Diminished contact hypersensitivity response in IL-4 deficient mice at a late phase of the elicitation reaction

Scandinavian Journal of Immunology

Volumn 45, Issue 3, 1997, Pages 308-314

  Weigmann, B ^a   Schwing, J ^a   Huber, H ^a   Ross, R ^a   Mossmann, H ^b   Knop, J ^a   Reske Kunz, A B ^a,c  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS   (Germany)

^c UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

1 FLUORO 2,4 DINITROBENZENE; INTERLEUKIN 4; T LYMPHOCYTE RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; CONTACT ALLERGY; CONTROLLED STUDY; DOWN REGULATION; LANGERHANS CELL; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SENSITIZATION; T LYMPHOCYTE SUBPOPULATION;

EID: 0031049408     PISSN: 03009475     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3083.1997.d01-402.x     Document Type: Article

References (41)

1. +) T cells that mediate contact sensitivity to trinitrochlorobenzene express I-A determinants. Cell Immunol 1991;135:27-41.
2. Hauser C. Cultured epidermal Langerhans cells activate effector T cells for contact sensitivity. J Invest Dermatol 1990;95:436-40.
3. Miller SD, Jenkins MK. In vivo effects of GK1.5 (anti-L3T4a) monoclonal antibody on induction and expression of delayed-type hypersensitivity. Cell Immunol 1985;92:414-26.
4. + T cells in murine contact sensitivity revealed by in vivo monoclonal antibody depletion. J Immunol 1990;144:4121-8.
5. + T cells. J Exp Med 1996;183:1001-12.
6. + T helper type 2 cells. J Exp Med 1996;183:759-68.
7. Gautam SC, Chikkala NF, Hamilton TA. Anti-inflammatory action of IL-4. J Immunol 1992;148:1411-15.
8. Salerno A, Dieli F, Sireci O, Bellavia A, Asherson GL. Interleukin-4 is a critical cytokine in contact sensitivity. Immunology 1995;84:404-9.
9. Kühn R, Rajewsky K, Müller W. Generation and analysis of interleukin-4 deficient mice. Science 1991;254:707-10.
10. Kopf M, Le Gros G, Bachmann M, Lamers M, Bluethmann H, Köhler G. Disruption of the murine IL-4 gene blocks Th2 cytokine responses. Nature 1993;362:245-8.
11. Itohara S, Mombaerts P, Lafaille J et al. T cell receptor δ gene mutant mice: independant generation of αβ T cells and programmed rearrangements of γδ TCR genes. Cell 1993;72:337-48.
12. Kaye J, Gillis S, Mizel S et al. Growth of a cloned helper T cell line induced by a monoclonal antibody specific for the antigen receptors: interleukin-1 is required for the expression of the receptors for interleukin-2. J Immunol 1984;133:1339-45.
13. Leo O, Foo M, Sachs DH, Samelson LE, Bluestone JA. Identification of a monoclonal antibody specific for a murine T3 polypeptide. Proc Natl Acad Sci USA 1987;84:1374-8.
14. Goodman T, Lefrancois L. Intraepithelial lymphocytes. Anatomical site, T cell receptor form, dictates phenotype and function. J Exp Med 1989;170:1569-81.
15. + dendritic epidermal cells revealed by Vγ3-specific monoclonal antibody. Proc Natl Acad Sci USA 1989;86:4185-9.
16. Becker D, Mohamadzadeh M, Reske K, Knop J. Increased level of intracellular MHC II molecules in murine Langerhans cells following in vivo and in vitro administration of contact allergens. J Invest Dermatol 1992;99:545-9.
17. Becker D, Reske-Kunz A, Knop J, Reske K. Biochemical properties of MHC class II molecules endogenously synthesized and expressed by mouse Langerhans cells. Eur J Immunol 1991;21:1213-20.
18. Julius MH, Simpson E, Herzenberg LA. A rapid method for the isolation of functional thymus-derived murine lymphocytes. Eur J Immunol 1973;3:645-9.
19. Inaba K, Schuler G, Witner MD, Valinsky J, Atassi B, Steinman RM. Immunologic properties of purified epidermal Langerhans cells. J Exp Med 1986;164:605-13.
20. Aiba S, Katz S. The ability of cultured Langerhans-cells to process and present protein antigens is MHC-dependent. J Immunol 1991;146:2479-87.
21. Dieli F, Asherson GL, Romano GC, Sireci G, Gervasi F, Salerno A. IL-4 is essential for the systemic transfer of delayed hypersensitivity by T cell lines. J Immunol 1994;152:2698-704.
22. Palacios R, Sideras P, von Boehmer H. Recombinant interleukin 4/ BSF-1 promotes growth and differentiation of intrathymic T cell precursors from fetal mice in vitro. EMBO 1987;6:91-5.
23. + T-cell subsets: regulation of differentiation and function. Res Immunol 1991;142:7-9.
24. Fiorentino D, Bond M, Mosmann TR. Two types of murine helper T cell clone. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J Exp Med 1989;170:2081-95.
25. D'Andrea A, Aste-Amezaga M, Valainte N, Ma X, Kubin M, Trinchieri G. Interleukin-10 inhibits lymphocyte IFN-γ production by suppressing natural killer cell stimulatory factor/interleukin-12 synthesis in accessory cells. J Exp Med 1993;178:1041-8.
26. Vercelli D, Jabara HH, Lauener RP, Geha RS. IL-4 inhibits the synthesis of IFN-γ and induces the synthesis of IgE in human mixed lymphocyte cultures. J Immunol 1990;144:570-3.
27. Mosmann TR, Sad S. The expanding universe of T-cell subsets: Th1, Th2 and more. Immunol Today 1996;17:138-46.
28. Berg DJ, Leach MW, Kühn R et al. Interleukin-10 but not interleukin-4 is a natural suppressant of cutaneous inflammatory responses. J Exp Med 1995;182:99-108.
29. Carding SR, Jenkinson EJ, Kingston R, Hayday AC, Bottomly K, Owen JT. Development control of lymphokine gene expression in fetal thymocytes during T-cell ontogeny. Proc Natl Acad Sci USA 1989;86:3342-5.
30. + dendritic epidermal cells of adult mice from fetal thymic precursors. Nature 1990;344:68-70.
31. Payer E, Elbe A, Stingl G. Epidermal T-lymphocytes - ontogeny, features and function. Springer Semin Immunopathol 1992;13:315-31.
32. + cells in interleukin-4 transgenic mice. Eur J Immunol 1995;25:1442-5.
33. + epidermal cells. J Immunol 1986;137:2460-7.
34. Georgopoulos K, Bigby M, Wang J et al. The Ikaros gene is required for the development of all lymphoid lineages. Cell 1994;79:143-56.
35. Grabbe S, Gallo R, Lindgren A, Granstein R. Deficient antigen presentation by Langerhans cells from athymic nu/nu mice. J Immunol 1993;151:3430-9.
36. Müller K, Jaunin F, Masouye I, Saurat J, Hauser C. Th2 cells mediate IL-4 dependent local tissue inflammation. J Immunol 1993;150:5576-84.
37. Mohler KM, Butler LD. Differential production of IL-2 and IL-4 mRNA in vivo after primary sensitization. J Immunol 1990;145:1734-9.
38. Masinovsky B, Urdal D, Gallatin WM. IL-4 acts synergistically with IL-1 beta to promote lymphocyte adhesion to microvascular endothelium by induction of vascular cell adhesion molecule-1. J Immunol 1990;145:2886-95.
39. Hiester A, Metcalf D, Campbell P. Interleukin-4 is chemotactic for mouse macrophages. Cell Immunol 1992;139:72-80.
40. Crawford RM, Finbloom DS, Ohara J, Paul WE, Meltzer MS. B cell stimulatory factor-1 (interleukin 4) activates macrophages for increased tumoricidal activity and expression of Ia antigens. J Immunol 1987;139:135-41.
41. Enk AH, Katz SI. Identification and induction of keratinocyte-derived IL-10. J Immunol 1992;149:92-5.