Analysis of human T cell responses to group A streptococci using fractionated Streptococcus pyogenes proteins

FEMS Immunology and Medical Microbiology

Volumn 17, Issue 3, 1997, Pages 161-170

  Degnan, Beverley A ^a   Kehoe, Michael A ^a   Goodacre, John A ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

antigen; electroelution; Streptococcus pyogenes; superantigen; T lymphocyte

Indexed keywords

BACTERIAL ANTIGEN; BACTERIAL PROTEIN; EXOTOXIN; SUPERANTIGEN;

ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; STREPTOCOCCUS GROUP A; STREPTOCOCCUS PYOGENES; T LYMPHOCYTE ACTIVATION;

ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; CELLS, CULTURED; HUMANS; STREPTOCOCCUS PYOGENES; T-LYMPHOCYTES;

EID: 0031044762     PISSN: 09288244     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-8244(97)00004-7     Document Type: Article

References (37)

1. Michie, C., Scott, A., Cheesbrough, J., Beverley, P. and Pasvol, G. (1994) Streptococcal toxic shock-like syndrome: evidence of superantigen activity and its effects on T lymphocyte subsets in vivo. Clin. Exp. Immunol. 98, 140-144.
2. Stevens, D.L., Tanner, M.H., Winship, J., Swarts, R., Ries, K.M., Schlievert, P.M. and Kaplan, E. (1989) Severe group A streptococcal infections associated with toxic shock-like syndrome and scarlet fever toxin A. N. Engl. J. Med. 321, 1-7.
3. Bisno, A.L. (1991) Group A streptococcal infections and acute rheumatic fever. N. Engl. J. Med. 325, 783-793.
4. Bisno, A.L. (1993) Acute rheumatic fever: A present-day perspective. Medicine 72, 278-283.
5. Stollerman, G.H. (1991) Rheumatogenic streptococci and autoimmunity. Clin. Immunol. Immunopathol. 61, 131-142.
6. Arnold, M.H. and Tyndall, A. (1989) Poststreptococcal reactive arthritis. Ann. Rheum. Dis. 48, 686-688.
7. Livneh, A., Sharma, K., Sewell, K.L. and Keiser, H.D. (1991) Multisystem disease in post-streptococcal arthritis. Ann. Rheum. Dis. 50, 328-329.
8. Robinson, J.H. and Kehoe, M.A. (1992) Group A streptococcal M proteins: virulence factors and protective antigens. Immunol. Today 13, 362-367.
9. Fischetti, V.A. (1989) Streptococcal M protein: molecular design and biological behaviour. Clin. Microbiol. Rev. 2, 285-314.
10. Baird, R.W., Bronze, M.S., Kraus, W., Hill, H.R., Veasey, L.G., and Dale, J.B. (1991) Epitopes of group A streptococcal M protein shared with antignes of articular cartilage and synovium. J. Immunol. 146, 3132-3137.
11. Bronze, M.S. and Dale, J.B. (1993) Epitopes of streptococcal M proteins that evoke antibodies that cross-react with human brain. J. Immunol. 151, 2820-2828.
12. Feldmann, M., Brennan, F.M., and Maini, R.N. (1996) Rheumatoid arthritis. Cell 85, 307-310.
13. Tisch, R., and McDevitt, H. (1996) Insulin-dependent diabetes mellitus. Cell 85, 291-297.
14. Fleischer, B., Schmidt, K-H., Gerlach, D. and Kohler, W. (1992) Separation of T-cell stimulating activity from streptococcal M protein. Infect. Immun. 60, 1767-1770.
15. Schmidt, K.H., Gerlach, D., Wollweber, L., Reichardt, W., Mann, K., Ozegowski, J.H. and Fleischer, B. (1995) Mitogenicity of M5 protein extracted from Streptococcus pyogenes cells is due to streptococcal pyrogenic exotoxin C and mitogenic factor MF. Infect. Immun. 63, 4569-4575.
16. Braun, M.A., Gerlach, D., Hartwig, U.F., Ozegowski, J-H., Romagne, F., Carrel, S., Kohler, W. and Fleischer, B. (1993) Stimulation of human T-cells by streptococcal 'superantigen' erythrogenic toxins (Scarlet Fever Toxins). J. Immunol. 150, 2457-2466.
17. Ozegowski, J.H., Knoll, H., Gerlach, D. and Kohler, W. (1984) Investigation of erythrogenic toxin C produced by Streptococcus pyogenes. Zentralbl. Bakteriol. Mikrobiol. Hyg. Ser. A 257, 38-50.
18. McMillian, R.A., Bloomster, T.A., Saeed, A.M., Henderson, K.L., Zinn, N.E., Abernathy, R., Watson, D.W. and Greenberg, R.N. (1987) Characterization of a fourth streptococcal pyrogenic exotoxin (SPED). FEMS Microbiol. Lett. 44, 317-322.
19. Norrby-Teglund, A., Newton, D., Kotb, M., Holm, S.E. and Norgren, M. (1994) Superantigenic properties of the group A streptococcal exotoxin SpeF (MF). Infect. Immun. 62, 5227-5233.
20. Yutsudo, T., Okumura, K., Iwasaki, M., Hara, A., Kamitani, S., Minamide, W., Igarashi, H., and Hinuma, Y. (1994) The gene encoding a new mitogenic factor in a Streptococcus pyogenes strain is distributed only in group A streptococci. Infect. Immun. 62, 4000-4004.
21. Yutsudo, T., Murai, H., Gonzalez, J., Takao, T., Shimonishi, Y., Takeda, Y., Igarashi, H. and Hinuma, Y. (1992) A new type of mitogenic factor produced by Streptococcus pyogenes. FEBS Lett. 1, 30-34.
22. Itoh, T., Satoh, H., Isono, N., Rikiishi, H. and Kumagai, K. (1992) Mechanism of stimulation of T cells by Streptococcus pyogenes: isolation of a major mitogenic factor, cytoplasmic membrane-associated protein. Infect. Immun. 60, 3128-3135.
23. Sato, H., Itoh, T., Rikiishi, H. and Kumagai, K. (1994) Cytoplasmic membrane-associated protein (CAP) isolated from Streptococcus pyogenes: a new bacterial superantigen. Microbiol. Immunol. 38, 139-147.
24. Mollick, J.A., Miller, G.G., Musser, J.M., Cook, R.G., Grossman, D. and Rich, R.R. (1993) A novel superantigen isolated from pathogenic strains of Streptococcus pyogenes with aminoterminal homology to staphylococcal enterotoxins B and C. J. Clin. Invest. 92, 710-719.
25. Gulle, H., Schoel, B. and Kaufmann, S.H.E. (1990) Direct blotting with viable cells of protein mixtures separated by two-dimensional gel electrophoresis. J. Immun. Methods 133, 253-261.
26. Daugelat, S., Gulle, H., Schoel, B. and Kaufmann, S.H.E. (1992) Secreted antigens of Mycobacterium tuberculosis: characterization with T lymphocytes from patients and contacts after two-dimensional separation. J. Infect. Dis. 166, 186-190.
27. Daugelat, S., Ladel, C.H. and Kaufmann, S.H.E. (1995) Influence of mouse strain and vaccine viability on T-cell responses induced by Mycobacterium bovis Bacillus Calmette-Guerin. Infect. Immun. 63, 2033-2040.
28. Stevens, M.G., Olsen, S.C. and Cheville, N.F. (1994) Lymphocyte proliferation in response to immunodominant antigens of Brucella abortus 2308 and RB51 in strain 2308-infected cattle. Infect. Immun. 62, 4616-4649.
29. Stevens, M.G., Olsen, S.C. and Cheville, N.F. (1995) Comparative analysis of immune responses in cattle vaccinated with Brucella abortus strain 19 or strain RB51. Vet. Immunol. Immunopath. 44, 223-235.
30. Stevens, M.G., Olsen, S.C. and Cheville, N.F. (1996) Lymphocyte proliferation in response to Brucella abortus RB51 and 2308 proteins in RB51-vaccinated or 2308-infected cattle. Infect. Immun. 64, 1007-1010.
31. Laemmli, U.K. (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
32. Hochstrasser, D.F., Patchornik, A. and Merril, C.R. (1989) Development of polyacrylamide gels that improve the separation of proteins and their detection by silver staining. Anal. Biochem. 173, 412-423.
33. Schoel, B., Gulle, H. and Kaufmann, S.H.E. (1992) Heterogeneity of the repertoire of T cells of tuberculosis patients and healthy contacts to Mycobacterium tuberculosis antigens separated by high-resolution techniques. Infect. Immun. 60, 1717-1720.
34. Fleischer, B., Gerlach, D., Fuhrmann, A. and Schmidt, K-H. (1995) Superantigens and pseudoantigens of gram-positive cocci. Med. Microbiol. Immunol. 184, 1-8.
35. Herman, A., Kappler, J.W., Marrack, P. and Pullen, A.M. (1991) Superantigens: mechanism of T-cell stimulation and role in immune responses. Annu. Rev. Immunol. 9, 745-772.
36. Kotzin, B.L., Leung, D.Y.M., Kappler, J. and Marrack, P. (1993) Superantigens and their potential role in human disease. Adv. Immunol. 54, 99-117.
37. Boesen, H., Jensen, B.N., Wilcke, T. and Andersen, P. (1995) Human T-cell responses to secreted antigen fractions of Mycobacterium tuberculosis. Infect. Immun. 63, 1491-1497.