Simplified Sizing of Low-Density Lipoprotein Using Polyacrylamide Gradient Gel Electrophoresis of Plasma

Clinical Chemistry and Laboratory Medicine

Volumn 35, Issue 1, 1997, Pages 17-20

  Westhuyzen, Justin ^a   Graham, Scott D ^a   Rasiah, Rohan L ^a   Saltissi, David ^a  

^a ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANAZOLENE SODIUM; LOW DENSITY LIPOPROTEIN;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FRACTIONATION; HUMAN; IMAGE ANALYSIS; LIPOPROTEIN BLOOD LEVEL; MOLECULAR SIZE; PARTICLE SIZE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; ULTRACENTRIFUGATION;

ADULT; AGED; ARTERIOSCLEROSIS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; KIDNEY FAILURE, CHRONIC; LIPOPROTEINS, LDL; MALE; MOLECULAR WEIGHT; ROSANILINE DYES; SOFTWARE;

EID: 0031053073     PISSN: 14346621     EISSN: 14374331     Source Type: Journal    
DOI: 10.1515/cclm.1997.35.1.17     Document Type: Article

References (13)

1. Austin MA, Breslow JL, Hennekens CH, Buring JE, Willett WC, Krauss RM. Low-density lipoprotein subclass patterns and risk of myocardial infarction. J Am Med Assoc 1988; 26: 1917-1921.
2. Austin MA, King MC, Vranizan KM, Krauss RM. Atherogenic lipoprotein phenotype: a proposed genetic marker for coronary heart disease risk. Circulation 1990; 82: 495-506.
3. Coresh J, Kwiterovich PO, Smith HH, Bachorik PS. Association of plasma triglyceride concentration and LDL particle diameter, density and chemical composition with premature coronary artery disease in men and women. J Lipid Res 1993; 34: 1687-1697.
4. Griffin BA, Freeman DJ, Tait GW, Thomson J, Caslake MJ, Packard CJ, et al. Role of plasma triglyceride in the regulation of low density lipoprotein (LDL) subfractions: relative contribution of small, dense LDL to coronary heart disease risk. Atherosclerosis 1994; 106: 241-253.
5. Rajman I, Maxwell S, Cramb R, Kendall M. Particle size: the key to the atherogenic lipoprotein? Q J Med 1994; 87: 709-720.
6. O'neal D, Lee P, Murphy B, Best J. Low-density lipoprotein particle size distribution in end-stage renal disease treated with hemodialysis or peritoneal dialysis. Am J Kidney Dis 1996; 27: 84-91.
7. Shen MS, Krauss RM, Lindgren FT, Forte TM. Heterogeneity of serum low density lipoproteins in normal human subjects. J Lipid Res 1981; 22: 236-244.
8. Krauss RM, Burke DJ. Identification of multiple subclasses of plasma low density lipoproteins in normal humans. J Lipid Res 1982; 23: 97-104.
9. Nichols AV, Krauss RM, Musliner TA. Nondenaturing polyacrylamide gradient gel electrophoresis. Methods in Enymology 1986; 128: 417-431.
10. Sattler W, Bone P, Stocker R. Isolation of human VLDL, LDL, HDL and two subclasses in the TL-100 tabletop centrifuge using the TLA-100.4 rotor. Beckman Technical Information, 1992.
11. McNamara JR, Campos H, Ordovas JM, Peterson J, Wilson PWF, Schaefer EJ. Effect of gender, age, and lipid status on low density lipoprotein subfraction distribution. Results from the Framingham offspring study. Arteriosclerosis 1987; 7: 483-490.
12. Princen HMG, van Duyvenvoorde W, Buytenhek R, van der Laarse A, von Poppel G, Leuven JAG, et al. Supplementation with low doses of vitamin E protects LDL from lipid peroxidation in men and women. Arterioscler Thromb Vase Biol 1995; 15: 325-333.
13. McNamara JR, Campos H, Adolphson JL, Ordovas JM, Wilson WF, Albers JJ, et al. Screening for lipoprotein[a] elevations in plasma and assessment of size heterogeneity using gradient gel electrophoresis. J Lipid Res 1989; 30: 747-755.