Nerve-induced release of nitric oxide in the rabbit gastrointestinal tract as measured by in vivo microdialysis

British Journal of Pharmacology

Volumn 120, Issue 4, 1997, Pages 702-706

  Iversen, Henrik H ^a   Celsing, Fredrik ^b   Leone, Anna M ^c   Gustafsson, Lars E ^a   Wiklund, N Peter ^b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c WELLCOME RESEARCH LABORATORIES   (United Kingdom)

Author keywords

Capillary electrophoresis; Gastrointestinal tract; Microdialysis; Nitrate; Nitric oxide; Nitrite; Vagal nerve

Indexed keywords

ARGININE METHYL ESTER; NEUROTRANSMITTER; NITRATE; NITRIC OXIDE; NITRITE;

ANIMAL EXPERIMENT; ARTICLE; ASCENDING COLON; CAPILLARY ELECTROPHORESIS; FEMALE; GASTROINTESTINAL TRACT; MALE; MICRODIALYSIS; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; STOMACH; VAGUS NERVE STIMULATION;

ANIMALS; COLON; ELECTRIC STIMULATION; FEMALE; MALE; MICRODIALYSIS; MUSCLE CONTRACTION; MUSCLE, SMOOTH; NITRATES; NITRIC OXIDE; NITRITES; RABBITS; STOMACH; VAGUS NERVE;

EID: 0031053527     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0700967     Document Type: Article

References (36)

1. AMBERG, G. & LINDEFORS, N. (1989). Intracerebral microdialysis: II. Mathematical studies of diffusion kinetics. J. Pharmacol. Methods, 22, 157-183.
2. ÄNGGÅRD, E. (1994). Nitric oxide: mediator, murderer, and medicine. Lancet, 343, 1199-1206.
3. BENVENISTE, H., HANSEN, A.J. & OTTOSEN, N.S. (1989). Determination of brain interstitial concentrations by microdialysis. J. Neurochem., 52, 1741-1750.
4. BOECKXSTAENS, G.E., PELCKMANS, P.A., BULT, H., DE MAN, J.G., HERMAN, A.G. & VAN MAERCKE, Y.M. (1990). Non-adrenergic non-cholinergic relaxation mediated by nitric oxide in the canine ileocolonic junction. Eur. J. Pharmacol., 190, 239-246.
5. BOUGHTON-SMITH, N.K., EVANS, S.M., HAWKEY, C.J., COLE, A.T., BALSITIS, M., WHITTLE, B.J.R. & MONCADA, S. (1993). Nitric oxide synthase activity in ulcerative colitis and Crohn's disease. Lancet, 342, 338-340.
6. BREDT, D.S., HWANG, P.H. & SNYDER, S.H. (1991). Localization of nitric oxide synthase indicating a role for nitric oxide. Nature, 351, 714-718.
7. BULT, H., BOECKXSTAENS, G.E., PELCKMANS, P.A., JORDAENS, F.H., VAN MAERCKE, Y.M. & HERMAN, A.G. (1990). Nitric oxide as an inhibitory non-adrenergic non-cholinergic neurotransmitter. Nature, 345, 346-347.
8. CALIGNANO, A., WHITTLE, B.J.R., DI ROSA, M & MONCADA, S. (1992). Involvement of endogenous nitric oxide in the regulation of rat intestinal motility in vivo. Eur. J. Pharmacol., 229, 273-276.
9. COSTA, M., FURNESS, J.B., POMPOLO, S., BROOKS, S.J.H., BORNSTEIN, J.C., BREDT, D.S. & SNYDER, S.H. (1992). Projections and chemical coding of neurons with immunoreactivity for nitric oxide synthase in the guinea-pig small intestine. Neurosci. Lett., 148, 121-125.
10. DESAI, K.M., SESSA, W.C. & VANE, J.R. (1991). Involvement of nitric oxide in the reflex relaxation of the stomach to accomodate food or fluid. Nature, 351, 477-479.
11. GUSTAFSSON, L.E., WIKLUND, C.U., WIKLUND, N.P., PERSSON, M. & MONCADA, S. (1990). Modulation of neuroeffector transmission by nitric oxide in guinea pig ileum. Biochem. Biophys. Res. Commun., 173, 106-110.
12. HATA, F., ISHII, T., KANADA, A., YAMANO, N., KATAOKA, T., TAKEUCHI, T. & YAGASAKI, O. (1990). Essential role for nitric oxide in descending inhibition in the rat proximal colon. Biochem. Biophys. Res. Commun., 172, 1400-1406.
13. IGNARRO, L.J., FUKUTO, J.M., GRISCAVAGE, J.M., ROGERS, N.E.& BYRNS, R.E. (1993). Oxidation of nitric oxide in aqueous solution to nitrite but not nitrate: Comparison with enzymatically formed nitric oxide from L-arginine. Proc. Natl. Acad. Sci. U.S.A., 90, 8103-8107.
14. IVERSEN, H.H., GUSTAFSSON, L.E., LEONE, A.M. & WIKLUND, N.P. (1994a). Smooth muscle relaxing effects of NO, nitrosothiols and a nerve-induced relaxing factor released in guinea-pig colon. Br. J. Pharmacol., 113, 1088-1092.
15. IVERSEN, H.H., WIKLUND, N.P. & GUSTAFSSON, L.E. (1994b). Nitric oxide-like activity in guinea pig colon as determined by effector responses, bioassay and chemiluminescence analysis. Acta Physiol. Scand., 152, 315-322.
16. JACOBSON, I., SANDBERG, M. & HAMBERGER, A. (1985). Mass transfer in brain dialysis devices - a new method for estimation of extracellular amino acids concentration. J. Neurosci. Methods, 15, 263-268.
17. LEAF, F.D., WISHNOK, J.S. & TANNENBAUM, S.R. (1990). Nitric oxide: the dark side. In Nitric Oxide from L-Arginine: a Bioregulatory System, ed. Moncada, S. & Higgs, E.A. pp. 291-299. Amsterdam: Elsevier.
18. LEONE, A.M., FRANCIS, P.L., RHODES, P. & MONCADA, S. (1994a). A rapid and simple method for the measurement of nitrite and nitrate in plasma by high performance capillary electrophoresis. Biochem. Biophys. Res. Commun., 200, 951-957.
19. LEONE, A.M., WIKLUND, N.P., HÖKFELT, T., BRUNDIN, L. & MONCADA, S. (1994b). Release of nitric oxide by nerve stimulation in the urogenital tract. NeuroReport, 5, 733-736.
20. LUO, D., KNEZEVICH, S. & VINCENT, S.R. (1993). N-methyl-D-aspartate-induced nitric oxide release: An in vivo microdialysis study. Neuroscience, 57, 897-900.
21. LÖNNROTH, P., JANSSON, P.-A. & SMITH, U. (1987). A microdialysis method allowing characterization of intercellular water space in humans. Am. J. Physiol., 253, E228-E231.
22. MARTINSSON, J. (1965). The effect of graded vagal stimulation on gastric motility, secretion and blood flow in the cat. Acta Physiol. Scand., 65, 300-309.
23. MEARIN, F., MOURELLE, M., GUARNER, F., SALAS, A., RIVEROS-MORENO, V. MONCADA, S. & MALAGELADA, J.-R. (1993). Patients with achalasia lack nitric oxide synthase in the gastrooesophageal junction. Eur. J. Clin. Invest., 23, 724-728.
24. MEIRIEN, O., PAIRET, M., SUTRA, J.F. & RUCKEBUSCH, M. (1986). Local release of monoamines in the gastrointestinal tract: An in vivo study in rabbits. Life Sci., 38, 827-834.
25. MONCADA, S., PALMER, R.M.J. & HIGGS, E.A. (1991). Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol. Rev., 43, 109-142.
26. OHTA, K., ARAKI, N., SHIBATA, M., HAMADA, J., KOMATSUMOTO, S., SHIMAZU, K. & FUKUUCHI, Y. (1994). A novel in vivo assay system for consecutive measurement of brain nitric oxide production combined with the microdialysis technique. Neurosci. Lett., 176, 165-168.
27. PALMER, R.M.J., FERRIGE, A.G. & MONCADA, S. (1987). Nitric oxide release accounts for the biological activity of the endothelium-derived relaxing factor. Nature, 327, 524-526.
28. SANDERS, K.M. & WARD, S.M. (1992). Nitric oxide as a mediator of nonadrenergic noncholinergic neurotransmission. Am. J. Physiol., 262, G379-G392.
29. SHUTTLEWORTH, C.W.R., MURPHY, R. & FURNESS, J.B. (1991). Evidence that nitric oxide participates in non-adrenergic inhibitory transmission to intestinal muscle in guinea-pig. Neurosci. Lett., 130, 77-80.
30. STÅHLE, L., SEGERSVÄRD, S. & UNGERSTEDT, U. (1991). A comparison between three methods for estimation of extracellular concentrations of exogenous and endogenous compounds by microdialysis. J. Pharmacol. Methods, 25, 41-52.
31. TOSSMAN, U. & UNGERSTEDT, U. (1986). Microdialysis in the study of extracellular levels of amino acids in the rat brain. Acta Physiol. Scand., 128, 9-14.
32. UNGERSTEDT, U. (1991). Microdialysis-principles and applications for studies in animals and man. J. Intern. Med., 230, 365-373.
33. VANDERWINDEN, J.-M., DE LAET, M.-H., SCHIFFMANN, S.N., MAILLEUX, P., LOWENSTEIN, C.J., SNYDER, S.H. & VANDERHAEGHEN, J.-J. (1993). Nitric oxide synthase distribution in the enteric nervous system of Hirschprung's disease. Gastroenterology, 105, 969-973.
34. VANDERWINDEN, J.-M., MAILLEUX, P., SCHIFFMANN, S.N., VANDERHAEGHEN, J.-J. & DE LACT, M.H. (1992). Nitric oxide synthase activity in infantile hypertrophic pyloric stenosis. N. Engl. J. Med., 327, 511-515.
35. WENNMALM, Å. (1995). Metabolism and excretion of nitric oxide in man: basal studies and applications. Agents & Actions (Suppl.), 45, 129-138.
36. WIKLUND, N.P., LEONE, A.M., GUSTAFSSON, L.E. & MONCADA, S. (1993). Release of nitric oxide evoked by nerve stimulation in guinea-pig intestine. Neurosci., 53, 607-611.