Effects of fructose-induced hypertriglyceridemia on hepatorenal toxicity of acetaminophen in rats. II. Role of enhancement of fructose metabolism and overproduction of triglyceride in the liver and kidney on hepatorenal toxicity of acetaminophen

Experimental and Toxicologic Pathology

Volumn 49, Issue 1-2, 1997, Pages 39-46

  Ishida, Katsuhiko ^a   Sakazume, Masashi ^a   Hirai, Nami ^a   Ikegami, Hisashi ^a   Sakai, Toshiharu ^a   Doi, Kunio ^b  

^a ASTELLAS PHARMA INC   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Acetaminophen; Fructose, hypertriglyceridemia; Hepatorenal toxicity; Hypertriglyceridemia

Indexed keywords

PARACETAMOL; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FRUCTOSE METABOLISM; HISTOPATHOLOGY; HYPERTRIGLYCERIDEMIA; INTRAPERITONEAL DRUG ADMINISTRATION; LIVER TOXICITY; MALE; NEPHROTOXICITY; NONHUMAN; RAT; TRIACYLGLYCEROL BLOOD LEVEL;

ANIMALIA;

EID: 0031042538     PISSN: 09402993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0940-2993(97)80056-5     Document Type: Article

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