Involvement of non-NMDA and NMDA receptors in glutamate-induced pressor or depressor responses of the pons and medulla

Clinical and Experimental Pharmacology and Physiology

Volumn 24, Issue 1, 1997, Pages 46-56

  Chen, S Y ^a   Wu, W C ^a   Tseng, C J ^a   Kuo, J S ^b   Chai, C Y ^a,c  

^a Institute of Biomedical Science   (Taiwan)

^b TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^c INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

Author keywords

AMPA; D AP5; depressor response; GDEE; glutamate; medulla; NMDA; pons; pressor response; renal nerve; vertebral nerve

Indexed keywords

2 AMINO 5 PHOSPHONOVALERIC ACID; GLUTAMIC ACID; GLUTAMIC ACID DIETHYL ESTER; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ANIMAL EXPERIMENT; ARTERIAL PRESSURE; ARTICLE; CAT; KIDNEY NERVE; MEDULLA OBLONGATA; NONHUMAN; PONS; PRESSOR RESPONSE; PRESSORECEPTOR; SYMPATHETIC NERVE;

EID: 0031047523     PISSN: 03051870     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1440-1681.1997.tb01782.x     Document Type: Article

References (44)

1. Calaresu FR, Yardley CP. Medullary basal sympathetic tone. Ann. Rev. Physiol. 1988; 50: 511-24.
2. Ciriello J, Carverson MM, Polosa C. Function of the ventrolateral medulla in the control of the circulation. Brain Res. Rev. 1986; 11: 359-91.
3. Dampney RAL. Functional organization of central pathways regulating the cardiovascular system. Physiol. Rev. 1994; 74: 323-64.
4. Goodchild AK, Dampney RAL, Bandler R. A method for evoking physiological responses by stimulation of cell bodies, but not axons of passage, within localized regions of the central nervous system. J. Neurosci. Methods 1982; 6: 351-63.
5. Chai CY, Chen SY, Wang SD et al. Precollicular decerebration reduces the pressor responses evoked by stimulation of rostral pons but not medulla in cats. J. Auton. Nerv. Syst. 1993; 46: 147-59.
6. Chai CY, Lin RH, Lin AMY, Pan CM, Lee EHY, Kuo JS. Pressor responses from electrical or glutamate stimulations of the dorsal or ventrolateral medulla. Am. J. Physiol. 1988; 255 (Regulatory Integrative Comp. Physiol. 24): R709-17.
7. Chai CY. The role of different portions of lower brain stem of the cat in central cardiovascular control mechanism. Chin. J. Physiol. 1963; 19: 55-64.
8. Chen SY, Wang SD, Cheng CL, Kuo JS, DeGroat WC, Chai CY. Glutamate activation of neurons in CV-reactive areas of cat brain stem affects urinary bladder motility. Am. J. Physiol. 1993; 265 (Renal Fluid Electrolyte Physiol. 34): F520-9.
9. Su CK, Chen SY, Yang JM et al. Correlation of cardiovascular and respiratory responses to glutamate excitation of pressor areas of the medulla in cats. Chin. J. Physiol. 1992; 35: 279-89.
10. Su CK, Hsieh JH, Lin AMY, Kuo JS, Chai CY. Influence of rostral neural structures on the vasomotor functions of the medulla oblongata. Chin. J. Physiol. 1988; 31: 79-93.
11. Su CK, Lin AMY, Lin RH, Kuo JS, Chai CY. Contribution between dorsal and ventrolateral regions of medulla oblongata in vasomotor function of cat. Brain Res. Bull. 1989; 23: 447-56.
12. Su CK, Yen CT, Hwang JC, Tseng CJ, Kuo JS, Chai CY. Differential effects on sympathetic nerve activities elicited by activation of neurons in the pressor areas of dorsal and rostral ventrolateral medulla in cats. J. Auton. Nerv. Syst. 1992; 40: 141-54.
13. Wang SD, Yen KD, Pan CM, Liu JC, Kuo JS, Chai CY. Descending pressor pathways from the dorsomedial and ventrolateral medulla of cats. Chin. J. Physiol, 1996; 39: 17-28.
14. Foster AC, Fagg GE. Acidic amino acid binding sites in mammalian neuronal membranes: Their characteristics and relationship to synaptic receptors. Brain Res. Rev. 1984; 7: 103-64.
15. Cunningham MD, Ferkany JW, Enna SJ. Excitatory amino acid receptors: A gallery of new targets for pharmacological intervention. Life Sci. 1993; 54: 135-48.
16. Monaghan DT, Bridges RJ, Cotman CW. The excitatory amino acid receptors: Their classes, pharmacology, and distinct properties in the function of the central nervous system. Ann. Rev. Pharmacol. Toxicol. 1989; 29: 365-402.
17. Okada Y, Ninomiya I. Differential cardiac and renal inhibitory and excitatory areas in rabbit hypothalamus. Am. J. Physiol. 1983; 244 (Heart Circ. Physiol. 13): H832-8.
18. Sheardown MJ, Nielsen EØ, Hansen AJ, Jacobsen P, Honoré T. 2,3-Dihydroxy-6-nitro-7-sulfamoylbenzo (F) quinoxaline: A neuroprotectant for cerebral ischemia. Science 1990; 247: 571-4.
19. Honoré T, Davies SN, Drejer J, Fletcher EJ, Jacobsen P, Lodge D, Nielsen FE. Quinoxalinediones: Potent competitive non-NMDA glutamate receptor antagonists. Science 1988; 241: 701-3.
20. Kamosinska B, Nowicki D, Szulczyk A, Szulczyk P. Spinal segmental sympathetic outflow to cervical sympathetic trunk, vertebral nerve, inferior cardiac nerve and sympathetic fibers in the thoracic vagus. J. Auton. Nerv. Syst. 1991; 32: 199-204.
21. Engelsen B. Neurotransmitter glutamate: Its clinical importance. Acta Neurol. Scand. 1986; 74: 337-55.
22. Bazil MK, Gordon FJ. Sympathoexcitation from the rostral ventrolateral medulla is mediated by spinal NMDA receptors. Brain Res. Bull. 1993; 31: 273-8.
23. Kao MC, Lee HK, Chai CY, Wang Y. NMDA antagonists attenuate hypertension induced by carotid clamping in the rostral ventrolateral medulla of rats. Brain Res. 1991; 549: 83-9.
24. Zhang X, Abdel-Rahman AA, Wooles WR. Selective sensitization by L-glutamate of baroreflex-mediated bradycardia following microinjection into the rostral ventrolateral medulla. Brain Res. 1990; 520: 141-50.
25. Davies J, Watkins JC. Selective antagonism of amino acid-induced and synaptic excitation in the cat spinal cord. J. Physiol. 1979; 297: 621-35.
26. Talman WT, Granata AR, Reis DJ. Glutamatergic mechanisms in the nucleus tractus solitarius in blood pressure control. Federation Proc. 1984; 43: 39-44.
27. Nagashima C, Iwama K. Electrical stimulation of the stellate ganglion and the vertebral nerve. J. Neurosurg. 1972; 36: 756-62.
28. Berman AL. The Brain Stem of the Cat: A Cytoarchitectonic Atlas with Stereotaxic Coordinates. The University of Wisconsin Press, London, 1968.
29. Gieroba ZJ, Blessing WW. Blockade of excitatory amino acid receptors in the ventrolateral medulla does not abolish the cardiovascular actions of L-glutamate. Naunyn-Schmiedeberg's Arch. Pharmacol. 1993; 347: 66-72.
30. Haldeman S, McLennan H. The antagonistic action of glutamic acid diethylester towards amino acid induced and synaptic excitation of central neurons. Brain Res. 1972; 45: 292-400.
31. Snedecor GM, Cochran WG. Statistical Methods, 7th edn. Iowa State Univ. Press, Ames, Iowa. 1990.
32. McLennan H, Lodge D. The antagonism of amino acid-induced excitation of spinal neurons in the cat. Brain Res. 1979; 169: 83-90.
33. Zieglgäsberger W, Puil EA. Intracellular investigations on the effects of microelectrophoretically applied glutamate antagonists upon neurons of the cat. Naunyn-Schmiedeberg's Arch. Pharmacol. 1973; 277 (Suppl.): R89.
34. Agarwal SK, Gelsema AJ, Calaresu FR. Neurons in rostral VLM are inhibited by chemical stimulation of caudal VLM in rats. Am. J. Physiol. 1989; 257 : R265-70.
35. Cravo SL, Morrison SF. The caudal ventrolateral medulla is a source of tonic sympathoinhibition. Brain Res. 1993; 621: 133-6.
36. Gebber GL, Barman SM. Lateral tegmental field neurons of cat medulla: A potential source of basal sympathetic nerve discharge. J. Neurophysiol. 1985; 54: 1498-512.
37. Goodchild AK, Dampney RAL. A vasopressor cell group in the rostral dorsomedial medulla of the rabbit. Brain Res. 1985; 360: 24-32.
38. Wang MR, Chai CY, Kuo JS. The increase of femoral arterial flow by stimulating the dorsal and ventral medulla in cats. Clin. Exp. Pharmacol. Physiol. 1994; 21: 21-9.
39. Hirooka Y, Polson JW, Dampney RAL. Pressor response from rostral dorsomedial medulla is mediated by excitatory amino acid receptors in rostral VLM. Am. J. Physiol. 1994; 267 (Regulatory Integrative Comp. Physiol. 36): R309-15.
40. Morrison SF, Callaway J, Milner TA, Reis DJ. Rostral ventrolateral medulla: A source of the glutamatergic innervation of the sympathetic intermediolateral nucleus. Brain Res. 1991; 562: 126-35.
41. Miura M, Takayama K, Okada J. Difference in sensitivity of cardiovascular and respiratory control neurons in the subretrofacial nucleus to glutamate receptor subtype agonists in SHR, WKY and cats. J. Auton. Nerv. Syst. 1991; 36: 1-12.
42. Kubo T, Kihara M. N-methyl-D-aspartate receptors mediate tonic vasodepressor control in the caudal ventrolateral medulla of the rat. Brain Res. 1988; 451: 366-70.
43. Blessing WW. Baroreceptor-vasomotor reflex after N-methyl-D-aspartate receptor blockade in rabbit caudal ventrolateral medulla. J. Physiol. 1989; 416: 67-78.
44. Meckler RL, Weaver LC. Splenic, renal, and cardiac nerves have unequal dependence upon tonic supraspinal inputs. Brain Res. 1985; 338: 123-35.