T cell receptor-ζ and granzyme B expression in mononuclear cell infiltrates in normal colon mucosa and colon carcinoma

Gut

Volumn 40, Issue 1, 1997, Pages 113-119

  Mulder, W M C ^a   Bloemena, E ^a   Stukart, M J ^a   Kummer, J A ^a   Wagstaff, J ^a   Scheper, R J ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Carcinoma; Colon; Granzyme B; Immune suppression; Lymphocyte; TCR

Indexed keywords

CD3 ANTIGEN; CD8 ANTIGEN; GRANZYME B; T LYMPHOCYTE RECEPTOR;

ARTICLE; COLON CARCINOMA; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNE DEFICIENCY; IMMUNOHISTOCHEMISTRY; LYMPHOCYTIC INFILTRATION; MONONUCLEAR CELL; PRIORITY JOURNAL;

EID: 0031043487     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.40.1.113     Document Type: Article

References (33)

1. Svennevig JL, Lunde OC, Holter J, Björgsvik D. Lymphoid infiltration and prognosis in colorectal carcinoma. Br J Cancer 1984; 49: 375-7.
2. Jass JR, Morson BC. Reporting colorectal cancer. J Clin Pathol 1987;40:1016-23.
3. Miescher S, Whiteside TL, Moretta L, Von Fliedner V. Clonal and frequency analysis of tumor-infiltrating T-lymphocytes from human solid tumors. J Immunol 1987; 138: 4004-11.
4. Itoh K, Platsoucas CD, Balch CM. Autologous tumor-specific cytotoxic T lymphocytes in the infiltrate of human metastatic melanomas. Activation by interleukin 2 and autologous tumor cells, and involvement of the T cell receptor. J Exp Med 1988; 168: 1419-41.
5. Yanelli JR, Crumpacker DB, Good RW, Friddell CD, Poston R, Horton S, et al. Use of anti-CD3 monoclonal antibody in the generation of effector cells from human solid tumors for use in cancer biotherapy. J Immunol Meth 1990; 1: 91-100.
6. Whiteside TL, Jost LM, Herbermann RB. Tumor-infiltrating lymphocytes. Potential and limitations to their use for cancer therapy. Crit Rev Oncol Hematol 1992; 12: 25-47.
7. Mizoguchi H, O'Shea JJ, Longo DL, Loeffler CM, McVicar DW, Ochoa AC. Alterations in signal transduction molecules in T lymphocytes from tumor-bearing mice. Science 1992; 258: 1795-8.
8. Rudd CE, Janssen O, Cai Y-C, Da Silva AJ, Raab M, Prasad KVS. Two-step TCRzeta/CD3-CD4 and CD28 signaling in T cells: SH2/SH3 domains, protein-tyrosine and lipid kinases. Immunol Today 1994; 15: 225-34.
9. Wegener A-MK, Letourneur F, Hoeveler A, Brocker T, Luton F, Malissen B. The T cell receptor/CD3 complex is composed of at least two autonomous transduction modules. Cell 1992; 68: 83-95.
10. lck in T-cells infiltrating human renal cell carcinoma. Cancer Res 1993; 53: 5613-6.
11. Nakagomi H, Petersson M, Magnusson I, Juhlin C, Matsuda M, Mellstedt H, et al. Decreased expression of the signal-transducing zeta chains in tumor-infiltrating T-cells and NK cells of patients with colorectal carcinoma. Cancer Res 1993; 53: 5610-2.
12. Matsuda M, Petersson M, Lenkei R, Taupin J-L, Magnusson I, Mellstedt H, et al. Alterations in the signal-transducing molecules of T cells and NK cells in colorectal tumor-infiltrating, gut mucosal and peripheral lymphocytes: correlation with the stage of the disease. Int J Cancer 1995; 61: 765-72.
13. Kummer JA, Wever PC, Kamp AM, ten Berge IJM, Hack CE, Weening JJ. Expression of granzyme A and B proteins by cytotoxic lymphocytes involved in acute renal allograft rejection. Kidney Int 1995; 47: 70-7.
14. Smyth MJ, Trapani JA. Granzymes: exogenous proteinases that induce target cell apoptosis. Immunol Today 1995; 16: 202-6.
15. Peters PJ, Borst J, Oorschot V, Fukuda M, Krähenbühl O, Tschopp J, et al. Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perform and granzymes. J Exp Med 1991; 173: 1099-109.
16. Liu C-C, Rafii S, Granelli-Piperno A, Trapani JA, Young JD-E. Perform and serine esterase gene expression in stimulated human T cells. Kinetics, mitogen requirements, and effects of cyclosporin A. J Exp Med 1989; 170: 2105-18.
17. + T cells. J Immunol 1992; 149: 949-56.
18. Anderson P, Blue M-L, O'Brien C, Schlossman SF. Monoclonal antibodies reactive with the T cell receptor zeta chain: production and characterization using a new method. J Immunol 1989; 143: 1899-904.
19. Kummer JA, Kamp AM, van Katwijk M, Brakenhoff JPJ, Radosevic K, Van Leeuwen AM, et al. Production and characterization of monoclonal antibodies raised against recombinant human granzymes A and B and showing cross reactions with the natural proteins. J Immunol Meth 1993; 163: 77-83.
20. Mason DY, Cordell JL, Gaulard P, Tse AGD, Brown MH. Immunohistological detection of human cytotoxic/suppressor T cells using antibodies to a CD8 peptide sequence. J Clin Pathol 1992; 45: 1084-8.
21. Bankfalvi A, Navabi H, Bier B, Böcker W, Jasani B, Schmid KW. Wet autoclave pretreatment for antigen retrieval in diagnostic immunohistochemistry. J Pathol 1994; 174: 223-8.
22. Merchenthaler I, Stankovics J, Gallyas F. A highly sensitive one-step method for silver intensification of the nickel-diaminobenzidine endproduct of peroxidase reaction. J Histochem Cytochem 1989; 37: 1563-5.
23. Bloemena E, Gall H, Ransom JH, Pomato N, Murray JH, Bos E, et al. Delayed-type hypersensitivity reactions to tumor-associated antigens in colon carcinoma patients immunized with an autologous tumor cell/Bacillus Calmette-Guérin vaccine. Cancer Res 1993; 53: 1-4.
24. Flens MJ, Mulder WMC, Bril H, Von Blomberg van de Flier MBE, Scheper RJ, Van Lier RAW. Efficient expansion of tumor-infiltrating lymphocytes from solid tumors by stimulation with combined CD3 and CD28 monoclonal antibodies. Cancer Immunol Immunother 1993; 37: 323-8.
25. Umpleby HC, Heinemann D, Symes MO, Williamson RCN. Expression of histocompatibility antigens and characterization of mononuclear cell infiltrates in normal and neoplastic colorectal tissues of humans. J Natl Cancer Institute 1985; 74: 1161-8.
26. Norazmi MN, Hohmann AW, Skinner JM, Jarvis LR, Bradley J. Density and phenotype of tumour-associated mononuclear cells in colonic carcinomas determined by computer-assisted video image analysis. Immunology 1990; 69: 282-6.
27. Østenstadt B, Lea T, Schlichting E, Harboe M. Human colorectal tumour infiltrating lymphocytes express activation markers and the CD45RO molecule, showing a primed population of lymphocytes in the tumour area. Gut 1994; 35: 382-7.
28. Guerder S. Carding SR, Flavell RA. B7 costimulation is necessary for the activation of the lytic function in cytotoxic T lymphocyte precursors. J Immunol 1995; 155: 5167-74.
29. Nakanishi H, Monden T, Morimoto H, Kobayashi T, Shimano T, Mori T. Perform expression in lymphocytes infiltrated to human colorectal cancer. Br J Cancer 1991; 64: 239-42.
30. Shores EW, Huang K, Tran T, Lee E, Grindberg A, Love PE. Role of TCR-ζ chain in T cell development and selection. Science 1994; 266: 1047-50.
31. Ebert EC, Robets AI, Devereux D, Nagase H. Selective immunosuppressive action of a factor produced by colon cancer cells. Cancer Res 1990; 50: 6158-61.
32. Ebert EC, Roberts AI, O'Connell SM, Robertson FM, Nagase H. Characterization of an immunosuppressive factor derived from colon cancer cells. J Immunol 1987; 138: 2161-8.
33. Qiao L, Schürmann G, Betzler M, Meuer SC. Activation and signaling status of human lamina propria T lymphocytes. Gastroenterology 1991; 101: 1529-36.