The involvement of phosphatidylinositol 3-kinase in crystal induced human neutrophil activation

Journal of Rheumatology

Volumn 24, Issue 2, 1997, Pages 341-348

  Jackson, John K ^a   Lauener, Ron ^b   Duronio, Vincent ^b   Burt, Helen M ^a,c  

^a Faculty of Pharmaceutical Sciences   (Canada)

^b JACK BELL RESEARCH CENTRE   (Canada)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

calcium pyrophosphate dihydrate; monosodium urate monohydrate; neutrophils; phosphatidylinositol 3 kinase

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CALCIUM PYROPHOSPHATE; PHOSPHATIDYLINOSITOL 3 KINASE; WORTMANNIN;

ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; CRYSTAL; HUMAN; HUMAN CELL; INFLAMMATION; NEUTROPHIL; PRIORITY JOURNAL;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANDROSTADIENES; CALCIUM PYROPHOSPHATE; CELLS, CULTURED; CHEMILUMINESCENT MEASUREMENTS; CHROMONES; CRYSTALLIZATION; CYTOPLASMIC GRANULES; ENZYME INHIBITORS; HUMANS; MORPHOLINES; NEUTROPHIL ACTIVATION; NEUTROPHILS; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); RESPIRATORY BURST; SIGNAL TRANSDUCTION; SUPEROXIDES; URIC ACID;

EID: 0031052461     PISSN: 0315162X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. McCarty DJ: Pathogenesis and treatment of crystal-induced inflammation. In: McCarty DJ, ed. Arthritis and Allied Conditions. Philadelphia: Lea and Febiger, 1985:1495-514.
2. Onello E, Traynor-Kaplan A, Sklar L, Terkeltaub R: Mechanism of neutrophil activation by an unopsonized inflammatory particulate. J Immunol 1991;146:4289-94.
3. Terkeltaub R, Sklar LA, Mueller H: Neutrophil activation by inflammatory microcrystals of monosodium urate monohydrate utilizes pertussis toxin-insensitive and -sensitive pathways. J Immunol 1990;144:2719-24.
4. Naccache PH, Grimard M, Roberge CJ, et al: Crystal-induced neutrophil activation. I. Initiation and modulation of calcium mobilization and Superoxide production by microcrystals. Arthritis Rheum 1991;34:333-42.
5. Poubelle PE, De Medicis R, Naccache PH: Monosodium urate and calcium pyrophosphate crystals differentially activate the excitation-response coupling sequence of human neutrophils. Biochem Biophys Res Commun 1987;149:649-57.
6. Naccache PH, Bourgoin S, Plante E, et al: Crystal-induced neutrophil activation. Arthritis Rheum 1993;36:117-25.
7. Naccache PH, Caon AC, Gilbert C, et al: Inhibition of tyrosine phosphorylation by wortmannin in human neutrophils. Dissociation from its inhibitory effects on phosphilipase D. Lab Invest 1993;69:19-23.
8. Gaudry M, Roberge CJ, De Medicis R, Lussier A, Poubelle PE, Naccache PH: Inflammatory microcrystals induce a distinct pattern of tyrosine phosphorylation in human neutrophils. J Clin Invest 1993;91:1649-55.
9. 2+ concentration determinations in neutrophils stimulated by monosodium urate and calcium pyrophosphate crystals: Effect of protein adsorption. J Rheumatol 1994;21:138-44.
10. Burt HM, Jackson JK: Enhancement of crystal induced neutrophil responses by opsonisation of calcium pyrophosphate dihydrate crystals. Ann Rheum Dis 1993;52:599-607.
11. Burt HM, Jackson JK, Dryden P, Salari H: Crystal-induced protein tyrosine phosphorylation in neutrophils and the effect of a tyrosine kinase inhibitor on neutrophil responses. Mol Pharmacol 1993;43:30-6.
12. Winternitz CI, Jackson JK, Burt HM: The interaction of monoclinic calcium pyrophosphate dihydrate crystals with neutrophils. Rheumatol Int 1996;16:101-8.
13. Christianson NO: Pertussis toxin inhibits the FMLP-induced membrane association of protein kinase C in human neutrophils. J Leukocyte Biol 1990;47:60-3.
14. Liang S, Woodlock TJ, Whitin JC, Lichtman MA, Segal GB: Signal transduction in N-formyl-methionyl-leucyl-phenylalanine and concanavalin A stimulated neutrophils: Superoxide production without a rise in intracellular free calcium. J Cell Physiol 1990;145:295-302.
15. Thelen M, Wymann MP, Langen H: Wortmannin binds specifically to 1-phosphatidylinositol 3-kinase while inhibiting guanine nucleotide-binding protein-coupled receptor signaling in neutrophil leukocytes. Proc Nat Acad Sci USA 1994;91:4960-4.
16. Billak MM, Eckel S, Mullmann TJ, Egan RW, Siegel MI: Phosphatidylcholine hydrolysis of phospholipase D determines phosphatidic and diglyceride levels in chemotactic peptide-stimulated human neutrophils. J Biol Chem 1989;264:17069-77.
17. Bonser RW, Thompson NT, Randall RW, Garland LG: Phospholipase D activation is functionally linked to Superoxide generation in the human neutrophil. Biochem J 1989;264:617-20.
18. Ding J, Vlahos CJ, Liu R, Brown RF, Badwey JA: Antagonists of phosphatidylinositol 3-kinase block activation of several novel protein kinases in neutrophils. J Biol Chem 1995;19:11684-91.
19. Vlahos CH, Matter WF, Brown RF, et al: Investigation of neutrophil signal transduction using a specific inhibitor of phosphatidylinositol 3-kinase. J Immunol 1995;154:2413-22.
20. Ding J, Badwey JA: Wortmannin and 1 butanol block activation of a novel family of protein kinases in neutrophils. FEBS Lett 1994;248:149-52.
21. Okada T, Sakuma L, Fukui Y, Hazeki O, Ui M: Blockage of chemotactic peptide-induced stimulation of neutrophils by wortmannin as a result of selective inhibition of phosphatidylinositol 3-kinase. J Biol Chem 1994;5:3563-7.
22. Arcaro A, Wymann MP: Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: The role of phosphatidylinositol 3,4,5-triphosphate in neutrophil responses. Biochem J 1993;296:297-301.
23. Vlahos CJ, Matter WF: Signal transduction in neutrophil activation. Phosphatidylinositol 3-kinase is stimulated without tyrosine phosphorylation. FEBS Lett 1992;309:242-8.
24. Ui M, Okada T, Hazeki K, Hazeki O: Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase. Trends Biochem Sci 1995;20:303-7.
25. Burt HM, Kalkman PH, Maudlin D: Membranolytic effects of crystalline monosodium urate monohydrate. J Rheumatol 1983;10:440-8.
26. Burt HM, Jackson JK: Characterization and membranolytic effects of calcium pyrophosphate dihydrate crystals. J Rheumatol 1987;14:968-73.
27. Kaplan DR, Whitman M, Schaffhausen B, et al: Phosphatidylinositol metabolism and polyoma-mediated transformation. Proc Nat Acad Sci USA 1986;83:3624-8.
28. Gold MR, Chan VW, Turck CW, DeFranco AL: Membrane Ig cross-linking regulates phosphatidylinositol 3-kinase in B lymphocytes. J Immunol 1992;148:2012-22.
29. Burt HM, Jackson JK, Salari H: Inhibition of crystal-induced neutrophil activation by a protein tyrosine kinase inhibitor. J Leukocyte Biol 1994;55:112-9.
30. Bonser RW, Thompson NT, Randall RW, et al: Demethoxyviridin and wortmannin block phospholipase C and D activation in the human neutrophil. Br J Pharmacol 1991;103:1237-41.
31. Vlahos CJMWF, Hui KY, Brown RF: A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY 294002). J Biol Chem 1994;269:5241-8.
32. Scheid MP, Duronio V: Phosphatidylinositol 3-OH kinase activity is not required for the activation of mitogen-activated protein kinase by cytokines. J Biol Chem 1996;271:18134-9.
33. Thelen M, Peveri P, Kernen P, von Tscharner V, Walz A, Baggiolini M: Mechanism of neutrophil activation by NAF, a novel monocyte-derived peptide agonist. FASEB J 1988;2:2702-6.
34. Dewald B, Thelen M, Baggiolini M: Two transduction sequences are necessary for neutrophil activation by receptor agonists. J Biol Chem 1988;263:16179-84.
35. Baggiolini M, Dewald B, Schnyder J, Ruch W, Cooper PH, Payne TG: Inhibition of the phagocytosis-induced respiratory burst by the fungal metabolite wortmannin and some analogues. Exp Cell Res 1987;169:408-18.
36. Kessels GCR, Krause KH, Verhoeven AJ: Protein kinase C activity is not involved in N-formylmethionyl-leucyl-phenylalanine-induced phospholipase D activation in human neutrophils, but is essential for concomitant NADPH oxidase activation: Studies with a staurosporine analogue with improved selectivity for protein kinase C. Biochemical J 1993;292:781-5.
37. Nakanishi S, Yano H, Matsuda Y: Novel functions of a phosphatidylinositol 3-kinase in terminally differentiated cells. Cell Signal 1995;7:545-57.
38. Nakanishi H, Brewer KA, Exton JH: Activation of the z isozyme of protein kinase C by phosphatidylinositol 3,4,5-triphosphate. J Biol Chem 1993;268:13-6.
39. Jackson TR, Stephens LR, Hawkins PT: Receptor specificity on growth factor-stimulated synthesis of 3-phosphorylated inositol lipids in Swiss 3T3 cells. J Biol Chem 1992;267:16627-36.
40. Majumdar S, Kane LH, Rossi MW, Volpp BD, Nauseef WM, Korchak HM: Protein kinase C isotypes and signal transduction in human neutrophils: Selective substrate specificity of calcium-dependent b-PKC and novel calcium-independent n-PKC. Biochim Biophys Acta 1993;1176:276-86.