Expression of scatter factor and c-met receptor in benign and malignant breast tissue

Cancer

Volumn 79, Issue 4, 1997, Pages 749-760

  Jin, Liang ^a   Fuchs, Alexander ^a   Schnitt, Stuart J ^b   Yao, Yan ^a   Joseph, Ansamma ^a   Lamszus, Katrin ^a   Park, Morag ^c   Goldberg, Itzhak D ^a   Rosen, Eliot M ^a,d  

^a LONG ISLAND JEWISH MEDICAL CENTER   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c ROYAL VICTORIA HOSPITAL   (Canada)

^d AMERICAN HEART ASSOCIATION   (United States)

Author keywords

c met receptor, carcinoma; ductal carcinoma in situ; ductal hyperplasia mammary epithelium; hepatocyte growth factor; infiltrating ductal carcinoma; scatter factor

Indexed keywords

MESSENGER RNA; ONCOPROTEIN; PROTEIN TYROSINE KINASE; SCATTER FACTOR;

ARTICLE; BREAST CARCINOMA; BREAST EPITHELIUM; BREAST HYPERPLASIA; CARCINOMA IN SITU; CLINICAL PROTOCOL; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOPEROXIDASE STAINING; IN SITU HYBRIDIZATION; PRIORITY JOURNAL; PROTO ONCOGENE;

EID: 0031046551     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1097-0142(19970215)79:4<749::aid-cncr12>3.0.co;2-%23     Document Type: Article

References (37)

1. Stoker M, Gherardi E, Perryman M, Gray J. Scatter factor is a fibroblast-derived modulator of epithelial cell mobility. Nature 1987;327:238-242.
2. Nakamura T, Nishizawa T, Hagiya M, Seki T, Shimonishi M, Sugimura A, et al. Molecular cloning and expression of human hepatocyte growth factor. Nature 1989;342:440-443.
3. Rosen EM, Nigam SK, Goldberg ID. Scatter factor and the c-met receptor: a paradigm for mesenchymal/epithelial interaction. J Cell Biol 1994;127:1783-7.
4. Rosen EM, Goldberg ID. Scatter factor and angiogenesis. Adv Cancer Res 1995;67:257-79.
5. Bottaro DP, Rubin JS, Faletto DL, Chan AM-L, Kmiecik TE, Vande Woude GF, Aaronson SA. Identification of the hepatocyte growth factor receptor as the c-met proto-oncogene product. Science 1991;251:802-4.
6. Rosen EM, Goldberg ID, Liu D, Setter E, Donovan MA, Bhargava M, et al. Tumor necrosis factor stimulates epithelial tumor cell motility. Cancer Res 1991;57:5315-21.
7. Rosen EM, Knesel J, Goldberg ID, Bhargava M, Joseph A, Zitnik R, et al. Scatter factor modulates the metastatic phenotype of the EMT6 mouse mammary tumor. Int J Cancer 1994;57:706-14.
8. Joseph A, Weiss GH, Jin L, Fuchs A, Chowdhury S, O'Shaugnessy P, et al. Expression of scatter factor in human bladder carcinoma. J Natl Cancer Inst 1995;87:372-7.
9. Wilson SE, Weng J, Chwang EL, Gollahon L, Leitch AM, Shay JW. Hepatocyte growth factor (HGF), keratinocyte growth factor (KGF), and their receptors in human breast cells and tissues: alternative receptors. Cell Mol Biol Res 1994;40:337-50.
10. Yamashita J, Ogawa M, Yamashita S, Nomura K, Kuramoto M, Saishoji T, et al. Immunoreactive hepatocyte growth factor is a strong and independent predictor of recurrence and survival in human breast cancer. Cancer Res 1994;54:1630-3.
11. Mark MR, Lokker NA, Zioncheck TF, Luis EA, Godowski PJ. Expression and characterization of hepatocyte growth factor receptor-IgG fusion proteins. Effects of mutations in the potential proteolytic cleavage sites on processing and ligand binding. J Biol Chem 1992;267:26166-71.
12. Tuck AB, Park M, Sterns EE, Boag A, Elliott BE. Coexpression of hepatocyte growth factor and receptor (Met) in human breast carcinoma. Am J Pathol 1996; 148:225-32.
13. Lamszus K, Joseph A, Jin L, Yao Y, Chowdhury S, Fuchs A, et al. Scatter factor binds to thrombospondin and other components of the extracellular matrix. Am J Pathol 1996;149:805-19.
14. Siziopikou KP, Prioleau JE, Harris JR, Schnitt SJ. bcl-2 expression in the spectrum of preinvasive breast lesions. Cancer. In press.
15. Wang Y, Selden AC, Morgan N, Stamp GW, Hodgson HJ. Hepatocyte growth factor/scatter factor expression in human mammary epithelium. Am J Pathol 1994;144:675-82.
16. Tsarfaty I, Resau JH, Rulong S, Keydar I, Faletto DL, Vande Woude GF. The met protooncogene receptor and lumen formation. Science 1992;257:1258-61.
17. Tamura M, Arakaki N, Tsoubouchi H, Takada H, Daikuhara Y. Enhancement of human hepatocyte growth factor production by interleukin-1 alpha and -1 beta and tumor necrosis factor-alpha by fibroblasts in culture. J Biol Chem 1993;268:8140-5.
18. Seslar SP, Nakamura T, Byers SW. Regulation of fibroblast hepatocyte growth factor/scatter factor expression by human breast carcinoma cell lines and peptide growth factors. Cancer Res 1993;53:1233-8.
19. Rosen EM, Joseph A, Jin L, Rockwell S, Elias JA, Knesel J, et al. Regulation of scatter factor production via a soluble inducing factor. J Cell Biol 1994;127:225-34.
20. Moghul A, Lin L, Beedle A, Kanbour-Shakir A, DeFrances MC, Liu Y, et al. Modulation of c-MET proto-oncogene (HGF receptor) mRNA abundance by cytokines and hormones: evidence for rapid decay of the 8 kb c-MET transcript. Oncogene 1994;9:2045-52.
21. Boccaccio C, Gaudino G, Gambarotta G, Galimi F, Comoglio PM. Hepatocyte growth factor (HGF) expression is inducible and is part of the delayed-early response to HGF. J Biol Chem 1994;269:12846-51.
22. Yamashita J, Ogawa M, Beppu T. Immunoreactive hepatocyte growth factor is present in tissue extracts from human breast cancer but not in conditioned medium of human breast cancer cell lines. Res Commun Chem Pathol Pharmacol 1993;82:249-52.
23. Byers S, Park M, Sommers C, Seslar S. Breast carcinoma: a collective disorder. Breast Cancer Res Treat 1994;31:203-15.
24. Montesano R, Matsumoto K, Nakamura T, Orci L. Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor. Cell 1991;67:901-8.
25. Soriano JV, Pepper MS, Nakamura T, Orci L, Montesano R. Hepatocyte growth factor stimulates extensive development of branching duct-like structures by cloned mammary gland epithelial cells. J Cell Science 1995;108:413-30.
26. Pepper MS, Soriano JV, Menoud PA, Sappino AP, Orci L, Montesano R. Modulation of hepatocyte growth factor and c-met in the rat mammary gland during pregnancy, lactation, and involution. Exp Cell Res 1995;219:204-10.
27. Huguet EL, Smith K, Bicknell R, Harris AL. Regulation of the Wnt5a mRNA expression in human mammary epithelial cells by cell shape, confluence, and hepatocyte growth factor. J Biol Chem 1995;270:12851-6.
28. Yao Y, Jin L, Fuchs A, Joseph A, Hastings H, Goldberg ID, et al. Scatter factor protein levels in human breast cancers: clinicopathologic and biologic correlations. Am J Pathol. In press.
29. Guidi AJ, Fischer L, Harris JR, Schnitt SJ. Microvessel density and distribution in ductal carcinoma in situ of the breast. J Natl Cancer Inst 1994;86:356-61.
30. Poller DN, Roberts EC, Bell JA, Elston CW, Blarney RW, Ellis IO. p53 protein expression in mammary ductal carcinoma-in-situ: relationship to immunohistochemical expression of estrogen receptor and c-erb B-2 protein. Hum Pathol 1993;24:463-8.
31. Leal CB, Schmitt PC, Bento MJ, Maia NC, Lopes CS. Ductal carcinoma in situ of the breast. Histologic categorization and its relationship to ploidy and immunohistochemical expression of hormone receptors, p53, and c-erb B-2 protein. Cancer 1995;75:2123-31.
32. Malley PP, Vnencak-Jones CL, Dupont WD, Parl F, Manning S, Page DL. p53 mutations are confined to the comedo type ductal carcinoma in situ of the breast. Lab Invest 1994;71:67-72.
33. Bobrow LG, Happerfield LC, Gregory WM, Springall RD, Millis RR. The classification of ductal carcinoma in situ and its association with biological markers. Semin Diag Pathol 1994;11:199-207.
34. Leek RD, Kaklamanis L, Pezzella F, Gatter KC, Harris AL. Bcl-2 in normal human breast and carcinoma: association with oestrogen receptor-positive, epidermal growth factor receptor-negative tumors and in situ cancer. Br J Cancer 1994;69:135-9.
35. Hellemans P, van Dam PA, Weyler J, van Oosterom AT, Buytaert P, Van Marck E. Prognostic value of bcl-2 expression in invasive breast cancer. Br J Cancer 1995;72:354-60.
36. Bellamy CO, McDonald C, Salter DM, Chetty U, Anderson TJ. Noninvasive ductal carcinoma of the breast: the relevance of histologic categorization. Hum Pathol 1993;24:16-23.
37. Recht A, Connolly JL, Schnitt SJ, Harris JR. Therapy of in situ cancer. Hematol Oncol Clin North Am 1989;3:691-708.