Intravenous alpha-1-antitrypsin replacement therapy: Case report after one year of treatment

Irish Journal of Medical Science

Volumn 166, Issue 1, 1997, Pages 7-9

  Ward, A C ^a   Keogh, B A ^a  

^a MATER MISERICORDIAE UNIVERSITY HOSPITAL   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ANTITRYPSIN;

ADULT; ALPHA 1 ANTITRYPSIN DEFICIENCY; ARTICLE; AUTOSOMAL DISORDER; CASE REPORT; EMPHYSEMA; HOMOZYGOTE; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; IRELAND; LUNG FUNCTION TEST; MALE; SUBSTITUTION THERAPY;

EID: 0031051333     PISSN: 00211265     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02939766     Document Type: Article

References (10)

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3. Buist, A. S. Alpha-1-antitrypsin deficiency - Diagnosis, treatment and control: Identification of patients. Lung 1990; Suppl. 543-51.
4. Wewers, M. D., Casolaro, M. A., Sellers, S. E. et al. Replacement therapy for alpha-1-antitrypsin deficiency associated with emphysema. NEJM 1987; 316: 1055-62.
5. Guidelines for the approach to the patient with severe hereditary alpha-1-antitrypsin deficiency - Official statement of the ATS. Am. Rev. Respir. Dis. 1989; 140: 1494-97.
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8. Brantly, M. L., Paul, L. D., Miller, B. H., Falk, R. T., Wu, M., Crystal, R. G. Clinical features and history of the destructive lung disease associated with alpha-1-antitrypsin deficiency of adults with pulmonary symptoms. Am. Rev. Respir. Dis. 1988; 138: 327-336.
9. Hubbard, R. C., McElvaney, N. G. Sellers, S. E., Healy, J. T., Czerski, D. B., Crystal, R. G. Recombinant DNA-produced alpha-1-antitrypsin administered by aerosol augments lower respiratory tract anti-neutrophil elastase defences in individuals with alpha-1-antitrypsin deficiency. J. Clin. Invest. 1989; 84: 1349-54.
10. Hubbard, R. C., Sellers, S., Czerski, D., Stephens, L., Crystal, R. G. Biochemical efficacy and safety of monthly augmentation therapy for alpha-1-antitrypsin deficiency. JAMA 1988, 260: 1259-64.