Lesser alkaloids of cocaine-bearing plants. Part I: Nicotinoyl-, 2'- pyrroloyl, and 2'- and 3'-furanoylocgonino methyl ester - Isolation and mass spectral characterization of four now alkaloids of South American Erythroxylum coca var. coca

Journal of Forensic Sciences

Volumn 42, Issue 2, 1997, Pages 246-255

  Moore, James M ^a,b   Casale, John F ^a  

^a Spec Test and Research Laboratory   (United States)

^b DEA Spec Test Research Laboratory   (United States)

Author keywords

alkaloids; chemistry; coca leaf; cocaine; Erythroxylum; Erythroxylum coc var. coca; forensic science; gas chromatography; isolation; mass spectrometry; substance abuse

Indexed keywords

ALKALOID; ECGONINE METHYL ESTER;

ARTICLE; CHEMICAL ANALYSIS; COCA; GAS CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; PLANT LEAF; PRIORITY JOURNAL; SOUTH AMERICA; SUBSTANCE ABUSE;

EID: 0031042225     PISSN: 00221198     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

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2. Moore JM, Casale JF, Klein RFX, Cooper DA, Lydon J. Determination and in-depth chromatographic analyses of alkaloids in South American and greenhouse-cultivated coca leaves. J Chromatog 1994;659:163-75.
3. Turner CE, Urbanek BS, Wall GM, Waller CW. Cocaine - An annotated bibliography. Vols. I and II, University Press of Mississippi, Research Institute of Pharmaceutical Sciences, University of Mississippi, Oxford, MS, 1988.
4. Moore JM. Identification of cis- and trans-cinnamoylcocaine in illicit cocaine seizures. J Association of Official Analytical Chemists 1973;56:1199-205.
5. Moore JM, Cooper DA, Lurie IS, Kram TC, Carr S, Harper C, Yeh J. Capillary gas chromatographic-electron capture detection of coca-leaf-related impurities in illicit cocaine: 2,4-diphenylcyclobutane-1,3-dicarboxylic acids, 1,4-diphenylcyclobutane-2,3-dicarboxylic acids and their alkaloidal precursors, the truxillines. J Chromatog 1987;410:297-318.
6. Ensing JG, de Zeuuw RA. Detection, isolation, and identification of truxillines in illicit cocaine by means of thin-layer chromatography and mass spectrometry. J Forensic Sci 1991;36:1299-311.
7. Moore JM, Cooper DA. The application of capillary gas chromatography-electron capture detection in the comparative analyses of illicit cocaine samples. J Forensic Sci 1993;38:1286-304.
8. Casale JF, Moore JM. 3′,4′,5′-Trimethoxy-substituted analogues of cocaine, cis-/trans-cinnamoylcocaine and tropacocaine: Characterization and quantitation of new alkaloids in coca leaf, coca paste and refined illicit cocaine. J Forensic Sci 1994;39:462-72.
9. Casale JF, Moore JM. Detection and determination of pseudococaine in coca leaves and illicit cocaine samples. J Forensic Sci 1994;39:1537-43.
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12. Al-Yahya MAI, Evans WC, Grout RJ. Alkaloids of the genus Erythroxylum. Part 2. E. Dekindtii (Engl.) OE Schultz. J Chemical Soc Perkin I 1979;9:2130-32.
13. United States Pharmacopeia, XIX, United States Pharmacopeial Convention, Rockville, MD, (1975) 654.
14. Moore JM, Hays PA, Cooper DA, Casale JF, Lydon J. 1-Hydroxytropacocaine: An abundant alkaloid of Erythroxylum novogranatense var. novogranatense and var. truxillense. J Phytochemistry 1994; 36:357-60.
15. Budzikiewicz H, Djerassi C, Williams DH. Interpretation of mass spectra of organic compounds. Holden-Day, Inc., San Francisco, CA, 1964.