Effect of 1,25(OH)2 vitamin D3 on circulating insulin-like growth factor-I and β2 microglobulin in patients with osteoporosis

Calcified Tissue International

Volumn 60, Issue 3, 1997, Pages 236-239

  Zofkova I ^a   Kancheva, R L ^a   Bendlova B ^a  

^a INSTITUTE OF ENDOCRINOLOGY   (Czech Republic)

Author keywords

2 microglobulin; 1,25(OH)2vitamin D3; Insulin like growth factor I; Osteocalcin

Indexed keywords

BETA 2 MICROGLOBULIN; CALCITRIOL; OSTEOCALCIN; PARATHYROID HORMONE; SOMATOMEDIN C;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HORMONAL REGULATION; HORMONE BLOOD LEVEL; HUMAN; OSTEOPOROSIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL;

BETA 2-MICROGLOBULIN; CALCITRIOL; CALCIUM; FEMALE; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MIDDLE AGED; OSTEOCALCIN; OSTEOPOROSIS; PARATHYROID HORMONE;

EID: 0031044225     PISSN: 0171967X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002239900221     Document Type: Article

References (22)

1. Canalis E, McCarthy T, Centrella M (1988) Isolation and characterization of insulin-like growth factor I (somatomedin-C) from cultures of fetal rat calvariae. Endocrinology 122:22-27
2. McCarthy TL, Centrella M, Canalis E (1989) Parathyroid hormone enhances the transcript and polypeptide levels of insulin-like growth factor I in osteoblast-enriched cultures from fetal rat bone. Endocrinology 124:1247-1253
3. Wong GL, Kotliar D, Schlaeger D, Brandes SJ (1990) IGF-I production by mouse osteoblasts. J Bone Miner Res 5:133-140
4. Okazaki R, Conover CA, Harris SA, Slelsberg TC, Riggs BL (1995) Normal human osteoblast-like cells consistently express genes for insulin-like growth factors I and II but transformed human osteoblast cell lines do not. J Bone Miner Res 10:788-795
5. Schmid Ch, Schläpfer I, Keller A, Waldvogel M, Froesch ER, Zapf J (1995) Effects of insulin-like growth factor (IGF) binding proteins (BPs)-3 and -6 on DNA synthesis of rat osteoblasts: further evidence for a role of auto-paracrine IGF I but not IGF II in stimulating osteoblast growth. Biochem Biophys Res Commun 212:242-248
6. Johansson AG, Lindh E, Ljunghall S (1992) Insulin-like growth factor I stimulates bone turnover in osteoporosis. Lancet 339:1619
7. Slootweg MC, Hoogerbrugge CM, de Poorter TL, Duursma SA, van Buul-Offers SC (1990) The presence of classical insulin-like growth factor (IGF) type-I and -II receptors on mouse osteoblasts: autocrine/paracrine growth effect of IGFs? J Endocrinol 125:271-277
8. Liesegang P, Romalo G, Sudmann M, Wolf L, Schweikert H-U (1994) Human osteoblast-like cells contain specific, saturable, high-affinity glucocorticoid, androgen, estrogen, and 1α,25-dihydroxycholecalciferol receptors. J Androl 15:194-199
9. Beneton MN, Yates AJ, Rogers S, McCloskey EV, Kanis JA (1991) Stanozolol stimulates remodeling of trabecular bone and net formation of bone at the endocortical surface. Clin Sci Colch 81:543-549
10. Martin TJ, Allan EH, Fukumoto S, Moseley JM (1995) Some aspects of the anabolic action of parathyroid hormone. Miner Electrolyte Metab 21:87-90
11. Ernst M, Rodan GA (1991) Estradiol regulation of insulin-like growth factor-I expression in osteoblastic cells: evidence for transcriptional control. Mol Endocrinol 5:1081-1089
12. McCarthy TL, Centrella M, Canalis E (1992) Constitutive synthesis of insulin-like growth factor-II by primary osteoblast-enriched cultures from fetal rat calvariae. Endocrinology 130:1303-1308
13. Watson P, Lazowski D, Han V, Fraher L, Steer B, Hodsman A (1995) Parathyroid hormone restores bone mass and enhances osteoblast insulin-like growth factor I gene expression in ovariectomized rats. Bone 16:357-365
14. 2 microglobulin. Endocrinology 121:1198-1200
15. +2 influx-dependent nongenomic pathways. J Nutr 125:1699S-1703S
16. 3 modulate the synthesis of insulin-like growth factor-I in osteoblast-like cells. Calcif Tissue Int 48: 278-282
17. Finkelman RD, Linkhart TA, Mohan S, Lau KH, Baylink DJ, Bell NH (1991) Vitamin D deficiency causes a selective reduction in deposition of transforming growth factor beta in rat bone: possible mechanism for impaired osteoinduction. Proc Natl Acad Sci USA 88:3657-3660
18. 3 and growth hormone therapy on serum osteocalcin levels in children with growth hormone deficiency. Bone Miner 21:151-156
19. 2 microglobulin in osteoporotic postmenopausal women. J Rheumatol 19:1753-1755
20. 3-regulated expression of the eukaryotic genome. Nutr Rev 52: 376-382
21. 3 and pancreatic β-cell function: vitamin D receptors, gene expression, and insulin secretion. Endocrinology 134:1602-1610
22. 3 in T-47D human breast cancer cells. J Steroid Biochem Molec Biol 54:147-153