Analysis of the allele-specific PCR method for the detection of neoplastic disease

Diagnostic Molecular Pathology

Volumn 6, Issue 1, 1997, Pages 49-57

  Rhodes, C Harker ^a   Honsinger, Charles ^a   Porter, Donna M ^a   Sorenson, George D ^a  

^a DARTMOUTH HITCHCOCK MEDICAL CENTER   (United States)

Author keywords

Allele specific PCR; Peptide nucleic acid

Indexed keywords

ALLELE; ARTICLE; DNA SEQUENCE; GENE LOCUS; GENE MUTATION; GENETIC ANALYSIS; HUMAN; HUMAN CELL; NEOPLASM; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; TUMOR DIAGNOSIS;

ALLELES; DNA PRIMERS; DNA-DIRECTED DNA POLYMERASE; GENES, P53; GENES, RAS; HUMANS; MUTATION; NEOPLASMS; PEPTIDE FRAGMENTS; POLYMERASE CHAIN REACTION; TAQ POLYMERASE; TEMPLATES, GENETIC;

EID: 0031053540     PISSN: 10529551     EISSN: None     Source Type: Journal    
DOI: 10.1097/00019606-199702000-00008     Document Type: Article

References (32)

1. Berthélemy P, Bouisson M, Escourrou J, Vaysse N, Rumeau JL, Pradayrol L. Identification of K-ras mutations in pancreatic juice in the early diagnosis of pancreatic cancer. Ann Intern Med 1995; 123:188-91.
2. Bos JL. Ras oncogenes in human cancer: a review. Cancer Res 1989;49:4682-9.
3. Brennan JA, Mao L, Hruban RH, et al. Molecular assessment of histopathological staging in squamous-cell carcinoma of the head and neck. N Engl J Med 1995;332(7):429-35.
4. Cha RS, Zarbl H, Keohavong P, Thilly WG. Mismatch amplification mutation assay (MAMA): application to the c-H-ras gene. PCR Methods Appl 1992;2:14-20.
5. Ehlen T, Dubeau L. Detection of ras point mutations by polymerase chain reaction using mutation-specific, inosine-containing oligonucleotide primers. Biochem Biophys Res Comm 1989;160: 441-7.
6. Haliassos A, Chomel JC, Grandjouan S, Kruh J, Kaplan JC, Kitzis A. Detection of minority point mutations by modified PCR technique: a new approach for a sensitive diagnosis of tumor-progression markers. Nucleic Acids Res 1989;17:8093-9.
7. Hayashi N, Arakawa H, Nagase H, et al. Genetic diagnosis identifies occult lymph node metastases undetectable by the histopathological method. Cancer Research 1994;54:3853-6.
8. Hayashi N, Ito I, Yanagisawa A, et al. Genetic diagnosis of lymphnode metastasis in colorectal cancer. Lancet 1995;345:1257-9.
9. Huang MM, Arnheim N, Goodman MF. Extension of base mispairs by Taq DNA polymerase: implications for single nucleotide discrimination in PCR. Nucleic Acids Res 1992;20:4567-73.
10. Inoue S, Nakao A, Kasai Y, Harada A, Nonami T, Takagi H. Detection of hepatic micrometastasis in pancreatic adenocarcinoma patients by two-stage polymerase chain reaction/restriction fragment length polymorphism analysis. Jpn J Cancer Res 1995; 86:626-30.
11. Kwok S, Kellogg DE, McKinney N, et al. Effects of primer-template mismatches on the polymerase chain reaction: human immunodeficiency virus type 1 model studies. Nucleic Acids Res 1990;18:999-1005.
12. Loda M. Polymerase chain reaction-based methods for the detection of mutations in oncogenes and tumor suppressor genes. Hum Pathol 1994;25:564-71.
13. Mao L, Hruban RH, Boyle JO, Tockman M, Sidransky D. Detection of oncogene mutations in sputum precedes diagnosis of lung cancer. Cancer Res 1994;54:1634-7.
14. Mendelman LV, Petruska J, Goodman MF. Base mispair extension kinetics. Comparison of DNA polymerase alpha and reverse transcriptase. J Biol Chem 1990;265:2338-46.
15. Mills NE, Fishman CL, Scholes J, Anderson SE, Rom WN, Jacobson DR. Detection of K-ras oncogene mutations in bronchoalveolar lavage fluid for lung cancer diagnosis. J Natl Cancer Inst 1995;87:1056-60.
16. Newton CR, Graham A, Heptinstall LE, et al. Analysis of any point mutation in DNA. The amplification refractory mutation system (ARMS). Nucleic Acids Res 1989;17:2503-16.
17. Nielsen PE, Egholm M, Berg RH, Buchardt O. Sequence-selective recognition of DNA by strand displacement with a thymine-substituted polyamide. Science 1991;254:1497-500.
18. Ørum H, Nielsen PE, Egholm M, Berg RH, Buchardt O, Stanley C. Single base pair mutation analysis by PNA directed PCR clamping. Nucleic Acids Res 1993;21:5332-6.
19. Perrino FW, Loeb LA. Differential extension of 3′ mispairs is a major contribution to the high fidelity of calf thymus DNA polymerase-alpha. J Biol Chem 1989;264:2898-905.
20. Petruska J, Goodman MF, Boosalis MS, Sowers LC, Cheong C, Tinoco I. Comparison between DNA melting thermodynamics and DNA polymerase fidelity. Proc Natl Acad Sci USA 1988;85: 6252-6.
21. Rhodes CH, Honsinger C, Sorenson GD. Detection of tumor-derived DNA in cerebrospinal fluid. J Neuropathol Exp Neurol 1994;53:364-8.
22. Rhodes CH, Honsinger C, Sorenson GD. PCR-detection of tumor-derived p53 DNA in cerebrospinal fluid. Am J Clin Pathol 1995; 103:404-8.
23. Sarkar G, Cassady J, Bottema CD, Sommer SS. Characterization of polymerase chain reaction amplification of specific alleles. Analyt Biochem 1990;186:64-8.
24. Sidransky D, Tokino T, Hamilton SR, et al. Identification of ras oncogene mutations in the stool of patients with curable colorectal tumors. Science 1992;256:102-4.
25. Sidransky D, Von EA, Tsai YC, et al. Identification of p53 gene mutations in bladder cancers and urine samples. Science 1991;252: 706-9.
26. Sommer SS, Groszbach AR, Bottema CD. PCR amplification of specific alleles (PASA) is a general method for rapidly detecting known single-base changes. Biotechniques 1992;12:82-7.
27. Sorenson GD, Pribish DM, Valone FH, Memoli VA, Bzik DJ, Yao SL. Soluble normal and mutated DNA sequences from single-copy genes in human blood. Cancer Epidemiol Biomarkers Prev 1994; 3:67-71.
28. Stork P, Loda M, Bosari S, Wiley B, Poppenhusen K, Wolfe H. Detection of K-ras mutations in pancreatic and hepatic neoplasms by non-isotopic mismatched polymerase chain reaction. Oncogene 1991;6:857-62.
29. Tada M, Omata M, Kawai S, et al. Detection of ras gene mutations in pancreatic juice and peripheral blood of patients with pancreatic adenocarcinoma. Cancer Res 1993;53:2472-4.
30. Tobi M, Luo FC, Ronai Z. Detection of K-ras mutation in colonic effluent samples from patients without evidence of colorectal carcinoma. J Nat Cancer Inst 1994;86:1007-10.
31. Ugozzoli L, Wallace RB. Allele-specific polymerase chain reaction. Methods Enzymol 1991;2:42-8.
32. Wu DY, Ugozzoli L, Pal BK, Wallace RB. Allele-specific enzymatic amplification of beta-globin genomic DNA for diagnosis of sickle cell anemia. Proc Natl Acad Sci USA 1989;86:2757-60.