Interferon maintenance therapy for small cell lung cancer: Improvement in long-term survival

Journal of Interferon and Cytokine Research

Volumn 17, Issue 2, 1997, Pages 103-105

  Mattson, K ^a,d   Niiranen, A ^a   Ruotsalainen, T ^a   Maasilta, P ^a   Halme, M ^a   Pyrhonen S ^b   Kajanti, M ^b   Mantyla M ^b   Tamminen, K ^a   Jekunen, A ^b   Sarna, S ^b   Cantell, K ^c  

^a Department of Orthopedics   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

^c NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^d HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; CISPLATIN; CYCLOPHOSPHAMIDE; DOXORUBICIN; ETOPOSIDE; VINCRISTINE;

ADULT; AGED; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER IMMUNOTHERAPY; CANCER RADIOTHERAPY; CANCER SURVIVAL; CLINICAL TRIAL; DOSE RESPONSE; DRUG EFFICACY; FEMALE; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; LUNG SMALL CELL CANCER; MAINTENANCE THERAPY; MAJOR CLINICAL STUDY; MALE; ORAL DRUG ADMINISTRATION; PHASE 3 CLINICAL TRIAL; PRIORITY JOURNAL; SURVIVAL TIME; TREATMENT OUTCOME;

EID: 0031045897     PISSN: 10799907     EISSN: None     Source Type: Journal    
DOI: 10.1089/jir.1997.17.103     Document Type: Article

References (5)

1. MATTSON, K., NIIRANEN, A., PYRHÖNEN, S., HOLSTI, L.R., HOLSTI, P., KUMPULAINEN, E., and CANTELL, K. (1992). Natural Interferon alpha as maintenance therapy for small cell lung cancer. Eur. J. Cancer 28A, 1387-1391.
2. KOHNE-WUMPNER, C.H., KOSCHEL, G., PAWEL, J., et al. (1992). Carboplatin, etoposide, vincristine chemotherapy plus radiotherapy in limited disease small cell lung cancer, followed by maintenance with interferon-alpha 2B versus observation. Ann. Oncol. 3 (Suppl. 5):40.
3. TUMMARELLO, D., GRAZIANO, F., MARI, D., et al. (1994). Small cell lung cancer: A randomized trial of cyclophosphamide, adriamycin, vincristine plus etoposide (CAV-E) or teniposide (CAV-T) as induction treatment, followed in complete responders by alfa-interferon or no treatment, as maintenance therapy. Anticancer Res. 14, 2221-2228.
4. KELLY, K., CROWLEY, J.J., BUNN, P.A., et al. (1995). Role of recombinant interferon alfa-2a maintenance in patients with limited stage small cell lung cancer responding to concurrent chemoradia-tion: A Southwest Oncology Group Study. J. Clin. Oncol. 13, 2924-2930.
5. MATTSON, K., MAASILTA, P., HALME, M., NIIRANEN, A., PYRHÖNEN, S., RISKA, H., CANTELL, K., and ENLUND, J. (1993). Chemotherapy plus alpha-interferon in the treatment of small cell lung cancer. A randomised phase III study. Am. Rev. Respir. Dis. 147, A748.