Dimeric binding of the mouse germ cell nuclear factor

European Journal of Biochemistry

Volumn 244, Issue 1, 1997, Pages 120-127

  Borgmeyer, Uwe ^a  

^a UNIVERSITY OF HAMBURG   (Germany)

Author keywords

DNA binding dimerization; Germ cell nuclear factor; Nuclear hormone receptor; Orphan receptor

Indexed keywords

CELL NUCLEUS RECEPTOR; RETINOID X RECEPTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DELETION MUTANT; DNA BINDING; ELECTROPHORESIS; GENE EXPRESSION; GERM CELL; IN VITRO STUDY; INSECT; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN STRUCTURE;

EID: 0031042654     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1432-1033.1997.00120.x     Document Type: Article

References (27)

1. Beato, M., Herrlich, P. & Schütz, G. (1995) Steroid hormone receptors: many actors in search of a plot, Cell 83, 851-857.
2. Bourguet, W., Ruff, M., Chambon, P., Gronemeyer, H. & Moras, D. (1995) Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-α. Nature 375, 377-382.
3. Bugge, T. H., Pohl, J., Lonnoy, O. & Stunnenberg, H. G. (1992) RXRα, a promiscous partner of retinoic acid and thyroid hormone receptors, EMBO J. 11, 1409-1418.
4. Chen, F., Cooney, A. J., Wang, Y., Law, S. W. & O'Malley, B. W. (1994) Cloning of a novel orphan receptor (GCNF) expressed during germ cell development, Mol. Endocrinol. 8, 1434-1444.
5. Dollé, P. Fraulob, V., Kastner, P. & Chambon, P. (1994) Developmental expression of murine retinoid X receptor (RXR) genes. Mech. Dev. 45, 91-104.
6. Dreyer, C., Krey, G., Keller, H., Givel, F., Helftenbein, G. & Wahli, W. (1992) Control of the peroxisomal β-oxidation pathway by a novel family of nuclear hormone receptors. Cell 68, 879-887.
7. Evans, R. M. (1988) The steroid and thyroid hormone receptor superfamily, Science 240, 889-895.
8. Giguère, V., McBroom, L. D. & Flock, G. (1995) Determinants of target gene specificity for ROR α 1: monomeric DNA binding by an orphan nuclear receptor. Mol. Cell. Biol. 15, 2517-2526.
9. Green, S. & Chambon, P. (1988) Nuclear receptors enhance our understanding of transcription regulation. Trends Genet. 4, 309-314.
10. Harding, H. P. & Lazar, M. A. (1993) The orphan receptor Rev-ErbAα activates transcription via a novel response element, Mol. Cell. Biol. 13, 3113-3121.
11. Hirose, T., O'Brien, D. A. & Jetten, A. M. (1995) RTR: a new member of the nuclear receptor superfamily that is highly expressed in murine testis, Gene 152, 247-251.
12. Kliewer, S. A., Umesono, K., Mangelsdorf, D. J. & Evans, R. M. (1992a) Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and vitamin D3 signalling, Nature 355, 446-449.
13. Kliewer, S. A., Umesono, K., Noonan, D. J., Heyman, R. A. & Evans, R. M. (1992b) Convergence of 9-cis-retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors. Nature 358, 771-774.
14. Kliewer, S. A., Formam, B. M., Blumberg, B., Ong, E. S., Borgmeyer, U., Mangelsdorf, D. J., Umesono, K. & Evans, R. M. (1994) Differential expression and activation of a family of murine peroxisome proliferator-activated receptors. Proc. Natl Acad. Sci. USA 91, 7355-7359.
15. Lee, M. S., Kliewer, S. A., Provencal, J., Wright, P. E. & Evans, R. M. (1993) Structure of the retinoid X receptor α DNA binding domain: a helix required for homodimeric DNA binding, Science 260, 1117-1121.
16. Leid, M., Kastner, P., Lyons, R., Nakshatri, H., Saunders, M., Zacharewski, T., Chen, J.-Y., Staub, A., Garnier, J.-M., Mader, S. & Chambon, P. (1992) Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently, Cell 68, 377-395.
17. Mangelsdorf, D. J., Borgmeyer, U., Heyman, R. A., Zhou, J. Y., Ong, E. S., Oro, A. E., Kakizuka, A. & Evans, R. M. (1992) Characterization of three RXR genes that mediate the action of 9-cis-retinoic acid, Genes & Dev. 6, 329-344.
18. Mangelsdorf, D. J. & Evans, R. M. (1995) The RXR heterodimers and orphan receptors, Cell 83, 841-850.
19. Mangelsdorf, D. J., Thummel, C., Beato, M., Herrlich, P., Schütz, G., Umesono, K., Blumberg, B., Kastner, P., Mark, M., Chambon, P. & Evans, R. M. (1995) The nuclear receptor superfamily: the second decade, Cell 83, 835-839.
20. Perlmann, T. & Jansson, L. (1995) A novel pathway for vitamin A signalling mediated by RXR heterodimerization with NGFI. B and NURR1, Genes & Dev. 9, 769-782.
21. Rastinejad, F., Perlmann, T., Evans, R. M. & Sigler, P. B. (1995) Structural determinants of nuclear receptor assembly on DNA direct repeats, Nature 375, 203-211.
22. Süsens, U. & Borgmeyer, U. (1996) Characterization of the human germ cell nuclear factor gene, Biochim. Biophys. Acta 1309, 179-182.
23. Ueda, H., Sun, G.-C., Murata, T. & Hirose, S. (1992) A novel DNA-binding motif abuts the zinc finger domain of insect nuclear hormone receptor FTZ-F1 and mouse embryonal long terminal repeat-binding protein, Mol. Cell. Biol. 13, 5667-5672
24. Wilson, T. E., Fahrner, T. J. & Milbrandt, J. (1993) The orphan receptors NGFI-B and steroidogenic factor 1 establish monomer binding as a third paradigm of nuclear receptor-DNA interaction, Mol. Cell. Biol. 13, 5794-5804.
25. Yamamoto, K. R. (1985) Steroid receptor regulated transcription of specific genes and gene networks, Annu. Rev. Genet. 19, 209-252.
26. Yu, V. C., Delsert, C., Andersen, B., Holloway, J. M., Devary, O. V., Naeaer, A. M., Kim, S. Y., Boutin, J. M., Glass, C. K. & Rosenfeld, M. G. (1991) RXRβ: a coregulator that enhances binding of retinoic acid, thyroid hormone, and vitamin D receptors to their cognate response elements, Cell 67, 1251-1266.
27. Zentgraf, H., Frey, M., Schwinn, S., Tessmer, C., Willemann, B., Samstag, Y. & Velhagen, I. (1995) Detection of histidine-tagged fusion proteins by using a high-specific mouse monoclonal anti-histidine tag antibody, Nucleic Acids Res. 23, 3347-3348.