TAP polymorphisms in Swedish myasthenia gravis patients

Tissue Antigens

Volumn 49, Issue 2, 1997, Pages 176-179

  Hjelmstrom P ^a   Giscombe, R ^a   Lefvert, A K ^a   Pirskanen, R ^b   Kockum, I ^a   Landin Olsson, M ^c   Sanjeevi, C B ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b STOCKHOLM SÖDER HOSPITAL   (Sweden)

^c LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

HLA DQ2; HLA DR3; Myasthenia gravis; Stratification analysis; TAP

Indexed keywords

HLA DQ ANTIGEN; HLA DR3 ANTIGEN;

ALLELE; ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; GENE LINKAGE DISEQUILIBRIUM; HUMAN; MAJOR CLINICAL STUDY; MYASTHENIA GRAVIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SWEDEN;

EID: 0031045718     PISSN: 00012815     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1399-0039.1997.tb02733.x     Document Type: Article

References (17)

1. Pirskanen R Tiilikainen A, Hokkanen E. Histocompatibility (HL-A) antigens associated with myasthenia gravis. Ann. Clin Rev 1972: 4: 304-306.
2. Degli-Esposti MA, Andreas A, Christiansen FT, Schalke B, Albert E, Dawkins, RL. An approach to the localization of the susceptibility genes for general myasthenia gravis by mapping recombinant ancestral haplotypes. Immunogenetics 1992: 35: 355-364.
3. Vieira ML, Caillat-Zucman S, Gajdos P, Cohen-Kaminsky S, Casteur A, Bach J-F. Identification by genomic typing of non-DR3 HLA class II genes associated with myasthenia gravis. J Neuroimmunol 1993: 47: 115-122.
4. Ratanachaiyavong S, Fleming D, Janer M et al. HLA-DP1 polymorphisms in patients with hyperthyroid Graves' disease and early onset myasthenia gravis. Autoimmunity 1994: 17: 99-104.
5. Hjelmström P, Giscombe R, Lefvert AK et al. Different HLA-DQ are positively and negatively associated in Swedish patients with myasthenia gravis. Autoimmunity 1995: 22: 59-65.
6. Compston DAS, Vincent A, Newsom-Davis J, Batchelor JR. Clinical, pathological, HLA antigen and immunological evidence for disease heterogeneity in myasthenia gravis. Brain 1980: 103: 579-601.
7. Spurkland A, Gilhus NE, Rønningen KS, Aarli JA, Vartdal F. Myasthenia gravis patients with thymus hyperplasia and myasthenia gravis patients with thymoma display different HLA associations. Tissue Antigens 1991: 37: 90-93.
8. Hjelmström P, Giscombe, R, Lefvert, AK et al. Domains of polymorphic amino acids in the HLA-DQ molecule are associated with disease heterogeCneity in myasthenia gravis. J Neuroimmunol 65: 125-131.
9. Begovich AB, McClure GR, Suraj VC et al. Polymorphism, recombination, and linkage disequilibrium within the HLA class II region. J Immunol 1992: 148: 249-258.
10. Olerup O, Zetterquist H. HLA-DR typing by PCR amplification with sequence-specific primers (PCR-SSP) in 2 hours: an alternative to serological DR typing in clinical practice including donor-recipient matching in cadaveric transplantation. Tissue Antigens 1992: 39: 225-235.
11. Powis SH, Tonks S, Mockridge I, Kelly AP, Bodmer JG, Trowsdale J. Alleles and haplotypes of the MHC-encoded ABC transporters TAP1 and TAP2. Immunogenetics 1993: 37: 373-380.
12. Svejgaard A, Ryder L. HLA and disease associations: Detecting the strongest association. Tissue Antigens 1994: 43: 18-27.
13. Cullen M, Erlich H, Klitz W, Carrington M. Molecular mapping of a recombination hotspot located in the second intron of the human TAP2 locus. Am J Hum Genet 1995: 56: 1350-1358.
14. Klitz W, Stephens JC, Grote M, Carrington M. Discordant patterns of linkage disequilibrium of the peptide-transporter loci within the HLA class II region. Am J Hum Genet 1995: 57: 1436-1444.
15. Murphy J, Murphy SF. Myathenia gravis in identical twins. Neurology 1986: 36: 78-80.
16. Heckmann JM, Morrison KE, Emeryk-Szajewska B et al. Human muscle acetylcholine receptor alpha subunit gene (CHRNA1) association with autoimmune myasthenia gravis in black, mixed-ancestry and Caucasian subjects. J Autoimmun 1996: 9: 175-180.
17. Demaine A, Willcox N, Janer M, Welsh K, Newsom-Davis J. Immunoglobulin heavy chain gene associations in myasthenia gravis: new evidence for disease heterogeneity. J Neurol 1992: 239: 53-56.