In situ immune responses in Crohn's disease: A comparison with acute and persistent measles virus infection

Journal of Medical Virology

Volumn 51, Issue 2, 1997, Pages 90-100

  Wakefield, A J ^a   Sim, R ^a   Akbar, A N ^a   Pounder, R E ^a   Dhillon, A P ^a  

^a ROYAL FREE HOSPITAL   (United Kingdom)

Author keywords

Crohn's disease; cytotoxic lymphocytes; measles virus

Indexed keywords

ARTICLE; CROHN DISEASE; CYTOTOXICITY; GRANULOMATOUS INFLAMMATION; HUMAN; HUMAN TISSUE; IMMUNE RESPONSE; IN VITRO STUDY; MEASLES; VIRUS INFECTION;

ACUTE DISEASE; ADULT; ANIMALS; ANTIGENS, VIRAL; CROHN DISEASE; FEMALE; HUMANS; MACROPHAGES; MALE; MEASLES; MEASLES VIRUS; MICE; MIDDLE AGED; STAINING AND LABELING; T-LYMPHOCYTES, CYTOTOXIC;

MEASLES VIRUS;

EID: 0031048321     PISSN: 01466615     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-9071(199702)51:2<90::AID-JMV2>3.0.CO;2-M     Document Type: Article

References (26)

1. Aaby P, Bukh J, Lisse IM, Smits AJ (1984): Risk factors in subacute sclerosing panencephalitis: Age-and sex-dependent host reactions or intensive exposure? Reviews of Infectious Diseases 6:239-250.
2. + T cell undergoing apoptosis: a mechanism for T cell clearance during resolution of viral infections. Journal of Experimental Medicine 180:1943-1947
3. Belisito DV, Sanchez MR, Baer RL, Valentine F, Thorbecke GJ (1984): New England Journal of Medicine 310:1279-1282.
4. Boylston AW, Francis ND (1988): Does it matter which cells are infected by the human immunodeficiency virus type I? Journal of Pathology 156:93-96.
5. Bunch C (1983): Leucocytes in health and disease. In Wetherall DJ, Ledingham JGG, Warrell DA (eds): "Oxford Textbook of Medicine," Oxford University Press. (1978): pp 19.86-19.88
6. Cooradia HM, Wesley A, Henderson LG, Brain P, Vos GH, Hallet AF (1978): Alteration in immune responsiveness in acute measles and chronic post-measles chest disease. International Archives of Allergy and Applied Immunology 56:14-23.
7. Dagan R, Phillip M, Sarov I, Skibin A, Epstein S, Kuperman O (1987): Cellular immunity and T-lymphocyte subsets in young children with acute measles. Journal of Medical Virology 22:175-182
8. Ekbom A, Wakefield AJ, Zack M, Adami HO (1994): Perinatal measles infection and subsequent Crohn's disease. Lancet 344:508-510.
9. Gartner S, Markovits P, Markovitz DM, Kaplan M, Gallo RC, Popovic M (1986): The role of mononuclear phagocytes in HTL VIII/LAV infection. Science 233:215-219.
10. + human cytotoxic T cell clones are restricted by class II HLA antigens. Journal of Immunology 133:754-757.
11. Jacobsen S, Rose JW, Flerlage ML (1988): Induction of measles virus-specific cytotoxic T cells by purified measles nucleocapsid and haemagglutinin polypeptides. Viral Immunology 1:153-162.
12. Kangro HO, Chong SKF, Hardiman A, Heath RB, Walker-Smith JA (1990): A prospective study of viral and mycoplasma infections in chronic inflammatory bowel disease. Gastroenterology 98:549-553.
13. Lewin J, Dhillon AP, Sim R, Mazure G, Pounder RE, Wakefield AJ (1995): Persistent measles virus infection of the intestine: Confirmation by immunogold electron microscopy. Gut 36:564-569.
14. Liu CC, Walsh C, Young JDE (1995): Perform: Structure and function. Immunology Today 16:194-201.
15. Miller C, Farringdon CP, Harbert K (1992): The epidemiology of subacute sclerosing penencephalitis in England and Wales 1970-1989. International Journal of Epidemiology 21:998-1119.
16. Miyamoto H, Tanaka T, Kitamoto N, Fukada Y, Shimoyama T (1995): Detection of immunoreactive antigen with a monoclonal antibody to measles virus in tissue from patients with Crohn's disease. Journal of Gastroenterology 30:28-33.
17. Moskophidis D, Lechner F, Pircher H, Zinkernagel RM (1993): Virus persistence in acutely infected immunocompetent mice by exhaustion of antiviral cytotoxic effector T cells. Nature 362:758-760.
18. + memory T cells in measles-seropositive individuals by in vitro peptide stimulation. Clinical and Experimental Immunology 102:40-45
19. Pelton BK, Hylton W, Denman AM (1982). Selective immunosuppressive effects of measles virus infection. Clinical and Experimental Immunology 47:19-26.
20. Savage K, Karaweznski K, El-Batanony M, El-Refaie AO, Khakoo S, Dusheiko G, Dhillon AP (1995): Detection of Hepatitis C viral antigen in frozen liver biopsies. Journal of Pathology 175:147A.
21. Strober W, James SP (1986): The immunological basis of inflammatory bowel disease. Journal of Clinical Immunology 6:415-432.
22. Thompson NP, Montgomery S, Pounder RE, Wakefield AJ (1995): Is measles vaccination a risk factor for inflammatory bowel disease? Lancet 345:1071-1074.
23. von Pirquet (1908): Das verhalten der kutanen tuberculin reaktion wahrend der masern. Deutche Medicine Wochenschrift 341: 1297-1300.
24. Wakefield AJ, Sawyerr AM, Dhillon AP, Pittilo RM, Rowles PM, Lewis AAM, Pounder RE (1989): Pathogenesis of Crohn's disease: Multifocal gastrointestinal infarction. Lancet i:1057-1062.
25. Wakefield AJ, Sankey EA, Dhillon AP, Sim R, Hudson M, Pounder RE (1991): Granulomatous vasculitis in Crohn's disease. Gastroenterology 100:1279-1287
26. Wakefield AJ, Pittilo RM, Sim R, Cosby L, Stephenson JR, Dhillon AP, Pounder RE (1993): Evidence of persistent measles virus infection in Crohn's disease. Journal of Medical Virology 39:344-353.