G protein-dependent inhibition of L-type Ca2+ currents by acetylcholine in mouse pancreatic B-cells

Journal of Physiology

Volumn 499, Issue 1, 1997, Pages 65-76

  Gilon, Patrick ^a,b,c   Yakel, Jerrel ^b   Gromada, Jesper ^a   Zhu, Yu ^b   Henquin, Jean Claude ^c   Rorsman, Patrik ^a  

^a NOVO NORDISK A S   (Denmark)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c UNIVERSITY OF LOUVAIN MEDICAL SCHOOL   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 [2 (TRIFLUOROMETHYL)PHENYL] 3 PYRIDINECARBOXYLIC ACID METHYL ESTER; ACETYLCHOLINE; ATROPINE; BARIUM ION; CALCIUM ION; CHOLERA TOXIN; CONOTOXIN; EGTAZIC ACID; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); GUANOSINE DERIVATIVE; MUSCARINIC RECEPTOR; NIFEDIPINE; PERTUSSIS TOXIN; TOXIN;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM CURRENT; CALCIUM MOBILIZATION; CELL MEMBRANE POTENTIAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PATCH CLAMP; PRIORITY JOURNAL;

EID: 0031045627     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.1997.sp021911     Document Type: Article

References (39)

1. AHRÉN, B., TABORSKY, G. J. & PORTE, D. (1986). Neuropeptidergic versus cholinergic and adrenergic regulation of islet hormone secretion. Diabetologia 29, 827-836.
2. ÄMMÄLÄ, C., BERGGREN, P. O., BOKVIST, K. & RORSMAN, P. (1992). Inhibition of L-type calcium channels by internal GTP [γS] in mouse pancreatic β cells. Pflügers Archiv 420, 72-77.
3. ÄMMÄLÄ, C., ELIASSON, L., BOKVIST, K., BERGGREN, P.-O., HONKANEN, R. E., SJÖHOLM, Å. & RORSMAN, P. (1994). Activation of protein kinases and inhibition of protein phosphatases play a central role in the regulation of exocytosis in mouse pancreatic β cells. Proceedings of the National Academy of Sciences of the USA 91, 4343-4347.
4. ASHCROFT, F. M. & RORSMAN, P. (1989). Electrophysiology of the pancreatic β-cell. Progress in Biophysics and Molecular Biology 54, 87-143.
5. 2+ efflux. Biochemical and Biophysical Research Communications 165, 416-421.
6. 2+ current and M current in rat sympathetic neurons. Proceedings of the National Academy of Sciences of the USA 89, 9544-9548.
7. BIRNBAUMER, L., ABRAMOWITZ, J. & BROWN, A. M. (1990). Receptor-effector-coupling by G-proteins. Biochimica et Biophysica Acta 1031, 163-224.
8. 2+ channels and insulin-containing secretory granules and its significance for the initiation of exocytosis in mouse pancreatic B-cells. EMBO Journal 14, 50-57.
9. 3 muscarinic receptors. American Journal of Physiology 268, E336-342.
10. DOLPHIN, A. C. (1991). Regulation of calcium channel activity by GTP binding proteins and second messengers. Biochimica et Biophysica Acta 1091, 68-80.
11. DOLPHIN, A. C., MCGUIRK, S. M. & SCOTT, R. H. (1989). An investigation into the mechanisms of inhibition of calcium channel currents in cultured sensory neurones of the rat by guanine nucleotides analogues and (-)-baclofen. British Journal of Pharmacology 97, 263-273.
12. GAGERMAN, E., IDAHL, L. A., MEISSNER, H. P. & TÄLJEDAL, I. B. (1978). Insulin release, cGMP, cAMP, and membrane potential in acetylcholine-stimulated islets. American Journal of Physiology 236, E493-500.
13. GAO, Z. Y., GILON, P. & HENQUIN, J. C. (1994). The role of protein kinase C in signal transduction through vasopressin and acetylcholine receptors in pancreatic B-cells from normal mouse. Endocrinology 135, 191-199.
14. GARCIA, M. C., HERMANS, M. & HENQUIN, J. C. (1988). Glucose-, calcium- and concentration-dependence of acetylcholine stimulation of insulin release and ionic fluxes in mouse islets. Biochemical Journal 254, 211-218.
15. 2+ in the electrically excitable pancreatic B-cell. Biochemical Journal 311, 259-267.
16. HENQUIN, J. C., GARCIA, M. C., BOZEM, M., HERMANS, M. P. & NENQUIN, M. (1988). Muscarinic control of pancreatic B cell function involves sodium-dependent depolarization and calcium influx. Endocrinology 122, 2134-2142.
17. HENQUIN, J. C. & NENQUIN, M. (1988). The muscarinic receptor subtype in mouse pancreatic B-cells. FEBS Letters 236, 89-92.
18. HILLE, B. (1992). G-protein-coupled mechanisms and nervous signaling. Neuron 9, 187-195.
19. HILLE, B. (1994). Modulation of ion-channel function by G-protein-coupled receptors. Trends in Neurosciences 17, 531-536.
20. 2+ current in the RINm5F cell line. Proceedings of the National Academy of Sciences of the USA 88, 8744-8748.
21. HOPKINS, W. F., SATIN, L. S. & COOK, D. L. (1991). Inactivation kinetics and pharmacology distinguish two calcium currents in mouse pancreatic B-cells. Journal of Membrane Biology 119, 229-239.
22. 2+ channels in the beta cell. Journal of Biological Chemistry 266, 837-843.
23. HULME, E. C., CURTIS, C. A. M., PAGE, K. M. & JONES, P. G. (1993). Agonist activation of muscarinic acetylcholine receptors. Cellular Signalling 5, 687-694.
24. JONES, S. V. P. (1993). Muscarinic receptors subtypes: modulation of ion channels. Life Sciences 52, 457-464.
25. KEAHEY, H. H., BOYD, A. E. & KUNZE, D. L. (1989). Catecholamine modulation of calcium currents in clonal pancreatic β-cells. American Journal of Physiology 257, C1171-1176.
26. KRAMER, R. H., KACZMAREK, L. K. & LEVITAN, E. S. (1991). Neuropeptide inhibition of voltage-gated calcium channels mediated by mobilization of intracellular calcium. Neuron 6, 557-563.
27. 2+ channels in rat insulinoma RINm5F cells by ω-agatoxin IVA and ω-conotoxin MVIIC. Pflügers Archiv 429, 762-771.
28. MATHIE, A., BERNHEIM, L. & HILLE, B. (1992). Inhibition of N- and L-type calcium channels by muscarinic receptor activation in rat sympathetic neurons. Neuron 8, 907-914.
29. 3 cells. Molecular Endocrinology 5, 995-1002.
30. PLANT, T. D. (1988). Properties and calcium-dependent inactivation of calcium currents in cultured mouse pancreatic B-cells. Journal of Physiology 404, 731-747.
31. RAE, J., COOPER, K., GATES, P. & WATSKY, M. (1991). Low access resistance perforated patch recordings using amphotericin B. Journal of Neuorscience Methods 37, 15-26.
32. RASMUSSEN, H., ZAWALICH, H., GANESAN, S., CALLE, R. & ZAWALICH, W. S. (1990). Physiology and pathophysiology of insulin secretion. Diabetes Care 13, 655-666.
33. RENSTRÖM, E., DING, W.-G., BOKVIST, K. & RORSMAN, P. (1996). Neurotransmitter-induced inhibition of exocytosis in insulin-secreting β cells by activation of calcineurin. Neuron 17, 513-522.
34. RORSMAN, P., ASHCROFT, F. M. & TRUBE, G. (1988). Single Ca channel currents in mouse pancreatic B-cells. Pflügers Archiv 412, 597-603.
35. SÁNCHEZ-ANDRÉS, J. V., RIPOLL, C. & SORIA, B. (1988). Evidence that muscarinic potentiation of insulin release is initiated by an early transient calcium entry. FEBS Letters 231, 143-147.
36. SMITH, P. A., ASHCROFT, F. M. & FEWTRELL, C. M. S. (1992). Permeation and gating properties of the L-type calcium channel in mouse pancreatic β-cell. Journal of General Physiology 101, 767-797.
37. 2+) channel currents in the insulin-secreting cell line RINm5F. Quarterly Journal of Experimental Physiology 74, 367-370.
38. VERSPOHL, E. J., TACKE, R., MUTSCHLER, E. & LAMBRECHT, G. (1990). Muscarinic receptor subtypes in rat pancreatic islets: binding and functional studies. European Journal of Pharmacology 178, 303-311.
39. 2+ origin. Journal of Physiology 488, 13-24.