Alterations of the benzodiazepine site of rat α6β2γ2-GABA(A) receptor by replacement of several divergent amino-terminal regions with the α1 counterparts

British Journal of Pharmacology

Volumn 120, Issue 4, 1997, Pages 559-564

  Im, Wha Bin ^a   Pregenzer, Jeffrey F ^a   Binder, Jay A ^a   Alberts, Glen L ^a   Im, Haesook K ^a  

^a PFIZER INC   (United States)

Author keywords

Benzodiazepine site; Cloned GABA(A) receptors; GABA sensitivity; GABA(A) receptor mutants; Ro 15 1788

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; 4 ETHYL 6,7 DIMETHOXY BETA CARBOLINE 3 CARBOXYLIC ACID METHYL ESTER; BENZODIAZEPINE DERIVATIVE; DIAZEPAM; FLUMAZENIL; RECEPTOR SUBTYPE;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; RAT;

AMINO ACID SEQUENCE; ANIMALS; BENZODIAZEPINES; BINDING SITES; CELL LINE; CHLORIDE CHANNELS; GAMMA-AMINOBUTYRIC ACID; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PATCH-CLAMP TECHNIQUES; RATS; RECEPTORS, GABA-A; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0031047013     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0700931     Document Type: Article

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