Effect of burn injury on glucose and nitrogen metabolism in the liver: Preliminary studies in a perfused liver system

Surgery

Volumn 121, Issue 3, 1997, Pages 295-303

  Yamaguchi, Yoshihiro ^a   Yu, Yong Ming ^a   Zupke, Craig ^a   Yarmush, David M ^a   Berthiaume, Francois ^a   Tompkins, Ronald G ^a   Yarmush, Martin L ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b Shriners Burns Institute   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BURN; DISEASE SEVERITY; ENTERIC FEEDING; GLUCONEOGENESIS; GLUCOSE METABOLISM; LIVER METABOLISM; LIVER PERFUSION; NITROGEN METABOLISM; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT; UREA CYCLE;

EID: 0031042460     PISSN: 00396060     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0039-6060(97)90358-5     Document Type: Article

References (48)

1. Long CL, Schaffel N, Geiger JW. Metabolic response to injury and illness: estimation of energy and protein needs from indirect calorimetry and nitrogen balance. JPEN 1979;3:452-6.
2. Wolfe RR, Durkot MJ, Allsop JR, Burke JF. Glucose metabolism in severely burned patients. Metabolism 1979;28:1031-8.
3. Burke JF, Wolfe RR, Mullany CJ, Mathews DE, Bier DM. Glucose requirements following burn injury. Ann Surg 1979;190:274-85.
4. Bell SJ, Molnar JA, Krasker WS, Burke JF. Prediction of total urinary nitrogen from urea nitrogen for burned patients. J Am Diet Assoc 1985;85:1100-4.
5. Wolfe RR, Jahoor F, Hartl WH. Protein and amino acid metabolism after injury. Diabetes Metab Rev 1989;5:149-64.
6. Dudrick SJ. Past, present, and future of nutritional support. In: Dudrick SJ, editor. Current strategies in surgical nutrition. Surg Clin North Am 1991;71:439-48.
7. Tompkins RG, Burke JF. Burn therapy 1985: acute management. Intensive Care Medicine 1986;12:289-95.
8. Jahoor F, Desai M, Herndon DN, Wolfe RR. Dynamics of the protein metabolic response to burn injury. Metabolism 1988;37:330-7.
9. Yu YM, Young VR, Castillo L, Chapman TE, Tompkins RG, Ryan CM, et al. Plasma arginine and leucine kinetics and urea production rates in burn patients. Metabolism 1995;44:659-66.
10. Yu YM, Ryan CM, Burke JF, Tompkins RG, Young VR. Relationships among arginine, citrulline, ornithine and leucine kinetics in adult burn patients. Am J Clin Nutr 1995;62:960-8.
11. Kinney JM. Metabolic responses of the critically ill patient. Crit Care Clin 1995;11:569-86.
12. Carter EA, deRojas-Walker T, Tamir S, Tannenbaum SR, Yu YM, Tompkins RG. Nitric oxide production is intensely and persistently increased in tissues by thermal injury. Biochem J (London) 1994;304:201-4.
13. Teo TC, DeMichele SJ, Selleck KM, Babaya VK, Blackburn GL, Bistrian BR. Administrations of structured lipid composed of MCT and fish oil reduces net protein catabolism in enterally fed burned rats. Ann Surg 1989;210:100-7.
14. Mortimore GE. Liver perfusion: an in vitro technique for the study of intracellular protein turnover and its regulation in vivo. Proc Nutr Sco (London) 1984;43:161-77.
15. Swendseid ME, Hickson JB, Friedrich BW. Effect of nonessential nitrogen supplements on growth and on the amino acid content in plasma and muscle of weaning rats fed a low-protein diet. J Nutr 1962;78:115-9.
16. Tolman EL, Schworer CM, Jefferson LS. Effects of hypophysectomy on amino acid metabolism and gluconeogenesis in the perfused rat liver. J Biol Chem 1973;248:4552-60.
17. Searcy RL, Cough GS, Korotzer JL, Berquist LM. Evaluation of a new technique for estimation of urea nitrogen in serum. Am J Med Technol 1961;27:255-62.
18. Huggett AG, Nixon DA. Enzymic determination of blood glucose. Biochem J 1957;66:12-4.
19. Walaas O, Walaas E. Effect of epinephrine on rat diaphragm. J Biol Chem 1950;187:769-76.
20. Hems R, Ross BD, Berry MN, Krebs HA. Gluconeogenesis in the perfused rat liver. Biochem J 1966;101:284-92.
21. Menahan LA, Wieland O. Interactions of glucagon and insulin on the metabolism of perfused livers from fasted rats. Eur J Biochem 1969;9:55-62.
22. Menahan LA, Wieland O. The role of endogenous lipid in gluconeogenesis and ketogenesis of perfused rat liver. Eur J Biochem 1969;9:182-8.
23. 14C] pyruvate in the perfused rat liver. Eur J Biochem 1967;2:182-6.
24. Riedel GL, Scholle JL, Shepherd AP, Ward WF. Effects of hematocrit on oxygenation of the isolated perfused rat liver. Am J Physiol 1983;245:G769-74.
25. Wu G, Gunnasekara A, Brunengraber H, Marliss EB. Effects of extracellular pH, CO2, and HCO3 on ketogenesis in perfused rat liver. Am J Physiol 1991;261:E221-6.
26. Dahn MS, Mitchell RA, Berberoglu ED, Lange P. The isolated perfused rat liver as an experimental model. Am Surg 1992;9:521-5.
27. Nishimura M, Fedorov S, Uyeda K Glucose-stimulated synthesis of fructose 2,6-bisphosphate in rat liver. J Biol Chem 1994;269:26100-6.
28. Harper AE. Diet and plasma amino acids. Am J Clin Nutr 1968;21:358-66.
29. Royle GT, Wolfe RR, Burke JF. Glucose and fatty acid kinetics in fasted rats. Metabolism 1982;31:279-83.
30. Younes H, Garleb K, Behr S, Remesy C, Demigne C. Fermentable fibers or oligosaccharides reduce urinary nitrogen excretion by increasing urea disposal in the rat cecum. J Nutr 1995;125:1010-6.
31. Ratner S. Enzymes of arginine and urea synthesis. Adv Enzymol 1973;39:1-90.
32. Meijer AJ, Lamers WH, Chamuleau RAFM. Nitrogen metabolism and ornithine cycle function. Physiol Rev 1990;70:701-48.
33. Wilmore DW, Goodwill CW, Aulick LH, Powanda MC, Mason AD, Pruitt BA. Effect of injury and infection on visceral metabolism and circulation. Ann Surg 1980;192:491-504.
34. Souba WW, Austgen TR. Interorgan glutamine flow following surgery and infection. JPEN 1990;4(suppl):90-3s.
35. Souba WW, Pacitti AJ. How amino acids get into cell: mechanisms, models, menus, and mediators. JPEN 1992;16:569-78.
36. Wolfe RR. Metabolic response to burn injury: nutritional implications. Semin Nephrol 1993;13:382-90.
37. Beisel W, Wannemacher RW. Gluconeogenesis, ureagenesis, and ketogenesis during sepsis. JPEN 1980;4:277-85.
38. Krebs HA, Lund P, Stubbs M. Interrelationships between gluconeogenesis and urea synthesis. In: Hanson RW, Mehlman MA, editors. Gluconeogenesis: its regulation in mammalian species. New York: Wiley Intersciences, 1976:269-91.
39. Paidas CN, Chin M, Clemens MG. Preferential hepatic oxidation of alanine during sepsis [abstract]. Circ Shock 1990;31:21.
40. Ohtake Y, Clemens MG. Interrelationship between hepatic ureagenesis and gluconeogenesis in early sepsis. Am J Physiol 1991;260:E453-8.
41. Newsholme EA, Leech AR, editors. Biochemistry for the medical sciences. New York: John Wiley & Sons, 1983:417-26.
42. Young VR, El-Khoury AE. The notion of the nutritional essentiality of amino acids, revisited, with a note on the indispensable amino acid requirements in adults. In: Cynober LA, editor. Amino acid metabolism and therapy in health and nutritional disease. London: CRC Press, 1995:191-232.
43. 15N]leucine and substrate balance studies. Am J Physiol 1990;259:E36-51.
44. Rothwell NJ, Little RA, Rose JG. Brown adipose tissue activity and oxygen consumption after scald injury in the rat. Circ Shock 1991;33:33-6.
45. Williamson DH, Lund P, Krebs HA. The redox state of free nicotinamide-adenine dinucleotides in the cytoplasm and mitochondria of rat liver. Biochem J 1967:103:514-27.
46. Ozawa K. Liver surgery approached through the mitochondria. Tokyo: Medical Tribune, 1992.
47. Nakatani T, Spolter L, Kobayashi K. Arterial ketone body ratio as a parameter of hepatic mitochondrial redox state during and after hemorrhagic shock. World J Surg 1995;19:592-6.
48. Kagawa R, Mori K, Yamamoto Y, Fujii T, Shimabukuro T, Morimoto T, et al. Prognostic implications of the response of arterial ketone body ratio and insulin secretion to glucose load in major hepatectomy. World J Surg 1995;19:603-7.