Identification of a novel transferable cis element in the promoter of an estrogen-responsive gene that modulates sensitivity to hormone and antihormone

Molecular Endocrinology

Volumn 11, Issue 3, 1997, Pages 330-341

  Montano, Monica M ^a   Kraus, W Lee ^a,c   Katzenellenbogen, Benita S ^a,b  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN; ESTROGEN RECEPTOR; PROGESTERONE RECEPTOR;

ARTICLE; DNA DRUG COMPLEX; ESTROGEN METABOLISM; HORMONE RECEPTOR INTERACTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; REPORTER GENE; TRANSCRIPTION REGULATION;

EID: 0031051102     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/mend.11.3.9899     Document Type: Article

References (44)

1. Beato M, Herrlich P, Schütz G 1995 Steroid hormone receptors: many actors in search of a plot. Cell 83:851-857
2. Green S, Chambon P 1991 The oestrogen receptor: from perception to mechanism. In: Parker M (ed) Nuclear Hormone Receptors. Academic Press, New York, pp 15-38
3. Katzenellenbogen BS, Bhardwaj B, Fang H, Ince BA, Pakdel F, Reese JC, Schodin DJ, Wrenn CK 1993 Hormone binding and transcription activation by estrogen receptors: analyses using mammalian and yeast systems. J Steroid Biochem Mol Biol 47:39-48
4. Tsai M-J, O'Malley BW 1994 Molecular mechanisms of action of steroid/thyroid receptor superfamily members. Annu Rev Biochem 63:451-486
5. Katzenellenbogen JA, O'Malley BW, Katzenellenbogen BS 1996 Tripartite steroid hormone receptor pharmacology: interaction with multiple effector sites as a basis for the cell- and promoter-specific action of these hormones. Mol Endocrinol 10:119-131
6. Katzenellenbogen BS, Montano M, Le Goff P, Schodin DJ, Kraus WL, Bhardwaj B, Fujimoto N 1995 Antiestrogens: mechanisms and actions in target cells. J Steroid Biochem Mol Biol 53:387-393
7. Berry M, Metzger D, Chambon P 1990 Role of the two activating domains of the oestrogen receptor in the cell-type and promoter-context dependent agonistic activity of the anti-oestrogen 4-hydroxytamoxifen. EMBO J 9:2811-2818
8. Montano MM, Müller V, Trobaugh A, Katzenellenbogen BS 1995 The carboxyl-terminal F domain of the human estrogen receptor: role in the transcriptional activity of the receptor and the effectiveness of antiestrogens as estrogen antagonists. Mol Endocrinol 9:814-825
9. Tzukerman MT, Esty A, Santiso-Mere D, Danielian P, Parker MG, Stein RB, Pike JW, McDonnell DP 1994 Human estrogen receptor transactivational capacity is determined by both cellular and promoter context and mediated by two functionally distinct intramolecular regions. Mol Endocrinol 8:21-30
10. Kraus WL, Montano MM, Katzenellenbogen BS 1993 Cloning of the rat progesterone receptor gene 5́ region and identification of two functionally distinct promoters. Mol Endocrinol 7:1603-1616
11. Kraus WL, Montano MM, Katzenellenbogen BS 1994 Identification of multiple, widely spaced estrogen-responsive regions in the rat progesterone receptor gene. Mol Endocrinol 8:952-969
12. Brown AMC, Jeltsch JM, Roberts M, Chambon P 1984 Activation of pS2 gene transcription is a primary response to estrogen in the human breast cancer cell line MCF-7. Proc Natl Acad Sci USA 81:6344-6348
13. Corthesy B, Cardinaux JR, Claret FX, Wahli W 1989 A nuclear factor I-like activity and a liver-specific repressor govern estrogen-regulated in vitro transcription from the Xenopus laevis vitellogenin B1 promoter. Mol Cell Biol 9:5548-5562
14. Kumar V, Green S, Stack G, Berry M, Jin JR, Chambon P 1987 Functional domains of the human estrogen receptor. Cell 51:941-951
15. Fujimoto N, Katzenellenbogen BS 1994 Alteration in the agonist/antagonist balance of antiestrogens by activation of protein kinase A signaling pathways in breast cancer cells: antiestrogen-selectivity and promoter-dependence. Mol Endocrinol 8:296-304
16. Oshima H, Simons Jr SS 1992 Modulation of transcription factor activity by a distant steroid modulatory element. Mol Endocrinol 6:416-428
17. Simons Jr SS, Oshima H, Szapary D 1992 Higher levels of control: modulation of steroid hormone-regulated gene transcription. Mol Endocrinol 6:995-1002
18. Depasquale JA, Samsonoff WA, Gierthy JF 1994 17-β-estradiol induced alterations of cell-matrix and intercellular adhesions in a human mammary carcinoma cell line. Science 107:1241-14254
19. Ali S, Metzger D, Bornert JM, Chambon P 1993 Modulation of transcriptional activation by ligand-dependent phosphorylation of the human oestrogen receptor A/B region. EMBO J 12:1153-1160
20. Arnold SF, Obourn JD, Jaffe H, Notides AC 1994 Serine 167 is the major estradiol-induced phosphorylation site on the human estrogen receptor. Mol Endocrinol 8:1208-1214
21. Le Goff P, Montano MM, Schodin DJ, Katzenellenbogen BS 1994 Phosphorylation of the human estrogen receptor: identification of hormone-regulated sites and examination of their influence on transcriptional activity. J Biol Chem 269:4458-4466
22. Freedman LP, Luisi BF 1993 On the mechanism of DNA binding by nuclear hormone receptors: a structural and functional perspective. J Cell Biochem 51:140-150
23. Martinez E, Wahli W 1991 Characterization of hormone response elements. In: Parker M (ed) Nuclear Hormone Receptors. Academic Press, New York, pp 125-151
24. Baniahmad C, Nawaz Z, Baniahmad A, Gleeson MAG, Tsai M-J, O'Malley BW 1995 Enhancement of human estrogen receptor activity by SPT6: a potential coactivator. Mol Endocrinol 9:34-43
25. Cavaillés V, Dauvois S, L'Horset F, Lopez G, Hoare S, Kushner PJ, Parker MG 1995 Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor. EMBO J 14:3741-3751
26. Halachmi S, Marden E, Martin G, MacKay H, Abbondanza C, Brown M 1994 Estrogen receptor-associated proteins: possible mediators of hormone-induced transcription. Science 264:1455-1458
27. Le Douarin B, Zechel C, Garnier J, Luyz Y, Tora L, Pierrat B, Heery D, HG, Chambon P, Losson R 1995 The N-terminal part of TIF1, a putative metiator of the ligand-dependent activiation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18. EMBO J 14:2020-2033
28. Onate SA, Tsai SY, Tsai MJ, O'Malley BW 1995 Sequence and characterization of a coactivator for the steroid hormone receptor superfamily. Science 270:1354-1357
29. Horwitz KB, Jackson TA, Bain DL, Richer JK, Takimoto GS, Tung T 1996 Nuclear receptor coactivators and corepressors. Mol Endocrinol 10:1167-1177
30. Burbach JP, da Silva SL, Cox JJ, Adan RA, Cooney AJ, Tsai M, Tsai S 1994 Repression of estrogen-dependent stimulation of the oxytocin gene by chicken ovalbumin promoter transcription factor I. J Biol Chem 269:15046-15053
31. Kraus WL, Weis KE, Katzenellenbogen BS 1995 Inhibitory cross-talk between steroid hormone receptors: differential targeting of estrogen receptor in the repression of its transcriptional activity by agonist- and antagonist-occupied progestin receptors. Mol Cell Biol 15:1847-1857
32. Liu Y, Yang N, Teng CT 1993 COUP-TF acts as a competitive repressor for estrogen receptor-mediated activation of the mouse lactoferrin gene. Mol Cell Biol 13:1836-1846
33. McDonnell DP, Goldman ME 1994 RU486 exerts antiestrogenic activities through a novel progesterone receptor A form-mediated mechanism. J Biol Chem 269:11945-11949
34. Chiba H, Muramatsu M, Nomoto A, Kato H 1994 Two human homologues of Saccharomyces cerevisiae SW12/ SNF2 and Drosophila brahma are transcriptional coactivators cooperating with the estrogen receptor and the retinoic acid receptor. Nucleic Acids Res 22:1815-1820
35. Gothard LQ, Hibbard JC, Seyfred MA 1996 Estrogenmediated induction of rat prolactin gene transcription requires the formation of a chromatin loop between the distal enhancer and proximal promoter regions. Mol Endocrinol 10:185-195
36. Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA, Struhl K 1992 Short Protocols in Molecular Biology, ed 2. John Wiley & Sons, New York
37. Sambrook J, Fritsch EF, Maniatis T 1989 Molecular Cloning: A Laboratory Manual, ed 2. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
38. Aronica SM, Kraus WL, Katzenellenbogen BS 1994 Estrogen action via the cAMP signaling pathway: stimulation of adenylate cyclase and cAMP-regulated gene transcription. Proc Natl Acad Sci USA 91:8517-8521
39. Kunkel TA 1985 Rapid and efficient site-specific mutagenesis without phenotypic selection. Proc Natl Acad Sci USA 82:488-492
40. Mead D, Szczesna-Skorupa E, Kemper B 1986 Single-stranded DNA 'blue' T7 promoter plasmids: a versatile tandem promoter system for cloning and protein engineering. Protein Eng 1:67-74
41. Clarke R, Brünner N, Katzenellenbogen BS, Thompson EW, Norman MJ, Koppi C, Soonmyoung P, Lippman ME, Dickson RB 1989 Progression of human breast cancer cells from hormone-dependent to hormone-independent growth both in vitro and in vivo. Proc Natl Acad Sci USA 86:3649-3653
42. Chen C, Okayama H 1987 High efficiency transformation of mammalian cells by plasmid DNA. Mol Cell Biol 7:2745-2752
43. Reese JC, Katzenellenbogen BS 1991 Mutagenesis of cysteines in the hormone binding domain of the human estrogen receptor: alterations in binding and transcriptional activation by covalently and reversibly attaching ligands. J Biol Chem 266:10880-10887
44. Reese JR, Katzenellenbogen BS 1991 Differential DNA-binding abilities of estrogen receptor occupied with two classes of antiestrogens: studies using human estrogen receptor overexpressed in mammalian cells. Nucleic Acids Res 19:6595-6602