Evaluation of cardiac subacute toxicity of epirubicin, chlorambucil, cisplatin, methotrexate and a homo-aza-steroid ester with antitumor activity in rats using serum biochemical parameters

Arzneimittel-Forschung/Drug Research

Volumn 47, Issue 1, 1997, Pages 92-96

  Pispirigos, Kyriakos ^a   Paradelis, Athanasios G ^b   Karakiulakis, George ^b  

^a UNIVERSITY OF PATRAS   (Greece)

^b ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

Author keywords

antineoplastic drugs; azasteroid antitumor agent, creatinine kinase isoenzyme, in vivo studies, subacute cardiotoxicity; chlorambucil; cisplatin; epirubicin; methotrexate

Indexed keywords

3BETA HYDROXY 13ALPHA AMINO 13,17 SECO 5ALPHA ANDROSTAN 17 OIC 13,17 LACTAM [4 [BIS(2 CHLOROETHYL)AMINO]PHENYL]ACETATE; ASPARTATE AMINOTRANSFERASE; CHLORAMBUCIL; CISPLATIN; CREATINE KINASE MB; EPIRUBICIN; ISOENZYME; LACTATE DEHYDROGENASE; METHOTREXATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BLOOD ANALYSIS; CARDIOTOXICITY; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ACTIVITY; INTRAPERITONEAL DRUG ADMINISTRATION; NONHUMAN; RAT;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; ANTIMETABOLITES, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC AGENTS, ALKYLATING; ANTINEOPLASTIC AGENTS, HORMONAL; ASPARTATE AMINOTRANSFERASES; BODY WEIGHT; CHLORAMBUCIL; CISPLATIN; CREATINE KINASE; EPIRUBICIN; HEART DISEASES; ISOENZYMES; L-LACTATE DEHYDROGENASE; METHOTREXATE; RATS;

EID: 0031043883     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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