Effect of tumor necrosis factor-α on the phosphorylation of tyrosine kinase receptors is associated with dynamic alterations in specific protein- tyrosine phosphatases

Journal of Cellular Biochemistry

Volumn 64, Issue 1, 1997, Pages 117-127

  Ahmad, Faiyaz ^a   Goldstein, Barry J ^a,b  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

epidermal growth factor receptor; insulin receptor; insulin resistance; TNF ; tyrosine phosphorylation

Indexed keywords

PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; AUTOPHOSPHORYLATION; ENZYME PHOSPHORYLATION; ENZYME SPECIFICITY; GROWTH REGULATION; HEPATOMA CELL; INSULIN RESISTANCE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PRIORITY JOURNAL; RAT; RECEPTOR GENE; SIGNAL TRANSDUCTION;

ANIMALS; CARCINOMA, HEPATOCELLULAR; CELL DIFFERENTIATION; CELL DIVISION; DRUG RESISTANCE, NEOPLASM; IMMUNOBLOTTING; INSULIN; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN-TYROSINE-PHOSPHATASE; RATS; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, INSULIN; RECEPTORS, CELL SURFACE; SHP1 PROTEIN TYROSINE PHOSPHATASE; SIGNAL TRANSDUCTION; SUBCELLULAR FRACTIONS; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA;

EID: 0031049438     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4644(199701)64:1<117::AID-JCB14>3.0.CO;2-I     Document Type: Article

References (57)

1. Kahn CR (1994): Insulin action, diabetogenes, and the cause of type II diabetes. Diabetes 43:1066-1084.
2. Caro JF (1991): Clinical review 26: Insulin resistance in obese and nonobese man. J Clin Endocrinol Metab 73:691-695.
3. Olefsky JM, Nolan JJ (1995): Insulin resistance and non-insulin-dependent diabetes mellitus: Cellular and molecular mechanisms. Am J Clin Nutr 61:S980-S986.
4. Hotamisligil GS, Spiegelman BM (1994): Tumor necrosis factor alpha: A key component of the obesity-diabetes link. Diabetes 43:1271-1278.
5. Fong Y, Lowry SF (1990): Tumor necrosis factor in the pathophysiology of infection and sepsis. Clin Immunol Immunopathol 55:157-170.
6. Feingold KR, Grunfeld C (1987): Tumor necrosis factor-a stimulates hepatic lipogenesis in the rat in vivo. J Clin Invest 80:184-190.
7. Van der Poll T, Romijn JA, Endert E, Borm JJ, Buller HR, Sauerwein HP (1991): Tumor necrosis factor mimics the metabolic response to acute infection in healthy humans. Am J Physiol 261:E457-E465.
8. Lang CH, Dobrescu C, Bagby GJ (1992): Tumor necrosis factor impairs insulin action on peripheral glucose disposal and hepatic glucose output. Endocrinology 130:43-52.
9. Stephens JM, Carter BZ, Pekala PH, Malter JS (1992): Tumor necrosis factor a-induced glucose transporter (GLUT-1) mRNA stabilization in 3T3-L1 preadipocytes. Regulation by the adenosine-uridine binding factor. J Biol Chem 267:8336-8341.
10. Zhang YH, Lin JX, Yip YK, Vilcek J (1988): Enhancement of cAMP levels and of protein kinase activity by tumor necrosis factor and interleukin 1 in human fibroblasts: Role in the induction of interleukin 6. Proc Natl Acad Sci U S A 85:6802-6805.
11. Vilcek J, Lee TH (1991): Tumor necrosis factor. New insights into the molecular mechanisms of its multiple actions. J Biol Chem 266:7313-7316.
12. Van Lint J, Agostinis P, Vandevoorde V, Haegeman G, Fiers W, Merlevede W, Vandenheede JR (1992): Tumor necrosis factor stimulates multiple serine/threonine protein kinases in Swiss 3T3 and L929 cells. Implication of casein kinase-2 and extracellular signal-regulated kinases in the tumor necrosis factor signal transduction pathway. J Biol Chem 267:25916-25921.
13. Saklatvala J, Rawlinson LM, Marshall CJ, Kracht M (1993): Interleukin 1 and tumour necrosis factor activate the mitogen-activated protein (MAP) kinase in cultured cells. FEBS Lett 334:189-192.
14. Hotamisligil GS, Budavari A, Murray D, Spiegelman BM (1994): Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes - central role of tumor necrosis factor-a. J Clin Invest 94:1543-1549.
15. Hotamisligil GS, Murray DL, Choy LN, Spiegelman BM (1994): Tumor necrosis factor alpha inhibits signaling from the insulin receptor. Proc Natl Acad Sci U S A 91:4854-4858.
16. Feinstein R, Kanety H, Papa MZ, Lunenfeld B, Karasik A (1993): Tumor necrosis factor-alpha suppresses insulin-induced tyrosine phosphorylation of insulin receptor and its substrates. J Biol Chem 268:26055-26058.
17. Hotamisligil GS, Peraldi P, Budavari A, Ellis R, White MF, Spiegelman BM (1996): IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-a and obesity-induced insulin resistance. Science 271: 665-670.
18. Hofmann C, Lorenz K, Braithwaite SS, Colca JR, Palazuk BJ, Hotamisligil GS, Spiegelman BM (1994): Altered gene expression for tumor necrosis factor-alpha and its receptors during drug and dietary modulation of insulin resistance. Endocrinology 134:264-270.
19. Hotamisligil GS, Arner P, Caro JF, Atkinson RL, Spiegelman BM (1995): Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. J Clin Invest 95:2409-2415.
20. Kern PA, Saghizadeh M, Ong JM, Bosch RJ, Deem R, Simsolo RB (1995): The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase. J Clin Invest 95:2111-2119.
21. Goldstein BJ (1993): Regulation of insulin receptor signalling by protein-tyrosine dephosphorylation. Receptor 3:1-15.
22. Goldstein BJ (1996): Protein-tyrosine phosphatases and the regulation of insulin action. In LeRoith D, Olefsky JM, Taylor SI (eds): "Diabetes Mellitus: A Fundamental and Clinical Text." Philadelphia: Lippincott, pp 174-186.
23. Hashimoto N, Feener EP, Zhang WR, Goldstein BJ (1992): Insulin receptor protein-tyrosine phosphatases - leukocyte common antigen-related phosphatase rapidly deactivates the insulin receptor kinase by preferential dephosphorylation of the receptor regulatory domain. J Biol Chem 267:13811-13814.
24. White MF, Kahn CR (1994): The insulin signalling system. J Biol Chem 269:1-4.
25. Streuli M, Krueger NX, Hall LR, Schlossman SF, Saito H (1988): A new member of the immunoglobulin superfamily that has a cytoplasmic region homologous to the leukocyte common antigen. J Exp Med 168:1523-1530.
26. Charbonneau H, Tonks NK, Kumar S, Diltz CD, Harrylock M, Cool DE, Krebs EG, Fischer EH, Walsh KA (1989): Human placenta protein-tyrosine-phosphatase: Amino acid sequence and relationship to a family of receptor-like proteins. Proc Natl Acad Sci U S A 86: 5252-5256.
27. Freeman RM, Plutzky J, Neel BG (1992): Identification of a human src homology 2-containing protein-tyrosine-phosphatase - a putative homolog of drosophila cork-screw. Proc Natl Acad Sci U S A 89:11239-11243.
28. Ahmad S, Banville D, Zhao ZZ, Fischer EH, Shen SH (1993): A widely expressed human protein-tyrosine phosphatase containing src homology-2 domains. Proc Natl Acad Sci U S A 90:2197-2201.
29. Kulas DT, Zhang WR, Goldstein BJ, Furlanetto RW, Mooney RA (1995): Insulin receptor signalling is augmented by antisense inhibition of the protein-tyrosine phosphatase LAR. J Biol Chem 270:2435-2438.
30. Ahmad F, Li PM, Meyerovitch J, Goldstein BJ (1995): Osmotic loading of neutralizing antibodies defines a role for protein-tyrosine phosphatase 1B in negative regulation of the insulin action pathway. J Biol Chem 270:20503-20508.
31. Yamauchi K, Milarski KL, Saltiel AR, Pessin JE (1995): Protein-tyrosine-phosphatase SHPTP2 is a required positive effector for insulin downstream signaling. Proc Natl Acad Sci U S A 92:664-668.
32. Milarski KL, Saltiel AR (1994): Expression of catalytically inactive Syp phosphatase in 3T3 cells blocks stimulation of mitogen-activated protein kinase by insulin. J Biol Chem 269:21239-21243.
33. Noguchi T, Matozaki T, Horita K, Fujioka Y, Kasuga M (1994): Role of SH-PTP2, a protein-tyrosine phosphatase with Src homology 2 domains, in insulin-stimulated ras activation. Mol Cell Biol 14:6674-6682.
34. Xiao S, Rose DW, Sasaoka T, Maegawa H, Burke TR, Roller PP, Shoelson SE, Olefsky JM (1994): Syp (SH-PTP2) is a positive mediator of growth factor-stimulated mitogenic signal transduction. J Biol Chem 269: 21244-21248.
35. Bradford MM (1976): A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254.
36. Laemmli EK (1970): Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
37. Towbin H, Staehelin T, Gordon J (1979): Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci U S A 76:4350-4354.
38. Hashimoto N, Zhang WR, Goldstein BJ (1992): Insulin receptor and epidermal growth factor receptor dephosphorylation by three major rat liver protein-tyrosine phosphatases expressed in a recombinant bacterial system. Biochem J 284:569-576.
39. Harlow E, Lane D (1988): "Antibodies: A Laboratory Manual." Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.
40. Guan KL, Haun RS, Watson SJ, Geahlen RL, Dixon JE (1990): Cloning and expression of a protein-tyrosine-phosphatase. Proc Natl Acad Sci U S A 87:1501-1505.
41. Kasuga M, White MF, Kahn CR (1985): Phosphorylation of the insulin receptor in cultured hepatoma cells and a solubilized system. Methods Enzymol 109:609-621.
42. Pot DA, Woodford TA, Remboutsika E, Haun RS, Dixon JE (1991): Cloning, bacterial expression, purification, and characterization of the cytoplasmic domain of rat LAR, a receptor-like protein tyrosine phosphatase. J Biol Chem 266:19688-19696.
43. Pike LJ, Kuenzel EA, Casnellie JE, Krebs EG (1984): A comparison of the insulin- and epidermal growth factor-stimulated protein kinases from human placenta. J Biol Chem 259:9913-9921.
44. Tonks NK, Diltz CD, Fischer EH (1991): Purification of protein-tyrosine phosphatases from human placenta. Methods Enzymol 201:427-442.
45. Serra-Pages C, Saito H, Streuli M (1994): Mutational analysis of proprotein processing, subunit association, and shedding of the LAR transmembrane protein tyrosine phosphatase. J Biol Chem 269:23632-23641.
46. Yu Q, Lenardo T, Weinberg RA (1992): The N-terminal and C-terminal domains of a receptor tyrosine phosphatase are associated by non-covalent linkage. Oncogene 7:1051-1058.
47. Totpal K, Agarwal S, Aggarwal BB (1992): Phosphatase inhibitors modulate the growth-regulatory effects of human tumor necrosis factor on tumor and normal cells. Cancer Res 52:2557-2562.
48. Steller MA, Mok SC, Yeh J, Fulop V, Anderson DJ, Berkowitz RS (1994): Effects of cytokines on epidermal growth factor receptor expression by malignant trophoblast cells in vitro. J Reprod Med 39:209-216.
49. Donato NJ, Gallick GE, Steck PA, Rosenblum MG (1989): Tumor necrosis factor modulates epidermal growth factor receptor phosphorylation and kinase activity in human tumor cells. Correlation with cytotoxicity. J Biol Chem 264:20474-20481.
50. Donato NJ, Rosenblum MG, Steck PA (1992): Tumor necrosis factor regulates tyrosine phosphorylation on epidermal growth factor receptors in A431 carcinoma cells: Evidence for a distinct mechanism. Cell Growth Differ 3:259-268.
51. Kuhné MR, Pawson T, Lienhard GE, Feng GS (1993): The insulin receptor substrate-1 associates with the SH2-containing phosphotyrosine phosphatase Syp. J Biol Chem 268:11479-11481.
52. Lechleider RJ, Freeman RM, Neel BG (1993): Tyrosyl phosphorylation and growth factor receptor association of the human corkscrew homologue, SH-PTP2. J Biol Chem 268:13434-13438.
53. Vogel W, Lammers R, Huang JT, Ullrich A (1993): Activation of a phosphotyrosine phosphatase by tyrosine phosphorylation. Science 259:1611-1614.
54. Kuhné MR, Zhao ZZ, Rowles J, Lavan BE, Shen SH, Fischer EH, Lienhard GE (1994): Dephosphorylation of insulin receptor substrate 1 by the tyrosine phosphatase PTP2C. J Biol Chem 269:15833-15837.
55. Serra-Pages C, Kedersha NL, Fazikas L, Medley Q, Debant A, Streuli M (1995): The LAR transmembrane protein tyrosine phosphatase and a coiled-coil LAR-interacting protein colocalize at focal adhesions. EMBO J 14:2827-2838.
56. Bernier M, Liotta AS, Kole HK, Shock DD, Roth J (1994): Dynamic regulation of intact and C-terminal truncated insulin receptor phosphorylation in permeabilized cells. Biochemistry 33:4343-4351.
57. Mooney RA, Anderson DL (1989): Phosphorylation of the insulin receptor in permeabilized adipocytes is coupled to a rapid dephosphorylation reaction. J Biol Chem 264:6850-6857.