Synthesis of exo-3-hydroxy-7-azabicyclo[2.2.1]heptane-1-carboxylic acid, a new conformationally constrained 4-hydroxyproline

Synthesis

Volumn , Issue 2, 1997, Pages 165-167

  Avenoza, A ^a   Cativiela, C ^b   Fernandez Recio M A ^a   Peregrina, J M ^a  

^a UNIVERSITY OF LA RIOJA   (Spain)

^b UNIVERSITY OF ZARAGOZA   (Spain)

Author keywords

4 hydroxyproline; 7 azabicyclo 2.2.1 heptane skeleton; intramolecular nucleophilic displacement; iodo 1,3 oxazine intermediate

Indexed keywords

3 HYDROXY 7 AZABICYCLO[2.2.1]HEPTANE 1 CARBOXYLIC ACID; AMINO ACID DERIVATIVE; CYCLOHEXANECARBOXYLIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; IN VITRO STUDY; REACTION ANALYSIS; STEREOCHEMISTRY;

EID: 0031051683     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-1997-1169     Document Type: Article

References (35)

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35. w-values of 0.0796 and 0.1082 respectively. Complete data have been deposited at the Cambridge Crystallographic Data Centre.