Pharmacokinetics of intravenous recombinant human granulocyte colony-stimulating factor (rhG-CSF) in children receiving myelosuppressive cancer chemotherapy: Clearance increases in relation to absolute neutrophil count with repeated dosing

American Journal of Hematology

Volumn 54, Issue 2, 1997, Pages 124-130

  Sturgill, Marc G ^a,b   Huhn, Richard D ^b,c   Drachtman, Richard A ^b,c   Ettinger, Alice G ^b,c   Ettinger, Lawrence J ^b,c  

^a RUTGERS UNIVERSITY   (United States)

^b ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^c RUTGERS CANCER INSTITUTE OF NEW JERSEY   (United States)

Author keywords

neutrophils; pharmacokinetics; recombinant human granulocyte colony stimulating factor

Indexed keywords

ANTINEOPLASTIC AGENT; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR;

ADOLESCENT; AREA UNDER THE CURVE; ARTICLE; BONE MARROW SUPPRESSION; CANCER; CANCER CHEMOTHERAPY; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG ELIMINATION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; PHARMACODYNAMICS; PHARMACOKINETICS; PRIORITY JOURNAL; SUBCUTANEOUS DRUG ADMINISTRATION;

ADOLESCENT; ANTINEOPLASTIC AGENTS; BONE MARROW; CHILD; CHILD, PRESCHOOL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GRANULOCYTE COLONY-STIMULATING FACTOR; HUMANS; INJECTIONS, INTRAVENOUS; LEUKOCYTE COUNT; MALE; NEUTROPHILS; RECOMBINANT PROTEINS;

EID: 0031048575     PISSN: 03618609     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-8652(199702)54:2<124::AID-AJH5>3.0.CO;2-Z     Document Type: Article

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