Effects of IFN-γ, TNF-α and EGF on the expression of HLA class I antigen and the proliferation of human hepatocellular carcinoma HepG2 cells

Anticancer Research

Volumn 17, Issue 1 A, 1997, Pages 181-188

  Wang, Dongfang ^a   Yang, Erbin ^a   Cheng, Li Yao ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Epidermal growth factor; Interferon; MHC class I antigen; Morphology; Proliferation; Tumor necrosis factor

Indexed keywords

EPIDERMAL GROWTH FACTOR; GAMMA INTERFERON; HLA ANTIGEN CLASS 1; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL PROLIFERATION; CELL STRAIN HEPG2; CELL STRUCTURE; CONTROLLED STUDY; DNA SYNTHESIS; DRUG EFFECT; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; PRIORITY JOURNAL; PROTEIN PROCESSING; RNA TRANSLATION;

CARCINOMA, HEPATOCELLULAR; CELL DIVISION; EPIDERMAL GROWTH FACTOR; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; INTERFERON TYPE II; LIVER NEOPLASMS; RNA, MESSENGER; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0031049874     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. Clemens MJ: Cytokines. BIOS Scientific Publishers Limited, Oxford, U.K., 1991. pp 85-92.
2. Mobus VJ, Asphal W, Knapstein PC and Kreienberg R: Effects of Interferon γ on the proliferation and modulation of cell-surface structures of human ovarian carcinoma cell lines. J Cancer Res Clin Oncol 120: 27-34, 1993.
3. Paul WE: Fundamental Immunology. Raven Press. New York. 1989. pp 621-661.
4. Chester JR, Gaissert HA, Ross, JS and Malt RA: Pancreatic cancer in the Syrian hamster induced by N-Nitrosobis (2-oxopropyl)-amine: cocarcinogenic effect of epidermal growth factor. Cancer Res 46: 2954-2957, 1986.
5. Kingsnorth AN, Abu-Khalaf M, Ross JS and Malt RA: Potentiation of 1.2-dimethyl hydrazine - induced anal carcinoma by epidermal growth factor in mice. Surgery 97: 690-700, 1985.
6. Chakrabarty S, Rajagopal S and Huang S: Expression of antisense epidermal growth factors receptor RNA down modulation the malignant behaviour of human colon cancer cells. Clin Exp Metastasis 13: 191-195, 1995.
7. Bernard DJ, Courjal F, Maurizis JC, Bignon YJ, Chollet P and Plague R: Effect of epidermal growth factor on HLA class I and class II transcription and protein expression in human breast adenocarcinoma. Br J Cancer 66: 88-92, 1992.
8. Kawamoto T, Mendelsohn J, Le A, Sato GH, Lazar CS and Gill GN: Regulation of epidermal growth factor concentration to growth of human epidermoid carcinoma A431 cells. J Biol Chem 259: 7761-7766, 1984.
9. Guzik K and Klein A: Transforming growth factor-β1 stimulates proliferation of Morris hepatoma cell in serum-free soft agar culture system supplemented with EGF and insulin. Cancer Letters 54: 51-56, 1990.
10. Festenstein H and Garrido F: MHC antigens and malignancy. Nature, 322: 502-503, 1986.
11. Petersen BL, Engel AM and Tuul-Madsen H: Tumors developing in nude mice express unusually large amount of MHC class I antigens. APMIS 99: 1111-1119, 1991.
12. Van den Ingh HF, Ruiter DJ and Griffioen G: HLA antigens in colorectal tumours - low expression of HLA class I antigens in mucinous coloreetal carcinomas. Br J Cancer 55: 125-130, 1987.
13. Cardon-Cardo C, Fuks Z and Drobnjak M: Expression of HLA-A,B,C antigens on primary and metastatic tumor cell populations of human carcinomas. Cancer Res 51: 6372-6380, 1991.
14. Festenstein H: The biological consequences of altered MHC expression on tumors. Br Med Bulletin 43: 217-227, 1987.
15. Tanaka K, Hayashi H, Hamada C, Khoury G and Jay G: Expression of major histocompatibility complex class I antigens as a strategy for the potentiation of immune recognition of tumor cells. Proc Natl Acad Sci USA 83: 8723-8727, 1986.
16. Carrel S, Schmidt-Kessen A and Giuffre L: Recombinant interferon-γ can induce the expression of HLA-DR and DC on DR-negative melanoma cell and enhance the expression of HLA-ABC and tumor associated antigens. Eur J Immunol 15: 118-123, 1985.
17. Brigitte DW, Alain I and Philippe K: The regulation and expression of MHC class I genes. Immunology Today 8: 286-292, 1990.
18. Pfizenmaier K, Scheurich P, Schluter C and Kronke M: Tumor necrosis factor enhances HLA-A,B,C and HLA-DR gene expression in human tumor cells. J Immunol 138: 975-980, 1987.
19. Clemens MJ, Morris AG and Gearing AJH: Lymphokins and Interferons. IRL Press, Washington, 1987, pp 195-220.
20. Carpenter G and Cohen S: Epidermal growth factor. Annu Rev Biochem 48: 193-219, 1979.
21. Singletary SE, Frappaz D, Tucker SL, Larry L, Brock WA and Spitzer G: Epidermal growth factor effect on serum-free growth of primary and metastatic Human tumors. Int J Cell Cloning 7: 59-66, 1989.
22. Schlessinger J, Schreiber AB, Levi A, Lax I, Liberman T and Yarden Y: Regulation of cell proliferation by epidermal growth factor. CRC Crit Rev Biochem 76: 93-111, 1983.
23. Fitzpatrick SL, LaChance MP and Schultz GS: Characterization of epidermal growth factor receptor and action on human breast cancer cells in culture. Cancer Res 44: 3442-3447, 1984.
24. Komori A, Yatsunami J, Suganuma M, Okabe S, Abe S, Sakai A, Sasaki K and Fujiki H: Tumor necrosis factor acts as a tumor promoter in BALB/3T3 cell transformation. Cancer Res 53: 1982-1985, 1993.
25. Wu S, Buyer CM, Whitaker RS, Berchuck A, Wiener JR, Weinberg JB and Bast Jr RC: Turner necrosis factor α as an autocrine growth factor for ovarian cancer: Monokine induction of tumor cell proliferation and tumor necrosis factor α expression. Cancer Res 53: 1939-1944, 1993.
26. Yang EB, Wang DF, Mack P and Cheng LY: EGF receptor in human Chang liver and hepatoma HepG2 cells. Biochem Mol Biol Int 38: 813-820, 1996.
27. Wang DF, Yang EB and Cheng LY: Modulation of EGF receptor by tumor necrosis factor-α in human hepatocellular carcinoma HepG2 cells. Anticancer Res 16: 1996. In press.
28. Greiner JW, Horan Hand P, Wunderlich, D and Colcher D: Radioimmunoassay for detection of chances in cell surface tumor antigen expression induced by Interferon. In: Methods in Enzymology (Pestka, S. ed). Academic Press, San Diego, Vol. 119, pp 682-688, 1986.
29. Sambrook J, Fritsch EF and Maniatis T: Molecular Cloning. Cold Spring Harbour Laboratory Press, New York, 1989, pp 7.39-9.57.
30. Hirano F, Tanaka H, Makino Y, Okamoto K, Inaba M, Miura T and Makino I: Regulation of the major histocompatibility complex class 1 mRNA expression by bile acids in cultured human hepatoma cells. Biochem. Biophys. Res Commun 208: 935-942, 1995.
31. Freshney RI: Culture of animal cells: a manual of basic technique. Alan R Liss Inc, New York, pp 236-237, 1987.
32. Bird TA and Saklatvala J: IL-1 and TNF transmodulate growth factor receptor by a protein kinase C-independent mechanism. J Immunol 142: 126-133, 1989.
33. Maio M, Gluwani B, Tombesi S, Langer JA, Duigou GJ, Kerbel RS, Fisher PB and Ferrone S: Differential induction by immune Interferon of the gene products of the HLA-D region on the melanoma cell line MeWo and its metastatic variant Mam 50-10. J Immunol 141: 913-920, 1988.
34. Jabrane-Ferrat N, Faille A, Loiseau P, Poirier O, Charron D and Calvo F: Effect of gamma interferon on HLA class-I and Class-II transcription and protein expression in human breast adenocarcinoma cell lines. Int J Cancer 45: 1169-1176, 1990.
35. Vilcek J, Palombella VJ, Henriksen-Destefano D, Swenson C, Feinman R, Hirai M and Tsujimoto M: Fibroblast growth enhancing activity of tumor necrosis factor and its relationship to other polypeptide growth factors. J Exp Med 163: 632-643, 1986.
36. Sugarman BJ, Aggarwal BB, Hass PE, Figari IS, Palladino MA and Shepard HM: Recombinant human tumor necrosis factor-α: effects on proliferation of normal and transformed cells in vitro. Science 230: 943-945, 1985.
37. Nieburgs AC, Korn JH, Picciano PT and Cohen S: Regulation of growth and mediator production by epidermal growth factor. Cell Immunology 108: 396-404, 1987.
38. Tomooka Y, DiAugustine RP and McLachlan JA: Proliferation of mouse uterine epithelial cells in vitro. Endocrinology 118: 1011-1018, 1986.
39. Gatmaitan Z, Jefferson MD, Ruiz-Opazo N, Biempica L, Arias IM, Dudas G, Leinwand L and Reid LM: Regulation of growth and differentiation of rat hepatoma cell line by synergistic interactions of hormones and collagenous substrata. Cell Biol 97: 1179-1190, 1983.
40. Imagawa W, Tomooka Y, Hamamoto S and Nandi S: Stimulation of mammary epithelial cell growth in vitro: interaction of epidermal growth factor and mammogenic hormones. Endocrinology 116: 1514-1524, 1985.
41. Kamato N, Chida K, Rikimaru K, Horikoshi M and Enomoto S: Growth inhibitory effects of epidermal growth factor and overexpression of its receptors on human squamous cells. Cancer Res 46: 1648-1653, 1986.
42. Haigler HT, Ash JR, Singer SJ and Cohen S: Visualization by fluorescence of the binding and internalization of epidermal growth factor in human carcinoma cells A-431. Proc Natl Acad Sci USA 75: 3317-3321, 1987.