Pharmacology of pediatric resuscitation

Pediatric Clinics of North America

Volumn 44, Issue 1, 1997, Pages 207-233

  Ushay, H M ^a   Notterman, D A ^a  

^a WEILL CORNELL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; ADRENALIN; ATROPINE; BICARBONATE; BRETYLIUM; CALCIUM CHLORIDE; DOBUTAMINE; DOPAMINE; GLUCOSE; LIDOCAINE;

CONTINUOUS INFUSION; DRUG INDUCED DISEASE; HEART ARREST; HEART ARRHYTHMIA; HUMAN; HYPOCALCEMIA; INTRAVENOUS DRUG ADMINISTRATION; ORAL DRUG ADMINISTRATION; PATHOGENESIS; RESUSCITATION; REVIEW;

EID: 0031041469     PISSN: 00313955     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0031-3955(05)70470-3     Document Type: Article

References (131)

1. H.J. Adrogue M.N. Rashad A.B. Gorin Assessing acid-base status in circulatory failure: Differences between arterial and central venous blood N Engl J Med 320 1989 1312 1316
2. C. Alexander Pedal gangrene associated with use of dopamine N Engl J Med 293 1975 591
3. Allen E, et al: Alterations in dopamine clearance and catechol-o-methyltransferase activity by dopamine infusions in children. Crit Care Med, in press
4. American Academy of Pediatrics, Committee on Drugs. Drugs for Pediatric Emergencies. In preparation
5. T.P. Aufderheide D.R. Martin D.W. Olson Prehospital bicarbonate use in cardiac arrest: A 3-year experience Am J Emerg Med 10 1992 4 7
6. C.W. Barton J.E. Manning Cardiopulmonary resuscitation Emerg Med Clin North Am 13 1995 811 829
7. J.R. Benoti Effects of amrinone on myocardial energy metabolism and hemodynamics in patients with severe congestive heart failure due to coronary artery disease Circulation 62 1980 28
8. J. Beregovich C. Bianchi S. Rubler Dose-related hemodynamic and renal effects of dopamine in congestive heart failure Am Heart J 87 1974 550
9. R.A. Berg Dobutamine pharmacokinetics and pharmacodynamics in normal children and adolescents J Pharmacol Exp Ther 265 1993 1232
10. R.A. Berg C.W. Otto K.B. Kern High-dose epinephrine results in greater early mortality after resuscitation from prolonged cardiac arrest in pigs: A prospective, randomized study Crit Care Med 22 1994 282 290
11. R.A. Berg C.W. Otto K.B. Kern A randomized, blinded trial of high-dose epinephrine versus standard-dose epinephrine in a swine model of pediatric asphyxial cardiac arrest Crit Care Med 24 1996 1695 1700
12. J.D. Best J.B. Halter Release and clearance rates of epinephrine in man: Importance of arterial measurements J Clin Endocrinol Metab 55 1982 263 268
13. S. Blecic D. DeBacker M. Deleuze Correction of metabolic acidosis in experimental CPR: A comparative study of sodium bicarbonate, carbicarb, and dextrose Ann Emerg Med 20 1991 235 238
14. R.C. Bone Sepsis and its complications: The clinical problem Crit Care Med 22 1994 8 11
15. R.C. Bone R.A. Balk F.B. Cerra Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis Crit Care Med 20 1992 864 874
16. J. Brillman A. Sanders C. Otto Comparison of epinephrine and phenylephrine for resuscitation and neurologic outcome of cardiac arrest in dogs Ann Emerg Med 16 1987 11 17
17. C.W. Broner G.L. Stidham D.F. Westen-Kirchner A prospective, randomized double-blind comparison of calcium chloride and calcium gluconate therapies for hypocalcemia in critically ill children J Pediatr 117 1990 986 989
18. C. Brown H. Werman Adrenergic agonists during cardiopulmonary resuscitation Resuscitation 19 1990 1 16
19. C.G. Brown E.A. Davis H.A. Werman Methoxamine vs. epinephrine on regional cerebral blood flow during cardiopulmonary resuscitation Crit Care Med 15 1987 682 686
20. C.G. Brown D.R. Martin P.E. Pepe A comparison of standard-dose and high-dose epinephrine in cardiac arrest outside the hospital N Engl J Med 327 1992 1051 1055
21. C. Brown L. Robinson J. Jenkins The effect of norepinephrine vs. epinephrine on regional cerebral flow during cardiopulmonary resuscitation Am J Emerg Med 7 1989 278 282
22. 2-receptor stimulation by circulating epinephrine N Engl J Med 309 1983 1414
23. M. Callaham C.D. Madsen C.W. Barton A randomized clinical trial of high-dose epinephrine and norepinephrine vs standard-dose epinephrine in prehospital cardiac arrest JAMA 286 1992 2667 2672
24. A.J. Camm C.J. Garrat Adenosine and supraventricular tachycardia N Engl J Med 325 1991 1621 1629
25. N. Cardenas-Rivero B. Chernow M.A. Stocko Hypocalcemia in critically ill children J Pediatr 114 1989 946 951
26. B. Chernow T. Rainey R. Lake Endogenous and exogenous catecholamines in critical care medicine Crit Care Med 10 1982 409
27. W.E. Clutter D.M. Bier S.D. Shah Epinephrine plasma metabolic clearance rates and physiologic thresholds for metabolic and hemodynamic actions in man J Clin Invest 66 1980 94 101
28. R.D. Colucci J.C. Somberg Treatment of cardiac arrhythmias B. Chernow The Pharmacologic Approach to the Critically Ill Patient ed 3. 1994 Williams & Wilkins Baltimore 445 469
29. D.J. DeBehnke G.L. Swart D. Spreng Standard and higher doses of atropine in a canine model of pulseless electrical activity Acad Emerg Med 2 1995 1034 1041
30. R.A. Dieckman R. Vardis High-dose epinephrine in pediatric out-of-hospital cardiopulmonary arrest Pediatrics 95 1995 901 913
31. D.J. Driscoll Inotropic response of the neonatal canine myocardium to dopamine Pediatr Res 12 1978 42
32. D.J. Driscoll P.C. Gillette D.G. McNamara The use of dopamine in children J Pediatr 92 1978 309
33. T. Dybvik T. Strand P.A. Steen Buffer therapy during out-of-hospital cardiopulmonary resuscitation Resuscitation 29 1995 89 95
34. S.M. Eleff H. Sugimoto H. Shaffner Acidemia and brain pH during prolonged cardiopulmonary resuscitation in dogs Stroke 26 1995 1028 1034
35. Emergency Cardiac Care Committee and Subcommittees, American Heart Association Guidelines for cardiopulmonary resuscitation and emergency cardiac care JAMA 268 1992 2171 2295
36. C.S. Federiuk A.B. Sanders K.B. Kern The effect of bicarbonate on resuscitation from cardiac arrest Ann Emerg Med 20 1991 1173 1177
37. D.H. Fiser Intraosseous infusion N Engl J Med 322 1990 1579
38. D.G. Fisher P.H. Schwartz A.L. Davis Pharmacokinetics of exogenous epinephrine in critically ill children Crit Care Med 21 1993 111 117
39. M. Fowler Dobutamine and dopamine after cardiac surgery: Greater augmentation of myocardial blood flow with dobutamine Circulation 70 Suppl I 1981 103
40. R.J. Gazmuri M. von Planta M.H. Weil Cardiac effects of carbon dioxide-consuming and carbon dioxide-generating buffers during cardiopulmonary resuscitation J Am Coll Cardiol 15 1990 482 490
41. E. Girardin Effect of low dose dopamine on hemodynamic and renal function in children Pediatr Res 26 1989 200
42. M.G. Goetting Progress in pediatric cardiopulmonary resuscitation Emerg Med Clin North Am 13 1995 291 319
43. M.G. Goetting E. Contreras Systemic atropine administration during cardiac arrest does not cause fixed and dilated pupils Ann Emerg Med 20 1991 55 57
44. M.G. Goetting N.A. Paradis High-dose epinephrine improves outcome from pediatric cardiac arrest Ann Emerg Med 20 1991 22 26
45. M.G. Goetting N.A. Paradis High dose epinephrine in refractory pediatric cardiac arrest Crit Care Med 17 1989 1258 1262
46. F.L. Golbranson Multiple extremity amputations in hypotensive patients treated with dopamine JAMA 243 1980 1145
47. L.I. Goldberg Dopamine: Clinical use of an endogenous catecholamine N Engl J Med 291 1974 707
48. D.S. Goldstein Plasma catecholamine and hemodynamic responses during isoproterenol infusions in humans Clin Pharmacol Ther 40 1986 2
49. E. Gonzalez J. Ornato A. Garnett Dose-dependent vasopressor responses to epinephrine during CPR in human beings Ann Emerg Med 18 1989 920 926
50. S.I. Greene J.W. Smith Dopamine gangrene N Engl J Med 294 1976 114
51. A.D. Guerci N. Chandra E. Johnson Failure of sodium bicarbonate to improve resuscitation from ventricular fibrillation in dogs Circulation 74 suppl IV 1986 75 79
52. U. Gundert-Remy Correlation between the pharmacokinetics and pharmacodynamics of dopamine in healthy subjects Eur J Clin Pharmacol 26 1984 163
53. D.M. Habib Dobutamine pharmacokinetics and pharmacodynamics in pediatric intensive care patients Crit Care Med 20 1992 601 608
54. J. Heller Brown P. Taylor Muscarinic receptor agonists and antagonists J.G. Hardman L.E. Limbird P.B. Molinoff The Pharmacological Basis of Therapeutics ed 9. 1996 McGraw-Hill New York 151
55. B. Hoffman R. Lefkowitz Catecholamines and sympathetic drugs J.G. Hardman L.E. Limbird Goodman & Gilman's The Pharmacologic Basis of Therapeutics ed 9 1996 McGraw-Hill New York
56. M.S. Jasani V.M. Nadkarni M.S. Finkelstein Effects of different techniques of endotracheal epinephrine administration in pediatric porcine hypoxic-hypercarbic cardiopulmonary arrest Crit Care Med 22 1994 1174 1180
57. E. Kentala T. Kaila E. Iisalo Intramuscular atropine in healthy volunteers: A pharmacokinetic and pharmacodynamic study Int J Clin Pharmacol Ther Toxicol 28 1990 399 404
58. F. Kette M.H. Weil M. Von Planta Buffer agents do not reverse intramyocardial acidosis during cardiac resuscitation Circulation 81 1990 1660 1666
59. J.W. Kosnik R.E. Jackson S. Keats Dose-related response of centrally administered epinephrine on the change in aortic diastolic pressure during closed chest massage in dogs Ann Emerg Med 14 1985 204 208
60. J.D. Kugler D.A. Danford Management of infants, children, and adolescents with paroxysmal supraventricular tachycardia J Pediatr 129 1996 324 328
61. M. Kuisma P. Suominen R. Korpela Pediatric out-of-hospital cardiac arrests: Epidemiology and outcome Resuscitation 30 1995 141 150
62. S.C. Kurachek M.A. Rockoff Inadvertent intravenous administration of racemic epinephrine JAMA 253 1985 1441
63. C.V. Leier Comparative systemic and regional hemodynamic effects of dopamine and dobutamine in patients with cardiomyopathic heart failure Circulation 58 1978 466
64. C.V. Leier D.V. Unverferth Dobutamine Ann Intern Med 99 1983 4
65. C.V. Leier D.V. Unverferth R.E. Kates The relationship between plasma dobutamine concentrations and cardiovascular responses in cardiac failure Am J Med 66 1979 238
66. F. Lemaire Effect of catecholamines on pulmonary right-to-left shunt Int Anesthesiol Clin 21 1983 43
67. D.H. Levine Renal failure and other serious sequelae of epinephrine toxicity in neonates South Med J 78 1985 874
68. R.R. Liberthson Sudden death from cardiac causes in children and young adults N Engl J Med 334 1996 1039 1044
69. K.H. Lindner F.W. Ahnefeld Comparison of epinephrine and norepinephrine in the treatment of asphyxial or fibrillatory cardiac arrest in a procine model Crit Care Med 17 1989 437 441
70. K.H. Lindner F.W. Ahnefeld A. Grunert Epinephrine vs. norepinephrine in prehospital ventricular fibrillation Am J Cardiol 67 1991 427 428
71. S.E. Lucking M.M. Pollack A.I. Fields Shock following generalized hypoxic ischemic injury in previously healthy infants and children J Pediatr 108 1986 359
72. K.L. MacCannell Hemodynamic responses to dopamine and dobutamine infusions as a function of duration of infusion Pharmacology 26 1983 29
73. R. Magorien D. Unverferth G. Brown Dobutamine and hydralazine: Comparative influences of positive inotropy and vasodilatation on coronary blood flow and energetics in nonischemic congestive heart failure J Am Coll Cardiol 1 1983 499
74. T.C. Majerus Dobutamine: Ten years later Pharmacotherapy 9 1989 245
75. J.E. Manning C.A. Murphy D.N. Batson Aortic arch versus central venous epinephrine during CPR Ann Emerg Med 22 1993 703 707
76. A.M. Martinez J.F. Padbury S. Thio Dobutamine pharmacokinetics and cardiovascular responses in critically ill neonates Pediatrics 89 1992 47 51
77. J.K. Michael A.D. Guerci R.C. Koehler Mechanisms by which epinephrine augments cerebral and myocardial perfusion during cardiopulmonary resuscitation in dogs Circulation 69 1984 822 835
78. J.L. Moran Epinephrine as an inotropic agent in septic shock: A dose-profile analysis Crit Care Med 21 1993 70
79. H. Mueller S. Ayres J. Gregory Hemodynamics, coronary blood flow, and myocardial metabolism in coronary shock: Response to l-epinephrine and isoproterenol J Clin Invest 49 1970 1885
80. S. Nattel G. Gagne M. Pineau The pharmacokinetics of lignocaine and β-adrenoreceptor antagonists in patients with acute myocardial infarction Clin Pharmacokinet 13 1987 293 316
81. D.A. Notterman Cardiovascular support-pharmacologic P.R. Holbrook Pediatric Critical Care 1993 WB Saunders Philadelphia 288 315
82. D.A. Notterman Inotropic agents Crit Care Clin 7 1991 583
83. D.A. Notterman Pharmacology of the Cardiovascular System B.P. Fuhrman J.J. Zimmerman Pediatric Critical Care 1992 Mosby-Year Book St. Louis 323 344
84. D.A. Notterman Dopamine clearance in critically ill infants and children: Effect of age and organ system dysfunction Clin Pharmacol Ther 48 1990 138
85. D.W. Olson R. Thakur H.A. Stueven Randomized study of epinephrine vs. methoxamine in prehospital ventricular fibrillation Ann Emerg Med 18 1989 250 253
86. J.P. Orlowski D.T. Porembka J.M. Gallagher Comparison study of intraosseous, central intravenous, and peripheral intravenous infusions of emergency drugs Am J Dis Child 144 1990 112 117
87. C. Otto R. Yakaitis C. Blitt Mechanism of action of epinephrine in resuscitation from asphyxial arrest Crit Care Med 9 1984 321 324
88. J.F. Padbury Dopamine pharmacokinetics in critically ill newborn infants J Pediatr 110 1987 2
89. N.A. Paradis G.B. Martin E.P. Rivers Coronary perfusion pressure and the return of spontaneous circulation in human cardiopulmonary resuscitation JAMA 263 1990 1106 1113
90. W.D. Patrick J. Freedman T. McEwen A randomized, double blind comparison of methoxamine and epinephrine in human cardiopulmonary arrest Am J Respir Crit Care Med 152 1995 519 523
91. C.A. Perez Effect of high dose dopamine on urine output in newborn infants Crit Care Med 14 1986 1045
92. R.M. Perkin D.L. Levin R. Webb Dobutamine: A hemodynamic evaluation in children with shock J Pediatr 100 1982 977
93. S.L. Platt D.A. Notterman P. Winchester Fungal osteomyelitis and sepsis from intraosseous infusion Pediatr Emerg Care 9 1993 149 150
94. W.G. Rapeport Clinical pharmacokinetics of bretylium Clin Pharmacokinet 10 1985 248 256
95. R. Ronco W. King D.K. Donley Outcome and cost at a children's hospital following resuscitation for out-of-hospital cardiopulmonary arrest Arch Pediatr Adolesc Med 149 1995 210 214
96. K.H. Rhee L.O. Toro G.G. McDonald Carbicarb, sodium bicarbonate, and sodium chloride in hypoxic lactic acidosis-effect on arterial blood gases, lactate concentrations, hemodynamic variables, and myocardial intracellular pH Chest 104 1993 913 918
97. S.G. Rockson Cellular mechanisms of impaired adrenergic responsiveness in neonatal dogs J Clin Invest 67 1981 319
98. D.M. Roden Antiarrhythmic drugs J.G. Hardman L.E. Limbird P.B. Molinoff Goodman and Gilman's The Pharmacological Basis of Therapeutics ed 9 1996 McGraw Hill New York 858 866
99. T. Sakamoto T. Yamada Hemodynamic effects of dobutamine in patients following open heart surgery Circulation 55 1977 525
100. M.B. Schindler D. Bohn P.N. Cox Outcome of out-of-hospital cardiac or respiratory arrest in children N Engl J Med 335 1996 1473 1479
101. D. Schrantz Hemodynamic effects of dobutamine in children with cardiovascular failure Eur J Pediatr 139 1982 4
102. K.F. Schulze Physiologic oscillations produced by an infusion pump J Pediatr 103 1986 5
103. I. Seri Cardiovascular response to dopamine in hypotensive preterm neonates with severe hyaline membrane disease Eur J Pediatr 142 1984 3
104. I. Seri T. Tulassay J. Kiszel Effect of low dose dopamine infusion on prolactin and thyrotropin secretion in preterm infants with hyaline membrane disease Biol Neonate 47 1985 317
105. N. Shapiro H.V. Schaff R.D. White Hemodynamic effects of calcium chloride injection following cardiopulmonary bypass: Response to bolus injection and continuous infusion Ann Thorac Surg 37 1984 133 140
106. S.L. Solomon Medication errors with inhalant epinephrine mimicking an epidemic of neonatal sepsis N Engl J Med 310 1984 166
107. P.A. Steen Efficacy of dopamine, dobutamine, and epinephrine during emergence from cardiopulmonary bypass in man Circulation 57 1978 378
108. C. Steinberg D.A. Notterman Pharmacokinetics of cardiovascular drugs in children Clin Pharmacokinet 27 1994 345 367
109. I.G. Stiell P.C. Hebert B.N. Weitzman High-dose epinephrine in adult cardiac arrest N Engl J Med 327 1992 1045 1050
110. P.M. Stilz D. Scheidegger L.J. Drop Ventricular pump performance during hypocalcemia: Clinical and experimental studies J Thorac Cardiovasc Surg 78 1979 185 194
111. J.D. Stoner II J.L. Bolen D.C. Harrison Comparison of dobutamine and dopamine in treatment of severe heart failure Br Heart J 39 1977 536
112. W. Tang M.H. Weil R.J. Gazmuri Reversible impairment of myocardial contractility caused by hypercarbic acidosis in isolated perfused rat heart Crit Care Med 19 1991 218 224
113. W. Tang M.H. Weil S. Sun Epinephrine increases the severity of postresuscitation myocardial dysfunction Circulation 92 1995 3089 3093
114. P.D. Thompson K.L. Melmon J.A. Richardson Lidocaine pharmacokinetics in advanced heart failure, liver disease, and renal failure in humans Ann Intern Med 78 1973 499 508
115. T. Tulassay W. Rascher K. Scharer Effect of low dose dopamine on kidney function and vasoactive hormones in pediatric patients with advanced renal failure Clin Nephrol 28 1987 22
116. L.M. Turner M. Parsons R.C. Luetkemeyer A comparison of epinephrine and methoxamine for resuscitation from electromechanical dissociation in human beings Ann Emerg Med 17 1988 443 449
117. G. van den Berghe F. de Zegher P. Lauwers Dopamine suppresses pituitary function in infants and children Crit Care Med 22 1994 1747
118. M. von Planta G. Bar-Joseph L. Wiklund Pathophysiologic and therapeutic implications of acid-base changes during CPR Ann Emerg Med 22 1993 404 410
119. 2 production during cardiac arrest and resuscitation Circulation 80 1989 684 692
120. I. von Planta M.H. Weil M. von Planta Hypercarbic acidosis reduces cardiac resuscitability Crit Care Med 19 1991 1177 1182
121. R.B. Vukmir N.G. Bircher A. Radovsky Sodium bicarbonate may improve outcome in dogs with brief or prolonged cardiac arrest Crit Care Med 23 1995 515 522
122. D. Ward J. Bellville Reduction of hypoxic ventilatory drive by dopamine Anesth Anal 61 1982 333
123. M.H. Weil E.C. Rackow R. Trevino Difference in acid-base state between venous and arterial blood during cardiopulmonary resuscitation N Engl J Med 315 1986 153 156
124. R.F. Wilson W.J. Sibbald J.L. Jaanimagi Hemodynamic effects of dopamine in critically ill septic patients J Surg Res 20 1976 163
125. A.L. Zaritsky Bicarbonate in cardiac arrest: The good, the bad, and the puzzling Crit Care Med 23 1995 429 431
126. A.L. Zaritsky Endotracheal epinephrine in cardiac arrest Crit Care Med 22 1994 1071 1072
127. A.L. Zaritsky Pediatric resuscitation pharmacology Ann Emerg Med 22 1993 445 455
128. A.L. Zaritsky Resuscitation pharmacology B. Chernow The Pharmacologic Approach to the Critically Ill Patient ed 3. 1994 Williams & Wilkens Baltimore 233
129. A.L. Zaritsky B. Chernow Use of catecholamines in pediatrics J Pediatr 105 1984 341
130. A.L. Zaritsky A. Lotze R. Stull Steady state dopamine clearance in critically ill infants and children Crit Care Med 16 1988 3
131. A.L. Zaritsky V. Nadkarni P. Getson CPR in children Ann Emerg Med 16 1987 1107 1111