Collen, D. (1987). Secretion of tissue-type plasminogen activator and plasminogen activator inhibitor by cultured human endothelial cells: modulation by thrombin, endotoxin, and histamine. J. Lab. Clin. Med. 109, 97-104.
12. Korhonen, J., Lahtinen, I., Halmekyto, M., Alhonen, L., Janne, J., Dumont, D. and Alitalo, K. (1995). Endothelial-specific gene expression directed by the tie gene promoter in vivo. Blood 86, 1828-1835.
13. Kurose, I., Anderson, D. C., Miyasaka, M., Tamatani, T., Paulson, J. C., Todd, R. F., Rusche, J. R. and Granger, D. N. (1994). Molecular determinants of reperfusion-induced leukocyte adhesion and vascular protein leakage. Circ. Res. 74, 336-343.
14. Laemmli, U. K. (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 277, 680-685.
15. Levin, E. G. (1983). Latent tissue plasminogen activator produced by human endothelial cells in culture: Evidence for an enzyme-inhibitor complex. Proc. Nat. Acad. Sci. USA 80, 6804-6808.
16. Levin, E. G., Marzec, U., Anderson, J. and Harker, L. A. (1984). Thrombin stimulates tissue plasminogen activator release from cultured human endothelial cells. J. Clin. Invest. 74, 1988-1995.
17. Levin, E. G. and Santell, L. (1988). Stimulation and desensitization of tissue plasminogen activator release from human endothelial cells. J. Biol. Chem. 263, 9360-9365.
18. Magno, M. (1990). Comparative anatomy of the tracheobronchial circulation. Eur. Resp. J. 12, 557s-562s.
19. Manchanda, N. and Schwartz, B. S. (1990). Lipopolysaccharide-induced modulation of human monocyte urokinase production and activity. J. Immunol. 145, 4174-4180.
20. Nagaishi, C. (1972). Functional Anatomy and Histology of the Lung. University Press, Baltimore.
21. Pandolfi, M. (1975). Histochemistry of tissue plasminogen activator. Thromb. Diath. Haemorrh. 34, 661-663.
22. Preissner, K. T. and Potzsch, B. (1995). Vessel wall-dependent metabolic pathways of the adhesive proteins, von-Willebrand factor and vitronectin. Histol. Histopathol. 10, 239-251.
23. Pries, A. R., Secomb, T. W. and Gaehtgens, P. (1995). Structure and hemodynamics of microvascular networks: heterogeneity and correlations. Am. J. Physiol. Heart Circ. Physiol. 269, H1713-H1722.
24. Robbins, K. C. (1978). The human plasma fibrinolytic system: regulation and control. Mol. Cell. Biol. 20, 149-157.
25. Sambrook, J., Fritsch, E. F. and Maniatis, T. (1989). Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
26. Sappino, A. P., Madani, R., Huarte, J., Belin, D., Kiss, J. Z., Wohlwend, A. and Vassalli, J. D. (1993). Extracellular proteolysis in the adult murine brain. J. Clin. Invest. 92, 679-685.
27. Schlichter, J. and Harris, R. (1949). The vascularization of the aorta. II. A comparative study of the aortic vascularization of several species in health and disease. Am. J. Med. Sci. 218, 610-615.
28. Shatos, M. A., Doherty, J. M., Orfeo, T., Hoak, J. C., Collen, D. and Stump, D. C. (1992). Modulation of the fibrinolytic response of cultured human vascular endothelium by extracellularly generated oxygen radicals. J. Biol. Chem. 267, 597-601.
29. Suzuki, S., Toledo-Pereyra, L. H. and Rodriguez, F. J. (1994). Role of neutrophils during the first 24 hours after liver ischemia and reperfusion injury. Transplant. Proc. 26, 3695-3700.
30. Todd, A. S. (1959). Histological localization of fibrolysin activator. J. Pathol. Bact. 78, 281-283.
31. Tschesche, H., Knauper, V., Kramer, S., Michaelis, J., Oberhoff, R. and Reinke, H. (1992). Latent collagenase and gelatinase from human neutrophils and their activation. Matrix Suppl. 1, 245-255.
32. van Hinsbergh, V. W., Kooistra, T., Emeis, J. J. and Koolwijk, P. (1991). Regulation of plasminogen activator production by endothelial cells: Role in fibrinolysis and local proteolysis. Int. J. Radiat. Biol. 60, 261-272.
33. van Zonneveld, A.-J., Chang, G. T. G., van den Berg, J., Kooistra, T., Verheijen, J. H., Pannekoek, H. and Kluft, C. (1986). Quantification of tissue-type plasminogen activator (t-PA) mRNA in human endothelial-cell cultures by hybridization with a t-PA cDNA probe. Biochem. J. 235, 385-390.
34. Woerner, C. A. (1951). Vasa vasorum of arteries, their demonstration and distribution. In The Arterial Wall (ed. A. I. Lansing), pp. 1-15. Williams & Wilkins, Baltimore.