The topoisomerase I gene from Candida albicans

Microbiology

Volumn 143, Issue 2, 1997, Pages 377-386

  Jiang, Weidong ^a   Gerhold, David ^b   Kmiec, Eric B ^b   Hauser, Melinda ^c   Becker, Jeffrey M ^c   Koltin, Yigal ^a  

^a ChemGenics Pharmaceuticals Inc   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

^c UNIVERSITY OF TENNESSEE   (United States)

Author keywords

Candida albicans; Null mutant; TOP1; Virulence

Indexed keywords

DNA TOPOISOMERASE;

AMINO ACID SEQUENCE; ARTICLE; CANDIDA; CELL DIVISION; CELL STRUCTURE; ENZYME STRUCTURE; GENE DISRUPTION; MOLECULAR CLONING; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; VIRULENCE;

CANDIDA ALBICANS; EUKARYOTA; SACCHAROMYCES CEREVISIAE;

EID: 0031048489     PISSN: 13500872     EISSN: None     Source Type: Journal    
DOI: 10.1099/00221287-143-2-377     Document Type: Article

References (18)

1. Becker, J. M., Henry, L. K., Jiang, W. & Koltin, Y. (1995). Reduced virulence of Candida albicans mutants affected in multidrug resistance. Infect Immun 63, 4515-4518.
2. Bulawa, C. E., Miller, D. W., Henry, L. K. & Becker, J. M. (1995). Attenuated virulence of chitin-deficient mutants of Candida albicans. Proc Natl Acad Sci USA 92, 10570-10574.
3. Chen, A. Y. & Liu, L. F. (1994). DNA topoisomerases: essential enzymes and lethal targets. Annu Rev Pharmacol Toxicol 34, 191-218.
4. Christman, M. F., Dietrich, F. S. & Fink, G. R. (1988). Mitotic recombination in the rDNA of S. cerevisiae is suppressed by the combined action of DNA topoisomerases I and II. Cell 55, 413-425.
5. Fonzi, W. A. & Irwin, M. Y. (1993). Isogenic strain construction and gene mapping in Candida albicans. Genetics 134, 717-728.
6. Fostel, J. & Montgomery, D. (1995). Identification of the aminocatechol A-3253 as an in vitro poison of DNA topoisomerase I from Candida albicans. Antimicrob Agents Chemother 39, 586-592.
7. Fostel, J. M., Montgomery, D. A. & Shen, L. L. (1992). Characterization of DNA topoisomerase I from Candida albicans as a target for drug discovery. Antimicrob Agents Chemother 36, 2131-2138.
8. Gerhold, D., Thiyagarajan, M. & Kmiec, E. B. (1994). The topoisomerase I gene from Ustilago maydis: sequence, disruption and mutant phenotype. Nucleic Acids Res 22, 3773-3778.
9. Goto, T. & Wang, J. C. (1985). Cloning of yeast TOP1, the gene encoding DNA topoisomerase I, and construction of mutants defective in both DNA topoisomerase I and DNA topoisomerase II. Proc Natl Acad Sci USA 82, 7178-7182.
10. Kirsch, D. R. & Whitney, R. R. (1991). Pathogenicity of Candida albicans auxotrophic mutants in experimental infections. Infect Immun 59, 3297-3300.
11. Kwon-Chung, K. J. & Bennett, J. E. (1992). Candidiasis. In Medical Mycology, pp. 280-336. Philadelphia: Lea & Febiger.
12. Lee, M. P., Brown, S. D., Chen, A. & Hsieh, T. S. (1993). DNA topoisomerase I is essential in Drosophila melanogaster. Proc Nad Acad Sci USA 90, 6656-6660.
13. Levin, N. A., Bjornsti, M. A. & Fink, G. R. (1993). A novel mutation in DNA topoisomerase I of yeast causes DNA damage and RAD9-dependent cell cycle arrest. Genetics 133, 799-814.
14. Omaha, T., Suzuki, T., Mori, M., Osawa, S., Ueda, T., Watanabe, K. & Nakase, T. (1993). Non-universal decoding of the leucine codon CUG in several Candida species. Nucleic Acids Res 21, 4039-4045.
15. Roca, J. (1995). The mechanisms of DNA topoisomerases. Trends Biochem Sci 20, 156-160.
16. Rosenbluh, A., Mevarech, M., Koltin, Y. & German, J. A. (1985). Isolation of genes from Candida albicans by complementation in Saccharomyces cerevisiae. Mol Gen Genet 200, 500-502.
17. Thrash, C., Bankier, A. T., Barrell, B. G. & Sternglanz, R. (1985). Cloning, characterization, and sequence of the yeast DNA topoisomerase I gene. Proc Natl Acad Sci USA 82, 4374-4378.
18. Uemura, T., Morino, K., Uzawa, S., Shiozaki, K. & Yanagida, M. (1987). Cloning and sequencing of Schizosaccharomyces pombe DNA topoisomerase I gene, and effect of gene disruption. Nucleic Acids Res 15, 9727-9739.