Increased hemorrhagic risk after repeated infusion of highly substituted medium molecular weight hydroxyethyl starch

Arzneimittel-Forschung/Drug Research

Volumn 47, Issue 1, 1997, Pages 18-22

  Treib, Johannes ^a,b   Haass, Anton ^a   Pindur, Gerhard ^a   Grauer, Markus T ^a   Jung, Friedel ^a   Wenzel, Ernst ^a   Schimrigk, Klaus ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

Author keywords

coagulation; hemodilution; hemorheology; hydroxyethyl starch, clinical studies, hemorrhagic risk; plasma substitutes

Indexed keywords

BLOOD CLOTTING FACTOR 12; BLOOD CLOTTING FACTOR 8; BLOOD CLOTTING FACTOR 9; HETASTARCH; VON WILLEBRAND FACTOR; PLASMA SUBSTITUTE;

ADULT; AGED; ARTICLE; CEREBROVASCULAR DISEASE; CLINICAL ARTICLE; CLINICAL TRIAL; DRUG BLOOD LEVEL; FEMALE; HEMODILUTION; HUMAN; MALE; MOLECULAR WEIGHT; PARTIAL THROMBOPLASTIN TIME; THROMBOCYTE AGGREGATION; BLEEDING; BLOOD CLOTTING; BLOOD VISCOSITY; CHEMICALLY INDUCED DISORDER; CHEMISTRY; DRUG EFFECT; HEMATOCRIT; HEMOSTASIS; METABOLISM; MIDDLE AGED; PATHOPHYSIOLOGY; RISK;

BLOOD COAGULATION; BLOOD VISCOSITY; FEMALE; HEMATOCRIT; HEMODILUTION; HEMORRHAGE; HEMOSTASIS; HETASTARCH; HUMANS; MALE; MIDDLE AGED; MOLECULAR WEIGHT; PARTIAL THROMBOPLASTIN TIME; PLASMA SUBSTITUTES; RISK; VON WILLEBRAND FACTOR;

EID: 0031050073     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Strauss, R. G. Tansfusion 21, 299 (1981)
2. Strauss, R. G., Stansfield, C., Henriksen, R. A. et al., Transfusion 28, 257 (1988)
3. Symington, B. E., Ann. Intern. Med. 105, 627 (1986)
4. Damon, L., Adams, M., Stricker, R. B. et al., N. Engl. J. Med. 317, 964 (1987)
5. Bianchine, J. R., N. Engl. Med. 317, 965 (1987)
6. Cully, M. D., Larson, C. P., Silverberg, G. D., Anaesthesiology 66, 707 (1987)
7. Sanfelippo, M. J., Suberviola, P. D., Geimer, N. F., Am. J. Clin. Pathol. 88, 653 (1987)
8. Abramson, N., Ann. Intern. Med. 108, 307 (1988)
9. Lockwood, D. N. J., Bullen, C., Machin, S. J., Anaesthesia 43, 391 (1988)
10. Claes, Y., Van Hemelrijck, J., Van Gerven, M. et al., Anaest. Analg. 75, 24 (1992)
11. Kapiotis, S., Quehenberger, P., Eichler, H. G. et al., Crit. Care. Med. 22, 606 (1994)
12. Trumble, E. R., Muizelaar, J. P., Myseros, J. S. et al., J. Neurosurg. 82, 44 (1995)
13. Treib, J., Haass, A., Pindur, G. et al., Haemostasis 26, 210 (1996)
14. Yoshida, M., Yamashita, T., Matsuo, J. et al., Stärke 25, 373 (1973)
15. Yoshida, M., Kishikawa, T., Starch/Stärke 36, 167 (1984)
16. Yoshida, M., Minami, Y., Kishikawa, T., Starch/Stärke 36, 209 (1984)
17. Haass, A., Kroemer, H., Jäger, H. et al., Dtsch. Med. Wschr. 111, 1681 (1986)
18. Kroemer, H., Haass, A., Müller, K. et al., Eur. J. Clin. Pharmacol. 31, 705 (1987)
19. Jung, F., Koscielny, J., Mrowietz, C. et al., Arzneim.-Forsch./ Drug Res. 43 (I), 99 (1993)
20. Treib, J., Haass, A., Pindur, G. et al., Thromb. Haemostas. 74, 1452 (1995)
21. Treib, J., Haass, A., Pindur, G. et al., Transfusion 36, 450 (1996)
22. Eigner, W-D., Krankenhauspharmazie 9, 20 (1988)
23. Förster, H., Wicarkzyk, C., Dudziak, R., Infusionstherapie 2, 88 (1981)
24. Jung, F., Roggenkamp, H. G., Schneider, R. et al., Biomed. Technik. 28, 249 (1983)
25. Kiesewetter, H., Radtke, H., Schneider, R. et al., Biomed. Technik 27, 209 (1982)
26. Köhler, H., Zschiedrich, H., Clasen, R. et al., Anaesthesist 31, 61 (1982)
27. Kiesewetter, H., Waldhausen, P., Schimetta, W. et al., in: Hemodilution. New aspects in the management of circulatory blood flow, J. Koscielny, H. Kiesewetter, F. Jung, A. Haass (eds.), p. 165, Springer, Berlin-Heidelberg etc. (1992)
28. Haass, A., Treib, J., Stoll, M., Clin. Hemorheol. 12 (Suppl. 1), 17 (1992)
29. Kuitunen, A., Hynynen, M., Salmenperä, M. et al., Acta Anaesthesiol. Scand. 37, 652 (1993)
30. Batlle, J., Del Rio, F., Fernandez, M. F. et al., Thromb. Haemostas. 54, 697 (1985)
31. Siostrzonek, P., Niessner, H., Deutsch, E. et al., in: 16. Hämophilie Symposion, G. Landbeck (ed.), pp. 248-256 Springer, Berlin-Heidelberg etc. (1985)
32. Ruggeri, Z. N., Haemostasis 24, 265 (1994)