Evidence for seasonal plasticity in the gonadotropin-releasing hormone (GnRH) system of the ewe: Changes in synaptic inputs onto GnRH neurons

Endocrinology

Volumn 138, Issue 3, 1997, Pages 1240-1250

  Xiong, Jin Jun ^a   Karsch, Fred J ^b   Lehman, Michael N ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL; GONADORELIN;

ANIMAL EXPERIMENT; ARTICLE; CELL ULTRASTRUCTURE; ESTRADIOL BLOOD LEVEL; FEMALE; GONADORELIN RELEASE; HORMONAL REGULATION; NEGATIVE FEEDBACK; NERVE CELL; NERVE CELL PLASTICITY; NONHUMAN; PREOPTIC AREA; PRIORITY JOURNAL; SEASONAL VARIATION; SHEEP; SYNAPTIC TRANSMISSION;

EID: 0031046169     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/endo.138.3.5000     Document Type: Article

References (69)

1. Karsch FJ, Bittman EL, Foster DL, Goodman RL, Legan SJ, Robinson JE 1984 Neuroendocrine basis of seasonal reproduction. Recent Prog Horm Res 40:185-232
2. Moore RY 1983 Organization and function of a central nervous system circadian oscillator: the suprachiasmatic hypothalamic nucleus. Fed Proc 42:2783-2789
3. Bittman EL, Karsch FJ, Hopkins JW 1983 Role of the pineal gland in ovine photoperiodism: regulation of seasonal breeding and negative feedback effects of estradiol upon LH secretion. Endocrinology 113:329-336
4. Carter DS, Goldman BD 1983 Antigonadal effects of timed melatonin infusion in pinealectomized male Djungarian hamsters (Phodopus sungorus sungorus): duration is the critical parameter. Endocrinology 113:1261-1267
5. Wayne NL, Malpaux B, Karsch FJ 1988 How does melatonin code for day length in the ewe: duration of nocturnal melatonin release or coincidence of melatonin with a light-entrained sensitive period? Biol Reprod 39:66-75
6. Twaites CJ 1965 Photoperiodic control of breeding activity in the Southdown ewe with particular reference to the effects of an equatorial light regime. J Agric Sci 65:57-64
7. Ducker MJ, Bauman JC, Temple H 1973 The effect of constant photoperiod on the expression of oestrus in the ewe. J Reprod Fertil [Suppl] 19:143-150
8. Robinson JE, Karsch FJ 1984 Refractoriness to inductive daylengths terminates the breeding season of the Suffolk ewe. Biol Reprod 31:656-663
9. Karsch FJ, Robinson JE, Woodfill CJI, Brown MB 1989 Circannual cycles of luteinizing hormone and prolactin secretion in ewes during prolonged exposure to a fixed photoperiod: evidence for an endogenous reproductive rhythm. Biol Reprod 41:1034-1046
10. Legan SJ, Karsch FJ 1983 Importance of retinal photoreceptors in the photoperiodic control of seasonal breeding in the ewe. Biol Reprod 29:316-325
11. Bittman EL, Weaver DR 1990 The distribution of melatonin binding sites in the neuroendocrine tissues of the ewe. Biol Reprod 43:986-993
12. Helliwell RJA Williams LM 1992 Melatonin binding sites in the ovine brain and pituitary: characterization during the oestrous cycle. J Neuroendocrinol 4:287-294
13. Malpaux B, Robinson JE, Wayne NL, Karsch FJ 1989 Regulation of the onset of the breeding season in the ewe: importance of long days and of an endogenous reproductive rhythm. J Endocrinol 122:269-278
14. Woodfill CJI, Robinson JE, Malpaux B, Karsch FJ 1991 Synchronization of the circannual reproductive rhythm of the ewe by discrete photoperiodic signals. Biol Reprod 45:110-121
15. Silverman AJ 1988 The gonadotropin-releasing hormone (GnRH) neuronal systems: immunocytochemistry. In: Knobil E, Neill J (eds) The Physiology of Reproduction. Raven Press, New York, pp 1283-1304
16. Fink G 1988 Gonadotropin secretion and its control. In: Knobil E, Neill J (eds) The Physiology of Reproduction. Raven Press, New York
17. Foster DL 1988 Puberty in sheep. In: Knobil E, Neill J (eds) The Physiology of Reproduction. Raven Press, New York, pp 411-452
18. Goodman RL, Bittman EB, Foster DL, Karsch FJ 1982 Alterations in the control of luteinizing hormone pulse frequency underlie the seasonal variation in estradiol negative feedback in the ewe. Biol Reprod 27:580-589
19. Karsch FJ, Dahl GE, Evans NP, Manning JM, Moenter SM, Foster DL 1993 Seasonal changes in gonadotropin-releasing hormone secretion in the ewe: alteration in response to negative feedback action of estradiol. Biol Reprod 49:1377-1383
20. Lehman MN Karsch FJ 1993 Do GnRH, tyrosine hydroxylase-, and β-endorphin-immunoreactive neurons contain estrogen receptors? A double-label immunocytochemical study in the Suffolk ewe. Endocrinology 133:887-895
21. Herbison AE, Robinson JE, Skinner DC 1992 Distribution of estrogen receptor-immunoreactive cells in the preoptic area of the ewe: co-localization with glutamic acid decarboxylase but not luteinizing hormone-releasing hormone. Neuroendocrinology 57:751-759
22. Shivers BD, Harlan RE, Morrell JI, Pfaff DW 1983 Absence of oestradiol concentration in cell nuclei of LHRH-immunoreacrive neurones. Nature 304:345-347
23. Watson RE, Langub MC, Landis JW 1992 Further evidence that most luteinizing hormone-releasing hormone neurons are not directly estrogen-responsive-simultaneous localization of luteinizing hormone-releasing hormone ad estrogen receptor immunoreactivity in the guinea pig brain. J Neuroendocrinol 4:311-317
24. Urbanski HF, Doan A, Pierce M 1991 Immunocytochemical investigation of luteinizing hormone-releasing hormone neurons in Syrian hamsters maintained under long or short days. Biol Reprod 44:687-692
25. Ronchi E, Aoki C, Krey L, Pfaff DW 1992 Immunocytochemical study of GnRH and GnRH-associated peptide in male Syrian hamsters as a function of photoperiod and gonadal alterations. Neuroendocrinology 55:134-145
26. Ronchi E, Krey L, Pfaff DW 1992 Steady state analysis of hypothalamic GnRH mRNA levels in male Syrian hamsters: influences of photoperiods and gonadal steroids. Neuroendocrinology 55:146-155
27. Karsch FJ, Lehman MN, Silverman AJ 1987 Seasonal plasticity in synaptic input to luteinizing hormone-releasing hormone (LHRH) neurons in the sheep. Neurosci Abstr 13:1527
28. Nottebohm F 1981 A brain for all seasons: cyclical anatomical changes in song control nuclei of the canary brain. Science 214:1368-1370
29. DeVoogd TJ, Nixdorf B, Nottebohm F 1985 Synaptogenesis and changes in synaptic morphology related to acquisition of a new behavior. Brain Res 329:304-308
30. Carrer HF, Aoki A 1982 Ultrastructural changes in the hypothalamic ventromedial nucleus of ovariectomized rats after estrogen treatment. Brain Res 24:221-233
31. Garcia-Segura LM, Baetens D, Naftolin F1986 Synaptic remodeling in arcuate nucleus after injection of estradiol valerate in adult female rats. Brain Res 366:131-136
32. Lehman MN, Robinson JE, Karsch FJ, Silverman AJ 1986 Immunocytochemical localization of luteinizing hormone-releasing hormone (LHRH) pathways in the sheep brain during anestrus and the mid-luteal phase of the estrous cycle. J Comp Neurol 244:19-35
33. Legan SJ, Karsch FJ, Foster DL 1977 The endocrine control of seasonal reproductive function in the ewe: a marked change in response to the negative feedback action of estradiol on luteinizing hormone secretion. Endocrinology 101:818-824
34. Caldani M, Batailler M, Thiery JC, Dubois MP 1988 LHRH-immunoreactive structures in the sheep brain. Histochemistry 88:1-11
35. Hauger RL, Karsch FJ, Foster DL 1977 A new concept for control of the estrous cycle of the ewe based on the temporal relationships between luteinizing hormone, estradiol and progesterone in peripheral serum and evidence that progesterone inhibits tonic LH secretion. Endocrinology 101:807-817
36. Niswender GD, Reichert Jr LE, Midgley Jr AR, Nalbandov AV 1969 Radioimmunoassay for bovine and ovine luteinizing hormone. Endocrinology 84:1166-1173
37. Itoh K, Konishi A, Nomura S, Mizuno N, Nakamura Y, Sugimoto T 1979 Application of coupled oxidation reaction to electron microscopic demonstration of horseradish peroxidase: cobalt-glucose oxidase method. Cell Tissue Res 198:381-39
38. Langford LA, Coggeshall RE 1980 The use of potassium ferricyanide in neural fixation. Anat Rec 197:297-303
39. Venable JH, Coggeshall RA 1965 A simplified lead citrate stain for use in electron microscopy. J Cell Biol 25:405-408
40. Zhu PC, Thurelson-Klein A, Klein RL 1986 Exocytosis from large dense cored vesicles outside the active synaptic zones of terminals within the trigeminal subnucleus caudalis: a possible mechanism for neuropeptide release. Neuroscience 19:43-54
41. Lehman MN, Karsch FJ, Robinson JE, Silverman AJ 1988 Ultrastructure and synaptic organization of luteinizing hormone-releasing hormone (LHRH) neurons in the anestrous ewe. J Comp Neurol 273:447-458
42. Olmos G, Naftolin F, Tranque O, Garcia-Segura LM 1989 Synaptic remodeling in the rat arcuate nucleus during the estrus cycle. Neuroscience 32:663-667
43. McEwen BS, Woolley CS 1994 Estradiol and progesterone regulate neuronal structure and synaptic connectivity in adult as well as developing brain. Exp Gerontol 29:431-436
44. Nottebohm F, Nottebohm ME, Crane L 1986 Developmental and seasonal changes in canary song and their relationship to changes in the anatomy of song-control nuclei. Behav Neural Biol 46:445-471
45. Brown SD, Johnson F, Bottjer SW 1993 Neurogenesis in adult canary telencephalon is independent of gonadal hormone levels. J Neurosci 13:2024-2032
46. Goldsmith AR Nichols TJ 1984 Thyroidectomy prevents the development of photorefractoriness and the associated rise in plasma prolactin in starlings. Gen Comp Endocrinol 54:256-263
47. Moenter SM, Woodfill CJI, Karsch FJ 1991 Role of the thyroid gland in seasonal reproduction: thyroidectomy blocks seasonal suppression of reproductive neuroendocrine activity in ewes. Endocrinology 128:1337-1344
48. Webster JR, Moenter SM, Barrell GK, Lehman MN, Karsch FJ 1991 Role of the thyroid gland in seasonal reproduction. III. Thyroidectomy blocks seasonal suppression of gonadotropin-releasing hormone secretion in sheep. Endocrinology 129:1635-1643
49. Webster JR, Moenter SM, Woodfill CJI, Karsch FJ 1991 Role of the thyroid gland in seasonal reproduction: II. Thyroxine allows a season-specific suppression of gonadotropin secretion in sheep. Endocrinology 129:176-183
50. Slotkin TA, Slepetis RJ 1984 Obligatory role of thyroid hormones in development of peripheral sympathetic and central nervous system catecholaminergic neurons: effects of propylthiouracil-induced hypothyroidism on transmitter levels, turnover and release. J Pharmacol Exp Ther 230:53-61
51. Granholm A-Ch 1985 Effects of thyroid hormone deficiency on glial constituents in developing cerebellum of the rat. Exp Brain Res 59:451-456
52. Parry DM, Goldsmith AR 1993 Ultrastructural evidence for changes in synaptic input to the hypothalamic luteinizing hormone-releasing hormone neurons in photosensitive and photorefractory starlings. J Neuroendocrinol 5:387-395
53. Halasz B, Kiss J, Molnar J 1989 Regulation of the gonadotropin-releasing hormone (GnRH) neuronal system: morphological aspects. J Steroid Biochem 33:663-668
54. Uchizono K 1965 Characteristics of excitatory and inhibitory synapses in the central nervous system of the cat. Nature 207:642
55. Matus AI, Dennison ME 1971 Autoradiographic localisation of tritiated glycine at "flat-vesicle" synapses in the spinal cord. Brain Res 32:195-197
56. Decavel C, Van Den Pol AN 1990 GABA: a dominant neurotransmitter in the hypothalamus. J Comp Neurol 302:1019-1037
57. Reardon TF, Robinson TJ 1961 Seasonal variation in the reactivity to oestrogen of the ovariectomized ewe. Austr J Agric Res 12:320-326
58. Goodman RL, Legan SJ, Ryan KD, Foster DL, Karsch FJ 1981 Importance in variations in behavioural and feedback actions of oestradiol to the control of seasonal breeding in the ewe. J Endocrinol 89:229-240
59. Sakuma Y, Pfaff DW 1983 Modulation of the lordosis reflex of female rats by LHRH, its antiserum and analogs in the mesencephalic central gray. Neuroendocrinology 36:218-224
60. Reier PJ, Eng LF, Jakeman L 1989 Reactive astrocyte and axonal outgrowth in the injured CNS: is gliosis really an impediment to regeneration? In: Seil FS (ed) Neural Regeneration and Transplantation. Liss, New York, pp 183-209
61. Hatton GI, Perlmutter LS, Salm AK, Tweedle CD 1984 Dynamic neuronalglial interactions in hypothalamus and pituitary: implications for the control of hormone synthesis and release. Peptides 5:121-138
62. Theodosis DT, Poulain DA 1987 Oxytocin-secreting neurones: a physiological model for structural plasticity in the adult mammalian brain. Trends Neurosci 10:426-430
63. Hatton GI 1988 Cellular reorganization in neuroendocrine secretion. Curr Top Neuroendocrinol 9:1-27
64. Witkin J, Ferin M, Popilskis SJ, Silverman AJ 1991 Effects of gonadal steroids on the ultrastructure of GnRH neurons in the rhesus monkey: synaptic input and glial apposition. Endocrinology 129:1083-1092
65. Xiong J-J, Moenter SM, Caraty A, Lehman MN 1990 Ultrastructural comparison of GnRH axons and terminals in the median eminence of the ewe: changes during the periovulatory period. Biol Reprod [Suppl 1] 42:102
66. King JC, Rubin BS 1994 Dynamic changes in LHRH neurovascular terminals with various endocrine conditions in adults. Horm Behav 28:349-356
67. Witkin J 1987 Aging changes in synaptology of luteinizing hormone-releasing hormone neurons in male rat preoptic area. Neuroscience 22:1003-1013
68. Barrell GK, Moenter SM, Carat A, Karsch FJ 1992 Seasonal changes of gonadotropin-releasing hormone secretion in the ewe. Biol Reprod 46:1130-1135
69. Clarke IJ 1988 Gonadotrophin releasing hormone (GnRH) secretion in anoestrous ewes and the induction of GnRH surges by oestrogen. J Endocrinol 117:355-360