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Volumn 61, Issue 1, 1997, Pages 33-39

N-acetyl-L-cysteine-induced up-regulation of HIV-1 gene expression in monocyte-derived macrophages correlates with increased NF-κB DNA binding activity

Author keywords

AIDS therapy; chloramphenicol acetyltransferase assays; oxygen radical scavengers; transcription factor

Indexed keywords

ACETYLCYSTEINE; CHLORAMPHENICOL ACETYLTRANSFERASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN;

EID: 0031042011     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1002/jlb.61.1.33     Document Type: Article
Times cited : (10)

References (31)
  • 1
    • 0025887045 scopus 로고
    • Regulation of HIV-1 gene expression
    • Cullen, B. R. (1991) Regulation of HIV-1 gene expression. FASEB J. 5, 2361-2368.
    • (1991) FASEB J. , vol.5 , pp. 2361-2368
    • Cullen, B.R.1
  • 2
    • 0026573663 scopus 로고
    • Cellular transcription factors involved in the regulation of HIV-1 gene expression
    • Gaynor, R. (1992) Cellular transcription factors involved in the regulation of HIV-1 gene expression. AIDS 6, 347-363.
    • (1992) AIDS , vol.6 , pp. 347-363
    • Gaynor, R.1
  • 3
    • 0027536852 scopus 로고
    • The inducible transcription factor NF-κB: Structure-function relationship of its protein subunits
    • Grimm, S., Baeuerle, P. A. (1993) The inducible transcription factor NF-κB: structure-function relationship of its protein subunits. Biochem. J. 290, 297-308.
    • (1993) Biochem. J. , vol.290 , pp. 297-308
    • Grimm, S.1    Baeuerle, P.A.2
  • 4
    • 0027168447 scopus 로고
    • NF-κB controls expression of inhibitor IKBα: Evidence for an inducible autoregulatory pathway
    • Sun, S-C., Ganchi, P., Ballard, D., Creene, W. C. (1993) NF-κB controls expression of inhibitor IKBα: evidence for an inducible autoregulatory pathway. Science 259, 1912-1915.
    • (1993) Science , vol.259 , pp. 1912-1915
    • Sun, S.-C.1    Ganchi, P.2    Ballard, D.3    Creene, W.C.4
  • 5
    • 0027451924 scopus 로고
    • In vivo control of NF-κB activation by IκBα
    • Rice, N., Ernst, M. (1993) In vivo control of NF-κB activation by IκBα. Eur. Mol. Biol. Org. J. 12, 4685-4695.
    • (1993) Eur. Mol. Biol. Org. J. , vol.12 , pp. 4685-4695
    • Rice, N.1    Ernst, M.2
  • 6
    • 0024502041 scopus 로고
    • Activation of HIV gene expression during monocyte differentiation by induction of NF-κB
    • Griffin, G. E., Leung, K., Folks, T. M., Kunkel, S., Nabel, G. J. (1989) Activation of HIV gene expression during monocyte differentiation by induction of NF-κB. Nature 339, 70-73.
    • (1989) Nature , vol.339 , pp. 70-73
    • Griffin, G.E.1    Leung, K.2    Folks, T.M.3    Kunkel, S.4    Nabel, G.J.5
  • 7
    • 0028604408 scopus 로고
    • Role for oxygen radicals in self-sustained HIV-1 replication in monocyte-derived macrophages: Enhanced HIV-1 replication by N-acetyl-L-cysteine
    • Nottet, H. S. L. M., van Asbeck, B. S., de Graaf, L., de Vos, N. M., Visser, M. R., Verhoef, J. (1994) Role for oxygen radicals in self-sustained HIV-1 replication in monocyte-derived macrophages: enhanced HIV-1 replication by N-acetyl-L-cysteine. J. Leukoc. Biol. 56, 702-707.
    • (1994) J. Leukoc. Biol. , vol.56 , pp. 702-707
    • Nottet, H.S.L.M.1    Van Asbeck, B.S.2    De Graaf, L.3    De Vos, N.M.4    Visser, M.R.5    Verhoef, J.6
  • 8
    • 0025677250 scopus 로고
    • Lntracellular thiols regulate activation of nuclear factor KB and transcription of human immunodeficiency virus
    • Staal, F. J. T., Roederer, M., Herzenberg, L. A., Herzenberg, L. A. (1990) lntracellular thiols regulate activation of nuclear factor KB and transcription of human immunodeficiency virus. Proc. Natl. Acad. Sci. USA 87, 9943-9947.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 9943-9947
    • Staal, F.J.T.1    Roederer, M.2    Herzenberg, L.A.3    Herzenberg, L.A.4
  • 9
    • 0027466035 scopus 로고
    • Thiol suppression of human immunodeficiency virus type 1 replication in primary cord blood monocyte-derived macrophages in vitro
    • Lioy, J., Ho, W-Z., Cutilli, J. R., Polin, R. A., Douglas, S. D. (1993) Thiol suppression of human immunodeficiency virus type 1 replication in primary cord blood monocyte-derived macrophages in vitro. J. Clin. Invest. 91, 495-498.
    • (1993) J. Clin. Invest. , vol.91 , pp. 495-498
    • Lioy, J.1    Ho, W.-Z.2    Cutilli, J.R.3    Polin, R.A.4    Douglas, S.D.5
  • 11
    • 0026588635 scopus 로고
    • HIV-induced cysteine deficiency and T-cell dysfunction - a rationale for treatment with N-acetylcysteine
    • Dröge, W., Eck, H. P., Mihm, S. (1992) HIV-induced cysteine deficiency and T-cell dysfunction - a rationale for treatment with N-acetylcysteine. Immunol. Today 13, 211-214.
    • (1992) Immunol. Today , vol.13 , pp. 211-214
    • Dröge, W.1    Eck, H.P.2    Mihm, S.3
  • 13
    • 0028988568 scopus 로고
    • Supplementation of N-acetylcysteine fails to increase glutathione in lymphocytes and plasma of patients with AIDS
    • Witschi, A., Junker, E., Schranz, C., Speck, R. F., Lauterburg, B. H. (1995) Supplementation of N-acetylcysteine fails to increase glutathione in lymphocytes and plasma of patients with AIDS. AIDS Res. Hum. Retroviruses 11, 141-143.
    • (1995) AIDS Res. Hum. Retroviruses , vol.11 , pp. 141-143
    • Witschi, A.1    Junker, E.2    Schranz, C.3    Speck, R.F.4    Lauterburg, B.H.5
  • 14
    • 0027407721 scopus 로고
    • Down-regulation of human immunodeficiency virus type 1 (HIV-I) production after stimulation of monocyte-derived macrophages infected with HIV-1
    • Nottet, H. S. L. M., de Graaf, L., de Vos, N. M., Bakker, L. J., van Strijp. J. A. G., Visser, M. R., Verhoef, J. (1993) Down-regulation of human immunodeficiency virus type 1 (HIV-I) production after stimulation of monocyte-derived macrophages infected with HIV-1. J. Infect. Dis. 167, 810-817.
    • (1993) J. Infect. Dis. , vol.167 , pp. 810-817
    • Nottet, H.S.L.M.1    De Graaf, L.2    De Vos, N.M.3    Bakker, L.J.4    Van Strijp, J.A.G.5    Visser, M.R.6    Verhoef, J.7
  • 15
  • 16
    • 0021967217 scopus 로고
    • Trans-activator gene of human T-lymphotropic virus type III (HTLV-III)
    • Arya, S. K., Guo, C., Josephs, S. F., Wong-Staal, F. (1985) Trans-activator gene of human T-lymphotropic virus type III (HTLV-III). Science 229, 69-73.
    • (1985) Science , vol.229 , pp. 69-73
    • Arya, S.K.1    Guo, C.2    Josephs, S.F.3    Wong-Staal, F.4
  • 17
    • 0021071029 scopus 로고
    • Cell-specific expression controlled by the 5′-flanking region of insulin and chemotrypsin genes
    • Walker, M. D., Edlund, T., Boulet, A. M., Rutter, W. J. (1983) Cell-specific expression controlled by the 5′-flanking region of insulin and chemotrypsin genes. Nature 306, 557-561.
    • (1983) Nature , vol.306 , pp. 557-561
    • Walker, M.D.1    Edlund, T.2    Boulet, A.M.3    Rutter, W.J.4
  • 18
    • 0000404279 scopus 로고
    • The Rous sarcoma virus long terminal repeat is a strong promoter when introduced into a variety of eukaryotic cells by DNA-mediated transfection
    • Gorman, C. M., Merlino, G. T., Willingham, M. C., Pastan, L., Howard, B. H. (1982) The Rous sarcoma virus long terminal repeat is a strong promoter when introduced into a variety of eukaryotic cells by DNA-mediated transfection. Proc. Natl. Acad. Sci. USA 79, 6777-6781.
    • (1982) Proc. Natl. Acad. Sci. USA , vol.79 , pp. 6777-6781
    • Gorman, C.M.1    Merlino, G.T.2    Willingham, M.C.3    Pastan, L.4    Howard, B.H.5
  • 19
    • 0024468977 scopus 로고
    • An enhancer located in a CpG-Island 3′ to the TCR/CD3-ε gene confers T lymphocyte-specificity to its promoter
    • Clevers, H., Lonberg, N., Dunlap, S., Lacy, E., Terhorst, C. (1989) An enhancer located in a CpG-Island 3′ to the TCR/CD3-ε gene confers T lymphocyte-specificity to its promoter. Eur. Mol. Biol. Org. J. 8, 2527-2535.
    • (1989) Eur. Mol. Biol. Org. J. , vol.8 , pp. 2527-2535
    • Clevers, H.1    Lonberg, N.2    Dunlap, S.3    Lacy, E.4    Terhorst, C.5
  • 20
    • 0024380087 scopus 로고
    • Rapid detection of octamer binding proteins in 'mini-extracts', prepared from a small number of cells
    • Schreiber, E., Matthias, P., Müller, M. M., Schaffner, W. (1989) Rapid detection of octamer binding proteins in 'mini-extracts', prepared from a small number of cells. Nucleic Acid Res. 17, 6419.
    • (1989) Nucleic Acid Res. , vol.17 , pp. 6419
    • Schreiber, E.1    Matthias, P.2    Müller, M.M.3    Schaffner, W.4
  • 21
    • 0025769988 scopus 로고
    • Activation of human monocyte-derived macrophages with lipopolysaccharide decreases human immunodeficiency virus replication in vitro at the level of gene expression
    • Bernstein, M. S., Tong-Starksen, S. E., Locksley, R. M. (1991) Activation of human monocyte-derived macrophages with lipopolysaccharide decreases human immunodeficiency virus replication in vitro at the level of gene expression. J. Clin. Invest. 88, 540-545.
    • (1991) J. Clin. Invest. , vol.88 , pp. 540-545
    • Bernstein, M.S.1    Tong-Starksen, S.E.2    Locksley, R.M.3
  • 22
    • 0027050407 scopus 로고
    • Phorbol ester reduces constitutive nuclear NFκB and inhibits HIV-1 production in mature human monocytic cells
    • Mufson, R. A., Myers, C., Turpin, J. A., Meltzer, M. S. (1992) Phorbol ester reduces constitutive nuclear NFκB and inhibits HIV-1 production in mature human monocytic cells. J. Leukoc. Biol. 52, 637-644.
    • (1992) J. Leukoc. Biol. , vol.52 , pp. 637-644
    • Mufson, R.A.1    Myers, C.2    Turpin, J.A.3    Meltzer, M.S.4
  • 23
    • 0026755744 scopus 로고
    • Nuclear expression of the 50- and 65-kD Rel-related subunits of nuclear factor-κB is differentially regulated in human monocytic cells
    • Kaufman, P. A., Weinberg, J. B., Greene, W. C. (1992) Nuclear expression of the 50- and 65-kD Rel-related subunits of nuclear factor-κB is differentially regulated in human monocytic cells. J. Clin. Invest. 90, 121-129.
    • (1992) J. Clin. Invest. , vol.90 , pp. 121-129
    • Kaufman, P.A.1    Weinberg, J.B.2    Greene, W.C.3
  • 24
    • 0027521838 scopus 로고
    • Differential induction of nuclear NF-κB by protein phosphatase inhibitors in primary and transformed human cells
    • Menon, S. D., Qin, S., Guy, G. R., Tan, Y. H. (1993) Differential induction of nuclear NF-κB by protein phosphatase inhibitors in primary and transformed human cells. J. Biol. Chem. 268, 26895-26912.
    • (1993) J. Biol. Chem. , vol.268 , pp. 26895-26912
    • Menon, S.D.1    Qin, S.2    Guy, G.R.3    Tan, Y.H.4
  • 26
    • 0029086519 scopus 로고
    • Unraveling the neuroimmune mechanisms for the HIV-1-associated cognitive/motor complex
    • Nottet, H. S. L. M., Gendelman, H. E. (1995) Unraveling the neuroimmune mechanisms for the HIV-1-associated cognitive/motor complex. Immunol. Today 16, 441-448.
    • (1995) Immunol. Today , vol.16 , pp. 441-448
    • Nottet, H.S.L.M.1    Gendelman, H.E.2
  • 27
    • 0024247501 scopus 로고
    • Tumor necrosis factor and HIV p24 antigen levels in serum of HIV-infected populations
    • Reddy, M. M., Sorrell, S. J., Lange, M., Grieco, M. H. (1988) Tumor necrosis factor and HIV p24 antigen levels in serum of HIV-infected populations. J. Acquir. Immune Defic. Syndr. 1, 436-440.
    • (1988) J. Acquir. Immune Defic. Syndr. , vol.1 , pp. 436-440
    • Reddy, M.M.1    Sorrell, S.J.2    Lange, M.3    Grieco, M.H.4
  • 28
    • 0023696096 scopus 로고
    • Elevated levels of circulating cachectin/tumor necrosis factor in patients with acquired immunodeficiency syndrome
    • Lahdevirta, J., Maury, C. P. J., Teppo, A. M., Repo, H. (1988) Elevated levels of circulating cachectin/tumor necrosis factor in patients with acquired immunodeficiency syndrome. Am. J. Med. 85, 289-291.
    • (1988) Am. J. Med. , vol.85 , pp. 289-291
    • Lahdevirta, J.1    Maury, C.P.J.2    Teppo, A.M.3    Repo, H.4
  • 29
    • 0025969055 scopus 로고
    • Elevated alpha-tumor necrosis factor levels in spinal fluid from HIV-1-infected patients with central nervous system involvement
    • Grimaldi, L. M. E., Martino, G. V, Franciotta, D. M., Brustia, R., Castagna, R., Pristera, R., Lazzarin, A. (1991) Elevated alpha-tumor necrosis factor levels in spinal fluid from HIV-1-infected patients with central nervous system involvement. Ann. Neurol. 29, 21-25.
    • (1991) Ann. Neurol. , vol.29 , pp. 21-25
    • Grimaldi, L.M.E.1    Martino, G.V.2    Franciotta, D.M.3    Brustia, R.4    Castagna, R.5    Pristera, R.6    Lazzarin, A.7
  • 30
    • 0024791849 scopus 로고
    • HIV infection is associated with the spontaneous production of inlerleukin-1 (IL-1) in vivo and with abnormal release of IL-α in vitro
    • Weiss, L., Haeffner-Cavaillon, N., Laude, M., Gilquin, J., Kazatchkine, M. D. (1989) HIV infection is associated with the spontaneous production of inlerleukin-1 (IL-1) in vivo and with abnormal release of IL-α in vitro. AIDS 3, 695-699.
    • (1989) AIDS , vol.3 , pp. 695-699
    • Weiss, L.1    Haeffner-Cavaillon, N.2    Laude, M.3    Gilquin, J.4    Kazatchkine, M.D.5
  • 31
    • 0028930457 scopus 로고
    • A regulatory role for astrocytes in HIV-1 encephalitis: An overexpression of eicosanoids, platelet-activating factor, and tumor necrosis factor-α by activated HIV-1-infected monocytes is attenuated by primary human astrocytes
    • Nottet, H. S. L. M., Jett, M., Flanagan, C. R., Zhai, Q-H., Persidsky, Y., Rizzino, A., Bernton, E. W., Genis, P., Baldwin, T., Schwartz, J., LaBenz, C., Gendelman, H. E. (1995) A regulatory role for astrocytes in HIV-1 encephalitis: an overexpression of eicosanoids, platelet-activating factor, and tumor necrosis factor-α by activated HIV-1-infected monocytes is attenuated by primary human astrocytes. J. Immunol. 154, 3567-3581.
    • (1995) J. Immunol. , vol.154 , pp. 3567-3581
    • Nottet, H.S.L.M.1    Jett, M.2    Flanagan, C.R.3    Zhai, Q.-H.4    Persidsky, Y.5    Rizzino, A.6    Bernton, E.W.7    Genis, P.8    Baldwin, T.9    Schwartz, J.10    LaBenz, C.11    Gendelman, H.E.12


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.