Inhibitory mechanism of serpins. Mobility of the C-terminal region of the reactive-site loop

Journal of Biological Chemistry

Volumn 272, Issue 7, 1997, Pages 3905-3909

  Hopkins, Paul C R ^a,b   Chang, Wun Shiang W ^a   Wardell, Mark R ^a,c   Stone, Stuart R ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b GLADSTONE INSTITUTE OF CARDIOVASCULAR DISEASE   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ANTITRYPSIN; RECOMBINANT PROTEIN; SERINE PROTEINASE INHIBITOR;

ARTICLE; CARBOXY TERMINAL SEQUENCE; DISULFIDE BOND; ENZYME ACTIVE SITE; ENZYME INHIBITION; ENZYME MECHANISM; INHIBITION KINETICS; MOLECULAR DYNAMICS; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE;

ALPHA 1-ANTITRYPSIN; BINDING SITES; DISULFIDES; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; LEUKOCYTE ELASTASE; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; SUBSTRATE SPECIFICITY;

EID: 0031041451     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.7.3905     Document Type: Article

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