Serum basic fibroblast growth factor in pediatric Crohn's disease. Implications for wound healing

Digestive Diseases and Sciences

Volumn 42, Issue 2, 1997, Pages 378-386

  Bousvaros, Athos ^a   Zurakowski, David ^a   Fishman, Steven J ^a   Keough, Karen ^a   Law, Terry ^a   Sun, Christina ^a   Leichtner, Alan M ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

angiogenesis; Crohn's disease; fibroblast growth factor; ulcerative colitis

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR;

ABDOMINAL PAIN; ADOLESCENT; ADULT; ARTICLE; CHILD; CROHN DISEASE; ENTERITIS; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; INFANT; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; ULCERATIVE COLITIS;

ADOLESCENT; ADULT; CHILD; CHILD, PRESCHOOL; COLITIS, ULCERATIVE; CROHN DISEASE; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FIBROBLAST GROWTH FACTOR 2; HUMANS; MALE; WOUND HEALING;

EID: 0031047591     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1018882322566     Document Type: Article

References (36)

1. Sartor RB: Current concepts in the etiology and pathogenesis of ulcerative colitis and Crohn's disease. Gastroenterol Clin North Am 24:475-507, 1995
2. Yang H, Rotter JI: Genetic aspects of idiopathic inflammatory bowel disease. In Inflammatory Bowel Disease, 4th ed. JB Kirsner, RG Shorter, (eds). Baltimore, Williams and Wilkins, 1995, pp 301-334
3. Schreiber S, Raedler A, Stenson WF, McDermott RP: The role of the mucosal immune system in inflammatory bowel disease. Gastroenterol Clin North Am 21:451-502, 1992
4. Wakefield AJ, Dhillon AP, Rowles PM, Sawyer AM, Pittilo RM, Lewis AM, Pounder RE: Pathogenesis of Crohn's disease: Multifocal gastrointestinal infarction. Lancet 2:1057-1062, 1989
5. Schweigerer L, Fotsis T: Angiogenesis and angiogenesis inhibitors in pediatric diseases. Eur J Pediatr 151:472-476, 1992
6. Rifkin DB, Moscatelli D: Recent developments in the cell biology of basic fibroblast growth factor. J Cell Biol 106:1-6, 1989
7. Slavin A: Fibroblast growth factors: at the heart of angiogenesis. Cell Biol Int 19:431-444, 1995
8. Friese RE, Maciag T: Molecular mechanisms of angiogenesis: Fibroblast growth factor signal transduction. FASEB J 9:919-925, 1995 (review)
9. Folkman J: Clinical application of research on angiogenesis. N Engl J Med 333:1757-1763, 1995
10. New BA, Yeoman LC: Identification of basic fibroblast growth factor and sensitivity and receptor and ligand expression in human colon tumor cell lines. J Cell Physiol 150:320-326, 1992
11. Nice EC, Fabri L, Whitehead RH, James R, Simpson RJ, Burgess AW: The major colonic cell mitogen extractable from colonie mucosa is an N-terminally extended form of basic fibroblast growth factor. J Biol Chem 22:14425-14430, 1991
12. Cordon-Cardo C, Vlodaavsky I, Haimovitz-Friedman A, Hicklin D, Fuks Z: Expression of basic fibroblast growth factor in human tissues. Lab Invest 63:832-840, 1990
13. Schulze-Orloff K, Risau W, Vollmer E, Sorg C: In situ detection of basic fibroblast growth factor by highly specific antibodies. Am J Pathol 137:85-92, 1990
14. Dignass AU, Tsukenawa S, Podolsky DK: Fibroblast growth factors modulate intestinal epithelial cell growth and migration. Gastroenterology 106:1254-1262, 1994
15. Szabo S, Folkman J, Vattay P, Morales RE, Pinkus G, Kato K: Accelerated healing of duodenal ulcers by oral administration of a mutein of basic fibroblast growth factor in rats. Gastroenterology 106:1106-1111, 1994
16. D'Amore PA, Brown RH, Ku PT, Hoffman EP, Watanabe H, Arahata K, Ishihara T, Folkman J: Elevated serum basic fibroblast growth factor in the serum of patients with Duchenne muscular dystrophy. Ann Neurol 35:362-365, 1994
17. Hyams JS, Ferry GD, Mandel FS, Gryboski JD, Kibort PM, Kirschner BS, Griffiths AM, Katz AJ, Granel RJ, Boyle JT, Michener WM, Levy JS, Lesser ML: Development and validation of a pediatric Crohn's disease activity index. J Pediatr Gastroenterol Nutr 12:439-447, 1991
18. Hyams JS, Fitzgerald JE, Treem WR, Wyzga N, Kreutzer DL: Relationship of functional and antigenic interleukin-6 to disease activity in inflammatory bowel disease. Gastroenterology 104:1285-92, 1993
19. Kozarek RA, Patterson DJ, Gelfand MD, Botoman VA, Ball TJ, Wilske KR: Methotrexate induces clinical and histologic remission in patients with refractory inflammatory bowel disease. Ann Intern Med 110:353-356, 1989
20. Miller RG: Simultaneous Statistical Inference, 2nd ed. New York; Springer-Verlag, 1981, pp 67-73
21. Hamilton LC: Regression with Graphics: A Second Course in Applied Statistics. Belmont, California; Duxbury Press, 1992, pp 163-174
22. Bross DA, Leichtner AM, Zurakowski D, Law T, Bousvaros A: Elevation of serum interleukin-6 but not soluble interleukin-2 receptor in children with Crohn's disease. J Pediatr Gastroenterol Nutr 23:164-171, 1996
23. Olwin BB, Arthur K, Hannon K, Hein P, McFall A, Riley B, Szebenyi G, Zhaohui Zhou, Zuber ME, Rapraeger AC, Fallon JF, Kudla AJ: Role of FGF's in skeletal muscle and limb development. Mol reprod dev 39:90-101, 1994
24. Chua CC, Chua BH, Zhao ZY, Krebs C, Diglio C, Perrin E: Effect of growth factors on collagen metabolism in cultured human heart fibroblasts. Connect Tissue Res 26:271-282, 1991
25. Kennedy SH, Qin H, Lin L, Tan EM: Basic fibroblast growth factor regulates type I collagen and collagenase gene expression in human smooth muscle cells. Am J Pathol 146:764-771, 1995
26. Savage MP, Hart CE, Riley BB, Sasse J, Olwin BB, Fallon JF: Distribution of FGF-2 suggests it has a role in chick limb bud growth. Dev Dyn 198:159-170, 1993
27. Rutland P, Pulleyn LJ, Reardon W, Baraitser M, Hayward R, Jones B, Malcolm S, Winter RM, Oldridge M, Slaney SF, Poole MD, Wilkie AO: Identical mutations in the FGFR2 gene cause both Pfeiffer and Crouzon syndrome phenotypes. Nature Genet 9:173-176, 1995
28. Reidy MA: Neointimal proliferation: The role of basic FGF on vascular smooth muscle proliferation. Thromb Haemost 70:172-176, 1993
29. Mazue G, Bertolero F, Jacob C, Sarminetos P, Ronrucci R: Preclinical and clinical studies with recombinant human basic fibroblast growth factor. Ann NY Acad Sci 638:329-340, 1991
30. Davidson JM, Broadley KN: Manipulation of the wound-healing process with basic fibroblast growth factor. Ann NY Acad Sci 638:306-315, 1991
31. Duensing S, Atzpodien J: Increased intracellular and plasma levels of basic fibroblast growth factor in B-cell chronic lymphocytic leukemia. Blood 85:1978-1980, 1995
32. Nguyen M, Watanabe H, Budson AE, Richie JP, Hayes DF, Folkman J: Elevated levels of an angiogenic peptide, basic fibroblast growth factor, in the urine of patients with a wide spectrum of cancers. J Nat Cancer Inst 86:356-361, 1994
33. Folkman J, Szabo S, Stovroff M, McNeil P, Li M, Shing Y: Duodenal ulcer: Discovery of a new mechanism and development of angiogenic therapy that accelerates healing. Ann Surg 214:414-427, 1991
34. Proujansky R, Carpenter AB: Soluble interleukin-2 receptor as a marker of lymphocyte activation in childhood Crohn's disease. J Pediatr Gastroenterol Nutr 13:277-284, 1991
35. Gilmour HM: Crohn's disease. In Gastrointestinal and Oesophageal Pathology. R Whitehead (ed). Edinburgh, Churchill Livingstone, 1989, pp 458-467
36. Dvorak HF, Brown LF, Detmar M, Dvorak AM: Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis. Am J Pathol 146:1030-1039, 1995