Inhibitory mechanisms in cerebral ischemia: A brief review

Neuroscience and Biobehavioral Reviews

Volumn 21, Issue 2, 1997, Pages 219-226

  Shuaib, Ashfaq ^a,b   Breker Klassen, Michelle M ^a  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

^b ROYAL UNIVERSITY HOSPITAL   (Canada)

Author keywords

Adenosine Calcium; GABA; Glutamate; Hypoxia; Neuronal rescue; Taurine Therapy

Indexed keywords

2,4 DIAMINO 5 (2,3,5 TRICHLOROPHENYL)PYRIMIDINE; 4 AMINOBUTYRIC ACID; 8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; ADENOSINE; ADENOSINE RECEPTOR BLOCKING AGENT; CALCIUM; GLUTAMIC ACID; LAMOTRIGINE; NORADRENALIN; SEROTONIN; TAURINE;

ANIMAL MODEL; ARTICLE; BRAIN BLOOD FLOW; BRAIN HYPOXIA; BRAIN ISCHEMIA; BRAIN PROTECTION; CALCIUM TRANSPORT; CEREBROVASCULAR DISEASE; CONTROLLED STUDY; HYPOTHERMIA; NERVE CELL LESION; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; STROKE;

ANIMALS; BRAIN ISCHEMIA;

EID: 0031048004     PISSN: 01497634     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0149-7634(96)00012-7     Document Type: Article

References (63)

1. Andiné P., Orwar O., Jacobson I., Sandberg M., Hagberg H. Changes in extracellular amino acids and spontaneous neuronal activity during ischemia and extended reflow in the CA1 of the rat hippocampus. J. Neurochem. 57:1991;222-229.
2. Anonymous. Cardiovascular disease in Canada. Heart and Stroke Foundation, Ottawa, 1993.
3. 1 and calcium antagonist binding sites in selectively vulnerable areas: An autoradiographic study of gerbil brain. J. Neurol. Sci. 106:1991;206-212.
4. Benveniste H., Dreger J., Schousboe A., Diemer N.H. Elevation of extracellular concentration of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis. J. Neurochem. 43:1984;1369-1374.
5. Bielenberg G.W., Burkhardt M. 5-Hydroxytryptamine 1A agonists: A new therapeutic principle for stroke treatment. Stroke. 21:(4):1990;161-163.
6. Blomqvist P., Lindvall O., Wieloch T.W. Lesions of the locus coeruleus system aggravate ischemic damage in the rat brain. Neurosci. Letters. 58:1985;353-358.
7. Bloom F., Iverson L. H3-GABA in nerve terminals of rat cerebral cortex by electron microscopy. Nature. 229:1971;628-630.
8. Bode-Greuel K.M., Klisch J., Horvath E., Glaser T., Traber J. Effects of 5-hydroxytryptamine 1A-receptor agonists on hippocampal damage after transient forebrain ischemia in the Mongolian gerbil. Stroke. 21:(4):1990;164-166.
9. 2+-channel blocker prevents CA1 injury 24 h following severe forebrain ischemia and reduces infarction following focal ischemia. J. Cereb. Blood Flow Metab. 14:1994;903-910.
10. Busto R., Dietrich W.D., Globus M.Y.T., Valdes I., Scheinberg P., Ginsberg M.D. Small differences in intraischemic brain temperature critically determine the extent of ischemic neuronal injury. J. Cereb. Blood Flow Metab. 7:1987;729-738.
11. Busto R., Globus M.Y., Dietrich W.D., Martinez E., Valdes I., Ginsberg M.D. Effects of mild hypothermia on ischemia-induced release of neurotransmitters and free fatty acids in rat brain. Stroke. 20:1989;904-910.
12. Chiamulera C., Albertini P., Velerio E., Reggiani A. Activation of metabotropic receptors has a neuroprotective effect in a rodent model of focal ischemia. Eur. J. Pharmac. 216:1992;335-336.
13. Choi D.W., Rothman S.M. The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death. Ann. Rev. Neurosci. 13:1990;171-182.
14. Dietrich D., Busto R., Valdes I., Loor Y. Effects of normothermic versus mild hyperthermic forebrain ischemia in rats. Stroke. 21:1990;1318-1325.
15. Francis A., Pulsinelli W. The response of GABAergic and cholinergic neurons to transient cerebral ischemia. Brain Res. 243:1982;271-278.
16. Garcia J.H., Anderson M.L. Pathophysiology of cerebral ischemia. CRC Crit. R. Neurobiol. 4:1989;303-324.
17. Ginsberg M.D., Sternau L.L., Globus M.Y.-T., Dietrich W.D., Busto R. Therapeutic modulation of brain temperature: Relevance to ischemic brain injury. Cerebrovasc. Brain Metab. Rev. 4:1992;189-225.
18. Kanthan R., Shuaib A., Griebel R., Miyashita H. Intracerebral human microdialysis: In vivo study of an acute focal iscemic model of the human brain. Stroke. 26:1995;870-873.
19. Kirino T., Robinson H.P.C., Miwa A., Tamura A., Kawai N. Disturbance of membrane function preceding ischemic delayed neuronal death in the gerbil hippocampus. J. Cereb. Blood Flow Metab. 12:1992;408-417.
20. Kitagawa K., Matsumoto M., Oda T., Niinobe M., Hata R., Handa N., Fugunaga R., Isaka Y., Kimura K., Maeda H., Mikoshiba K., Kamada T. Free radical generation during brief periods of cerebral ischemia may trigger delayed neuronal damage. Neurosci. 35:1990;551-558.
21. Koide T., Wieloch T.W., Siesjo B.K. Circulating catecholamines modulate ischemic brain damage. J. Cereb. Blood Flow Metab. 6:1986;559-565.
22. Lal S., Shuaib A., Ijaz S. Beclofen is cytoprotective to cerebral ischemia in gerbils. Neurochem. Res. 20:1995;115-119.
23. Lipton S.A., Rosenberg P.A. Excitatory amino acids as a final common pathway for neurologic disorders. New Engl. J. Med. 330:1994;613-622.
24. Lombardini, J.B. Review: Recent studies on taurine in the central nervous system. In: Lombardini, J.B., ed. Taurine. New York: Plenum Press; 1992:245-251.
25. Lyden P.D., Hedges B. Protective effect of synaptic inhibition during cerebral ischemia in rats and rabbits. Stroke. 23:1992;1463-1469.
26. Matsumoto K., Ueda T., Hashimoto T., Kyriyama K. Ischemic neuronal injury in the rat hippocampus following transient forebrain ischemia: evaluation using in vivo-microdialysis. Brain Res. 543:1991;236-242.
27. 2 adrenergic agonist, dexmedetomidine, selectively attenuates ischemia-induced increases in striatal norepinephrine concentrations. Brain Res. 627:1993;325-329.
28. Meldrum B.S., Swan J.H., Leach M.J., Millan M.H., Gwinn R., Kadota K., Graham S.H., Chen J., Simon R.P. Reduction of glutamate release and protection against ischemic brain damage by BW 1003C87. Brain Res. 593:1992;1-6.
29. Milei J., Ferrira R., Llieuy L., Forcada P., Covarrubias J., Boveris A. Reduction of perfusion injury with preoperative rapid intravenous infusion of taurine during myocardiac revascularization. Am. Heart J. 123:1995;339-345.
30. Mori M., Nishizaki T., Okada Y. Protective effect of adenosine on the anoxic damage of hippocampal slice. Neuroscience. 46:1992;301-307.
31. 2+ influx in the pathogenesis of delayed neuronal death after brief forebrain ischemia in gerbils. Brain Res. 613:1993;181-192.
32. Nitsch C., Goping G., Klatzo I. Preservation of GABAergic perikarya and boutons after transient ischemia in the gerbil hippocampal CA1 field. Brain Res. 495:1989;243-252.
33. 2 adenosine receptor agonist CGS 21680 enhances excitatory transmitter amino acid release from the ischemic rat cerebral cortex. Neurosci. Lett. 138:1992;169-172.
34. Onodera H., Sato G., K ogure K. GABA and benzodiazepine receptors in the gerbil brain after transient ischemia: demonstration by quantitative receptor autoradiography. J. Cereb. Blood Flow Metab. 7:1987;82-88.
35. Phillis J.W., Smith-Barbour M., Perkins L.M., O'Regan M.H. Acetylcholine output from the ischemic rat cerebral cortex: Effects of adenosine agonists. Brain Res. 613:1993;337-340.
36. Phillis J.W., Walter G.A. Effect of a brief hypoxic/hypotensive episode on the in-vivo release of cerebral cortical GABA and glycine. Brain Res. 504:1989;121-123.
37. Poli A., Lucchi R., Vibio M., Barnabei O. Adenosine and glutamate modulate each other's release from rat hippocampal synaptosomes. J. Neurochem. 57:1991;298-306.
38. Ravindran J., Shuaib A., Ijaz S., Galazka P., Ishaqzay R., Miyashita H. High extracellular GABA levels in hippocampus - as a mechanism of neuronal protection in cerebral ischemia in adrenalectomized gerbils. Neurosci. Lett. 176:1994;209-211.
39. Rothman M., Olney J.W. Glutamate and the pathophysiology of hypoxic-ischemic brain damage. Ann. Neurol. 19:1986;105-111.
40. Rudolphi K.A., Schubert P., Parkinson F.E., Fredholm B.B. Neuroprotective role of adenosine in cerebral ischemia. Trends Pharmac. 13:1992;439-445.
41. Schoepp D.D., Conn P.J. Metabotropic glutamate receptors in brain function and pathology. Trends Pharmac. 14:1995;13-20.
42. Shuaib, A.; Ijaz, M.S.; Waqar, T.; Voll, C.; Kanthan, R.; Miyashita, H. Insulin elevates hippocampal GABA levels during ischemia. This is independent of its hypoglycemic effect. Neuroscience (in press); 1995.
43. Shuaib A., Ijaz S., Hasan S., Kalra J. Gamma-vinyl GABA prevents hippocampal and substantia nigra reticulata damage in repetitive transient ischemia in gerbils. Brain Res. 590:1992;13-17.
44. Shuaib A., Ijaz S., Hemmings S., Galazka P., Ishaqzay R., Ravindran J., Miyashita H. A decreased glutamate release during hypothyroidism may contribute to protection in cerebral ischemia. Exp. Neurol. 128:1994;260-265.
45. Shuaib A., Ijaz S., Kalra J., Code W. Repetitive transient forebrain ischemia in gerbils: Delayed neuronal damage in the substantia nigra reticulata. Brain Res. 574:1992;120-124.
46. Shuaib A., Ijaz S., Kalra J., Senthilselvan A., Hemmings S. Hypothyroidism protects the brain from the effects of ischemia. Exp. Neurol. 127:1994;119-125.
47. Shuaib A., Ijaz S., Kanthan R. Chlormethiazole protects the brain from transient forebrain ischemia when used up to four hours after the insult. Neurosci. Lett. 197:1995;109-112.
48. Shuaib A., Ijaz S., Mazagri R., Senthilselvan A. CGS-19755 is neuroprotective during repetitive ischemia: This effect is significantly enhanced when combined with hypothermia. Neuroscience. 56:1993;915-920.
49. Shuaib, A.; Mahmood, R.; Wishat, T.; Kanthan, R.; Murabit, M.; Miyashita, H. Neuroprotective effects of lamotrigine in global ischemia in gerbils. A histological, in-vivo microdialysis, behavioral study. Brain Res. (in press); 1995.
50. Shuaib A., Mazagri R., Ijaz S. GABA agonist "muscimol" is neuroprotective in repetitive transient forebrain ischemia in gerbils. Exp. Neurol. 123:1993;284-288.
51. Shuaib A., Sochocka E., Code W., Hertz L. Hypothermia protects astrocytes during ischemia in cell culture. Neurosci. Lett. 146:1992;69-71.
52. Siesjö B.K. Pathophysiology and treatment of focal cerebral ischemia. Part I: Pathophysiology. J. Neurosurg. 77:1992;169-184.
53. Siesjö B.K., Bengtsson F. Calcium fluxes, calcium antagonists, and calcium-related pathology in brain ischemia, hypoglycemia and spreading depression: A unifying hypothesis. J. Cereb. Blood Flow Metab. 9:1989;127-140.
54. Simpson R.E., O'Regan M.H., Perkins L.M., Phillis J.W. Excitatory transmitter amino acid release from the ischemic rat cerebral cortex: Effects of adenosine receptor agonists and antagonists. J. Neurochem. 58:1992;1683-1690.
55. Sternau L.L., Lust W.D., Ricci A.J., Ratcheson R. Role of GABA in selective vulnerability in gerbils. Stroke. 20:1989;281-287.
56. Sutherland G.R., Peeling J., Lesiuk H.J., Brownstone R.M., Rydzy M., Saunders J.K., Geiger J.D. The effects of caffeine on ischemic neuronal injury as determined by magnetic resonance imaging and histopathology. Neuroscience. 42:1991;171-182.
57. Thompson S.M., Capogna M., Scanziani M. Presynaptic inhibition in the hippocampus. Trends Neurosci. 16:1993;222-227.
58. Valentino K., Newcomb R., Gadbois T., Singh T., Bowersox S., Bitner S., Justice A., Yamashiro D., Hoffman B.B., Ciaranello R., Miljanich G., Ramachandran J. A selective N-type calcium channel antagonist protects against neuronal loss after global cerebral ischemia. Proc. Natl. Acad. Sci. USA. 90:1993;7894-7897.
59. Voll C.L., Auer R.N. The effects of postischemic blood glucose levels on ischemic brain damage in the rat. Ann. Neurol. 24:1988;638-646.
60. White B.C., Grossman L.I., Krause G.S. Brain injury by global ischemia and reperfusion: a theoretical perspective on membrane damage and repair. Neurology. 43:1993;1656-1665.
61. Wiard R.P., Dickerson M.C., Beek O., Norton R., Cooper B.R. Neuroprotective properties of the novel antiepileptic lamotrigine in a gerbil model of global cerebral ischemia. Stroke. 26:1995;466-472.
62. Yager J.Y., Brucklacher R.M., Vannucci R.C. Cerebral energy metabolism during hypoxia-ischemia and early recovery in immature rats. Am. J. Physiol. Heart Circ. Physiol. 262:1992;H672-H677.
63. Zivin J.A., Venditto J.A. Experimental CNS ischemia: Serotonin antagonists reduce or prevent damage. Neurology. 34:1984;469-474.