Effects of log P and phenyl ring conformation on the binding of 5- phenylhydantoins to the voltage-dependent sodium channel

Journal of Medicinal Chemistry

Volumn 40, Issue 4, 1997, Pages 602-607

  Brown, Milton L ^a   Brown, George B ^b   Brouillette, Wayne J ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 PHENYLHYDANTOIN; ANTICONVULSIVE AGENT; HYDANTOIN DERIVATIVE; ION CHANNEL; PHENYTOIN; SODIUM CHANNEL; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ANTICONVULSANT THERAPY; ARTICLE; BRAIN CORTEX; BRAIN SYNAPTOSOME; DRUG BINDING; DRUG SYNTHESIS; MEMBRANE BINDING; MEMBRANE ELECTROPHYSIOLOGY; NERVE CELL EXCITABILITY; NONHUMAN; RAT; SEIZURE;

ANIMALS; BATRACHOTOXINS; CEREBRAL CORTEX; HUMANS; HYDANTOINS; KINETICS; RATS; SODIUM CHANNELS; SYNAPTOSOMES;

EID: 0031052522     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm960692v     Document Type: Article

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