Analysis of the structure of HIV-1 protease complexed with a hexapeptide inhibitor. Part II: Molecular dynamic studies of the active site region

Proteins: Structure, Function and Genetics

Volumn 27, Issue 2, 1997, Pages 195-203

  Geller, Maciej ^a,b   Miller, Maria ^a   Swanson, Stanley M ^c   Maizel, Jacob ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b UNIVERSITY OF WARSAW   (Poland)

^c TEXAS A AND M UNIVERSITY   (United States)

Author keywords

aspartic protease; HIV 1; molecular dynamics; molecular modeling

Indexed keywords

ASPARTIC PROTEINASE INHIBITOR; PROTEINASE INHIBITOR;

ANTIVIRAL ACTIVITY; ARTICLE; DRUG MECHANISM; DRUG PROTEIN BINDING; ENZYME ACTIVE SITE; ENZYME STRUCTURE; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MOLECULAR DYNAMICS; PRIORITY JOURNAL;

BINDING SITES; COMPUTER SIMULATION; ENERGY TRANSFER; HIV PROTEASE; HIV PROTEASE INHIBITORS; HUMANS; HYDROGEN BONDING; MODELS, MOLECULAR; OLIGOPEPTIDES;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0031049559     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0134(199702)27:2<195::AID-PROT5>3.0.CO;2-F     Document Type: Article

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