Determination of genotoxicity of the metabolites of the pesticides Guthion, Sencor, Lorox, Reglone, Daconil and Admire by 32P-postlabeling

Molecular and Cellular Biochemistry

Volumn 169, Issue 1-2, 1997, Pages 177-184

  Shah, Rashmi G ^a   Lagueux, Jean ^a   Kapur, Sanjay ^a   Levallois, Patrick ^b,c   Ayotte, Pierre ^b,c   Tremblay, Martine ^b   Zee, John ^c   Poirier, Guy G ^a  

^a LAVAL UNIVERSITY   (Canada)

^b Ctr de S Pub de Quebec   (Canada)

^c UNIVERSITÉ LAVAL   (Canada)

Author keywords

32P postlabeling; Butanol extraction; DNA adducts; Nuclease P1; Pesticides

Indexed keywords

AZINPHOS METHYL; BUTANOL; CHLOROTHALONIL; DIQUAT; DRUG METABOLITE; METRIBUZIN; NUCLEASE; PESTICIDE; PHOSPHORUS 32; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

ANIMAL CELL; ARTICLE; AUTORADIOGRAPHY; CONTROLLED STUDY; DNA ADDUCT; GENOTOXICITY; ISOTOPE LABELING; NONHUMAN;

ADENOSINE TRIPHOSPHATE; ANIMALS; ASPERGILLUS NUCLEASE S1; BUTANOLS; CATTLE; CHROMATOGRAPHY, THIN LAYER; DNA; DNA ADDUCTS; MICROSOMES, LIVER; PESTICIDES; PHOSPHORUS RADIOISOTOPES; RATS; THYMUS GLAND;

EID: 0031044357     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1006861621031     Document Type: Article

References (41)

1. Keith G, Dirheimer G: Postlabeling: a sensitive method for studying DNA adducts and their role in carcinogenesis. Curr Opin Biotechnol 6: 3-11, 1995
2. Miller EC: Some current perspective on chemical carcinogenesis in human and experimental animals. Cancer Research 38: 1479-1496, 1978
3. Minakata K, Suzuki O, Oh-ishi S, Hayashi I, Saito S, Harada N: Diquat increases cysteine proteinase inhibitors greatly in rat plasma and tissues. Arch Toxicol 69: 318-321, 1995
4. Awad JA, Burk RF, Roberts LJ II: Effect of selenium deficiency and glutathione-modulating agents on diquat toxicity and lipid peroxidation in rats. J Pharmacol Exp Ther 270: 858-864, 1994
5. McCurdy SA, Hansen ME, Weisskopf CP, Lopez RL, Schneider F, Spencer J, Sanborn JR, Krieger RI, Wilson BW, Goldsmith DF, et al.: Assessment of azinphosmethyl exposure in California peach harvest workers. Arch Environ Health 49: 289-296, 1994
6. Roloff BD, Belluck DA, Meisner LF: Cytogenetic studies of herbicide interactions in vitro and in vivo using atrazine and linuron. Arch Environ Contain Toxicol 22: 267-271, 1992
7. Ameno K, Fuke C, Shirakawa Y, Ogura S, Ameno S, Kiriu T, Kinoshita H, Ijiri I: Different distribution of paraquat and diquat in human poisoning cases after ingestion of a combined herbicide. Arch Toxicol 68: 134-137, 1994
8. 32P-labeling test for DNA damage. Proc Natl Acad Sci USA 78: 6126-6129, 1981
9. 32P-postlabeling test for structurally diverse DNA adducts. Carcinogenesis 7: 1543-1551, 1986
10. 32P-postlabeling analysis of aromatic carcinogen: DNA adducts. Cancer Research 45: 5656-5662, 1985
11. Bianchi L, Zannoli A, Pizzala R, Stivala L A, Chiesara E: Genotoxicity assay of five pesticides and their mixtures in Saccharomyces cerevisiae D7. Mutat Res 321: 203-211, 1994
12. Gilot-Delhalle J, Collozi A, Moutschen J, Moutschen-Dahmen M: Mutagenicity of some organophosphorus compounds at the ade6 locus of Schizosaccharomyces pombe. Mutation Research 117: 139-148, 1983
13. Marinovich M, Guizzetti M, Galli CL: Mixtures of benomyl, pirimiphosmethyl, dimethoate, diazinon and azinphos-methyl affect protein synthesis in HL-60 cells differently. Toxicology 94: 173-185, 1994
14. Cook JC, Mullin LS, Frame SR, Biegel LB: Investigation of a mechanism for Leydig cell tumorigenesis by linuron in rats. Toxicol Appl Pharmacol 119: 195-204, 1993
15. Scassellati Sforzolini G, Moretti M, Villarini M, Monarca S, Fatigoni C, Pasquini R: In vivo studies on enzymatic induction activity of Linuron. J Environ Pathol Toxicol Oncol 13: 11-17, 1994
16. Anfossi P, Roncada P, Stracciari GL, Montana M, Pasqualucci C, Montesissa C: Toxicokinetics and metabolism of in vivo and in vitro studies. Xenobiotica 23: 1113-1123, 1993
17. Anderson KJ, Leighty EG, Takahashi MT: Evaluation of herbicides for possible mutagenic properties. J Agric Food Chem 20: 649-656, 1972
18. Benigni R, Bignami M, Carer A, Conti G, Conti L, Crebelli R, Dogliotti E, Gualandi G, Novelleto A, Ortali VA: Mutational studies with diquat and paraquat in vitro. Mutat Res 68: 183-193, 1979
19. Levin DE, Hollstein M, Christman MF, Scwiers EA, Ames B: A new Salmonella tester strain (TA 102) with AT base pairs at the site of mutation detects oxidative mutagens. Proc Natl Acad Sci USA 79: 7445-7449, 1982
20. Gallagher EP, Buetler TM, Stapleton PL, Wang C, Stahl DL, Eaton DL: The effects of diquat and ciprofibrate on mRNA expression and catalytic activities of hepatic xenobiotic metabolizing and antioxidant enzymes in rat liver. Toxicol Appl Pharmacol 134: 81-91, 1995
21. Spencer JR, Bissell SR, Sanborn JR, Schneider FA, Margetich SS, Krieger RI: Chlorothalonil exposure of workers on harvesters. Toxicol Lett 55: 99-107, 1991
22. Moffat AS: New chemicals seek to outwit insect pests. Science 261: 550-551, 1993
23. Devanesan PD, RamaKrishna NV, Todorovic R, Rogan EG, Cavalieri EL, Jeong H, Jankowiak R, Small GJ: Identification and quantitation of benzo[α]pyrene-DNA adducts formed by rat liver microsomes in vitro. Chem Res Toxicol 5: 302-309, 1992
24. 32P-postlabeling and multifraction contact-transfer thin-layer chromatography. Fundam Appl Toxicol 23: 308-312, 1994
25. 32P-postlabeling. Carcinogenesis 17: 109-114, 1996
26. Gupta RC: Non-random binding of the carcinogen N-hydroxy-2-acetylaminofluorene to repetitive sequences in rat liver DNA in vivo. Proc Natl Acad Sci USA 81: 6943-6947, 1984
27. 32P-postlabeling assay after either 1-butanol extraction or nuclease P1 treatment. Cancer Lett 45: 7-12, 1989
28. 32P-postlabeling analysis of bulky aromatic adducts. IARC Sci Publ 124: 11-23, 1993
29. Gallagher EP, Kedderis GL, Di Giulio RT: Glutathione S-transferase-mediated chlorothalonil metabolism in liver and gill subcellular fractions of channel catfish. Biochem Pharmacol 42: 139-145, 1991
30. 32P-postlabeling detection of DNA-adducts in peripheral white blood-cells of greenhouse floriculturists from western Liguria, Italy. Cancer Epidemiology Biomarkers and Prevention 5: 361-369, 1996
31. Bolognesi C, Peluso M, Degan P, Rabboni R, Munnia A, Abbondandolo A: Genotoxic effects of the carbamate insecticide, methyomyl. II. In vivo studies with pure compound and the technical formulation, 'Lannate 25'. Environ Mol Mutagen 24: 235-242, 1994
32. Bessi H, Rast C, Rether B, Nguyen-Ba G, Vasseur P: Synergistic effects of chlordane and TPA in multistage morphological transformation of SHE cells. Carcinogenesis 16: 237-244, 1995
33. Vulimiri SV, Gupta S, Smith CV, Moorthy B, Randerath K: Rapid decreases in indigenous covalent DNA modifications (I-compounds) of male Fischer-344 rat liver DNA by diquat treatment. Chem Biol Interact 95: 1-16, 1995
34. Randerath K, Li D, Moorthy B, Randerath E: I-compounds - endogenous DNA markers of nutritional status, ageing, tumor promotion and carcinogenesis. IARC Sci Publ 124: 157-165, 1993
35. Laouedj A, Schenk C, Pfohl Leszkowicz A, Keith G, Schontz D, Guillemaut P, Rether B: Detection of DNA adducts in declining hop plants grown on field formerly treated with heptachlor, a persistent insecticide. Environ pollut 90: 409-414, 1995
36. Gopalaswamy UV, Nair CK: DNA binding and mutagenicity of lindane and its metabolites. Bull Environ Contain Toxicol 49: 300-305, 1992
37. Brown MA, Kimmel EC, Casida JE: DNA adduct formation by alachlor metabolites. Life Sciences 43: 2087-2094, 1988
38. Colacci A, Mazzulo M, Arfellini G, Prodi G, Grilli S: In vitro microsome- and cytosol-mediated binding of 1,2-dichloroethane and 1,2-dibromoethane with DNA. Cell Biol Toxicol 1: 45-55, 1985
39. Stokes L, Stark A, Marshall E, Narang A: Neurotoxicity among pesticide applicators exposed to organophosphates. Occup Environ Med 52: 648-653, 1995
40. Cantor KP, Blair A, Everett G, Gibson R, Burmeister LF, Brown LM, Schuman L, Dick FR: Pesticides ad other agricultural risk factors for non-Hodgkin's lymphoma among men in Iowa and Minnesota. Cancer Res 52: 2447-2455, 1992
41. Brouwer DH, Brouwer R, De Mik G, Maas CL, van Hemmen JJ: Pesticides in the cultivation of carnations in greenhouses: Part I - Exposure and concomitant health risk. Am Ind Hyg Assoc J 53: 575-581, 1992