Isolated perfused liver as a tool to study the disposition of peptides, liver first-pass effects, and cell-specific drug delivery

Journal of Controlled Release

Volumn 46, Issue 1-2, 1997, Pages 139-156

  Mejer, D K F ^a,b   Swart, P J ^b  

^a UNIVERSITY OF GRONINGEN   (Netherlands)

^b Utrecht Inst Drug Explor   (Netherlands)

Author keywords

(neo) Glycoproteins; Acinar distribution of asialoglycoprotein receptor; Anti HIV preparation; Antiviral proteins; AZT; Drug targeting to liver; Hepatic disposition of peptides; Hepatic endocytosis; Isolated perfused liver preparation; Lysosomal proteolysis; Mannose receptor; Naproxen; Negatively charged albumins; Oligopeptides

Indexed keywords

ALKALINE PHOSPHATASE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; ANTINEOPLASTIC AGENT; ASIALOGLYCOPROTEIN; ASIALOGLYCOPROTEIN RECEPTOR; CHOLECYSTOKININ OCTAPEPTIDE; DIAGNOSTIC AGENT; DOXORUBICIN; DRUG CARRIER; GLYCOPROTEIN; GROWTH FACTOR; IMMUNOGLOBULIN; LIPOSOME; MANNOSE RECEPTOR; NAPROXEN; OLIGOPEPTIDE; PEPTIDE HORMONE; RENIN INHIBITOR; TRIFLURIDINE; ZIDOVUDINE;

BILIARY EXCRETION; CONFERENCE PAPER; DRUG DISPOSITION; DRUG EXCRETION; DRUG METABOLISM; DRUG TARGETING; DRUG TRANSPORT; ENDOCYTOSIS; HUMAN; ISOLATED LIVER; LIVER PERFUSION; NONHUMAN; PHARMACOKINETICS; PRIORITY JOURNAL;

EID: 0031050615     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(96)01587-8     Document Type: Conference Paper

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