Relationship between calculated blood concentration of propofol and electrophysiological variables during emergence from anaesthesia: Comparison of bispectral index, spectral edge frequency, median frequency and auditory evoked potential index

British Journal of Anaesthesia

Volumn 78, Issue 2, 1997, Pages 180-184

  Doi, M ^a   Gajraj, R J ^a   Mantzaridis, H ^b   Kenny, G N C ^c  

^a HCI International Medical Centre   (United Kingdom)

^b Law Hospital   (United Kingdom)

^c GLASGOW ROYAL INFIRMARY   (United Kingdom)

Author keywords

Anaesthesia, depth; Anaesthetics i.v., propofol; Brain, evoked potentials; Monitoring, evoked potentials

Indexed keywords

PROPOFOL;

ADULT; AGED; ARTICLE; BRAIN ELECTROPHYSIOLOGY; CLINICAL ARTICLE; CORRELATION FUNCTION; DRUG BLOOD LEVEL; ELECTROENCEPHALOGRAPHY; EVOKED AUDITORY RESPONSE; FEMALE; HUMAN; INTERMETHOD COMPARISON; INTRAVENOUS DRUG ADMINISTRATION; PRIORITY JOURNAL; SLEEP; WAKEFULNESS;

EID: 0031052593     PISSN: 00070912     EISSN: None     Source Type: Journal    
DOI: 10.1093/bja/78.2.180     Document Type: Article

References (23)

1. Kearse LA jr, Manberg P, Chamoun N, DeBros F, Zaslavsky A. Bispectral analysis of the electroencephalogram correlates with patient movement to skin incision during propofol/nitrous oxide anesthesia. Anesthesiology 1994; 81: 1365-1370.
2. Vernon JM, Lang E, Sebel PS, Manberg P. Prediction of movement using bispectral electroencephalographic analysis during propofol/alfentanil or isoflurane/alfentanil anesthesia. Anesthesia and Analgesia 1995; 80: 780-785.
3. Leslie K, Sessler DI, Schroeder M, Walters K. Propofol blood concentration and the bispectral index predict suppression of learning during propofol/epidural anesthesia in volunteers. Anesthesia and Analgesia 1995; 81: 1269-1274.
4. Schwilden H, Stoeckel H, Schüttler J. Closed-loop feedback control of propofol anaesthesia by quantitative EEG analysis in humans. British Journal of Anaesthesia 1989; 62: 290-296.
5. Traast HS, Kalkman CJ. Electroencephalographic characteristics of emergence from propofol/sufentanil total intravenous anesthesia. Anesthesia and Analgesia 1995; 81: 366-371.
6. Gaitini L, Vaida S, Collins G, Somri M, Sabo E. Awareness detection during caesarean section under general anaesthesia using EEG spectrum analysis. Canadian Journal of Anaesthesia 1995; 42: 377-381.
7. Thornton C, Konieczko KM, Knight AB, Kaul B, Jones JG, Dore CJ, White DC. Effect of propofol on the auditory evoked response and oesophageal contractility. British Journal of Anaesthesia 1989; 63: 411-417.
8. Davies FW, Mantzaridis H, Fisher AC, Kenny GN, Fisher C. Middle latency auditory evoked potentials during repeated transitions from consciousness to unconsciousness. Anaesthesia 1996; 51: 107-113.
9. Newton DE, Thornton C, Konieczko KM, Jordan C, Webster NR, Luff NP, Frith CD, Dore CJ. Auditory evoked response and awareness: a study in volunteers at sub-MAC concentrations of isoflurane. British Journal of Anaesthesia 1992; 69: 122-129.
10. Kenny GN, Davies FW, Mantzaridis H. Transition between consciousness and unconsciousness during anesthesia. Anesthesiology 1993; 79: A330.
11. Kenny GN, McFadzean WA, Mantzaridis H, Fisher AC. Closed-loop control of anesthesia. Anesthesiology 1992; 77: A328.
12. Mantzaridis H. Development of an AEP system. In: Closed Loop Control of Anaesthesia, PhD thesis. Glasgow: Strathclyde University, 1996; in press.
13. Kenny GN, White M. A portable target controlled propofol infusion system. International Journal of Clinical Monitoring and Computing 1992; 9: 179-182.
14. Smith WD. Measuring the performance of depth indicators. Anesthesiology 1996; 84: 38-51.
15. Chassard D, Joubaud A, Colson A, Guiraud M, Dubreuil C, Banssillon V. Auditory evoked potentials during propofol anaesthesia in man. British Journal of Anaesthesia 1989; 62: 522-526.
16. Howell S, Gan TJ, Martel D, Glass PSA. Defining the CP50 and BIS50 for propofol alone and propofol with alfentanil. Anesthesiology 1995; 83: A367.
17. Flaishon R, Sebel PS, Sigl J. Bispectral analysis of the EEG for monitoring the hypnotic effect of propofol and propofol/alfentanil. Anesthesiology 1995; 83: A514.
18. Kearse L, Rosow C, Sebel P, Bloom M, Glass P, Howell S. The bispectral index correlates with sedation/hypnosis and recall: comparison using multiple agents. Anesthesiology 1995; 83: A507.
19. Schwender D, Daunderer M, Mulzer S, Klasing S, Finsterer U, Peter K. Spectral edge frequency of the electroencephalogram to monitor "depth" of anaesthesia with isoflurane or propofol. British Journal of Anaesthesia 1996; 77: 179-184.
20. Marsh BJ, White M, Morton N, Kenny GN. Pharmacokinetic model driven infusion of propofol in children. British Journal of Anaesthesia 1991; 67: 41-48.
21. Davidson JA, Macleod AD, Howie JC, White M, Kenny GN. Effective concentration 50 for propofol with and without 67% nitrous oxide. Acta Anaesthesiologica Scandinavica 1993; 37: 458-464.
22. Thornton C, Konieczko K, Jones JG, Jordan C, Dore CJ, Heneghan CP. Effect of surgical stimulation on the auditory evoked response. British Journal of Anaesthesia 1988; 60: 372-378.
23. Newton DE, Thornton C, Creagh Barry P, Dore CJ. Early cortical auditory evoked response in anaesthesia: comparison of the effects of nitrous oxide and isoflurane. British Journal of Anaesthesia 1989; 62: 61-65.